GBP4 guanylate binding protein 4 [Bos taurus (cattle)] - Gene

Summary

Gene symbol: GBP4
Gene description: guanylate binding protein 4
See related: BGD:BT22829
Gene type: protein coding
RefSeq status: PROVISIONAL
Organism: Bos taurus
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Artiodactyla; Ruminantia; Pecora; Bovidae; Bovinae; Bos
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Genomic context

Location:: chromosome: 3

Exon count:: 14

Annotation release	Status	Assembly	Chr	Location
RS_2023_09	current	ARS-UCD2.0 (GCF_002263795.3)	3	NC_037330.1 (54451307..54507575)

Chromosome 3 - NC_037330.1 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Go to reference sequence details

Genomic Sequence:: NC_037330.1 Chromosome 3 Reference ARS-UCD2.0 Primary Assembly

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

GBP4 is a positional candidate determining adult cattle stature.
Title: Integrating CNVs into meta-QTL identified GBP4 as positional candidate for adult cattle stature.

Submit: New GeneRIF Correction

General gene information

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Gene Ontology Provided by RefSeq

Function	Evidence Code	Pubs
enables GTP binding	IEA Inferred from Electronic Annotation more info	PubMed
enables GTPase activity	IEA Inferred from Electronic Annotation more info	PubMed

Process	Evidence Code	Pubs
involved_in defense response to Gram-positive bacterium	IEA Inferred from Electronic Annotation more info	PubMed
involved_in defense response to protozoan	IEA Inferred from Electronic Annotation more info	PubMed

General protein information

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Preferred Names: guanylate binding protein 4

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

NM_001102261.2 → NP_001095731.1 guanylate binding protein 4

See identical proteins and their annotated locations for NP_001095731.1

Status: PROVISIONAL

Source sequence(s)

BC149507

UniProtKB/TrEMBL

A6QPV3

Conserved Domains (2) summary

pfam02263
Location:11 → 273

GBP; Guanylate-binding protein, N-terminal domain

pfam02841
Location:275 → 571

GBP_C; Guanylate-binding protein, C-terminal domain

RefSeqs of Annotated Genomes: GCF_002263795.3-RS_2023_09

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference ARS-UCD2.0 Primary Assembly

Genomic

NC_037330.1 Reference ARS-UCD2.0 Primary Assembly

Range

54451307..54507575

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GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

XM_005204307.5 → XP_005204364.1 guanylate binding protein 4 isoform X2

See identical proteins and their annotated locations for XP_005204364.1

UniProtKB/TrEMBL

A6QPV3

Conserved Domains (2) summary

pfam02263
Location:11 → 273

GBP; Guanylate-binding protein, N-terminal domain

pfam02841
Location:275 → 571

GBP_C; Guanylate-binding protein, C-terminal domain
XM_059884841.1 → XP_059740824.1 guanylate binding protein 4 isoform X3
XM_059884840.1 → XP_059740823.1 guanylate binding protein 4 isoform X1