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STIM1 stromal interaction molecule 1 [ Canis lupus familiaris (dog) ]

Gene ID: 608643, updated on 5-Mar-2024

Summary

Official Symbol
STIM1provided by VGNC
Official Full Name
stromal interaction molecule 1provided by VGNC
Primary source
VGNC:VGNC:46901
See related
Ensembl:ENSCAFG00845011568
Gene type
protein coding
RefSeq status
MODEL
Organism
Canis lupus familiaris (sub-species: familiaris)
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Carnivora; Caniformia; Canidae; Canis
Orthologs
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Genomic context

Location:
chromosome: 21
Exon count:
15
Annotation release Status Assembly Chr Location
106 current ROS_Cfam_1.0 (GCF_014441545.1) 21 NC_051825.1 (26605233..26804185)
106 current Dog10K_Boxer_Tasha (GCF_000002285.5) 21 NC_006603.4 (26165634..26364115)
106 current UU_Cfam_GSD_1.0 (GCF_011100685.1) 21 NC_049242.1 (26514667..26713342)
106 current UMICH_Zoey_3.1 (GCF_005444595.1) 21 NC_049281.1 (26396567..26594567)
106 current UNSW_CanFamBas_1.0 (GCF_013276365.1) 21 NC_049762.1 (26612342..26810837)

Chromosome 21 - NC_051825.1Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC119864880 Neighboring gene ras homolog family member G Neighboring gene ribonucleotide reductase catalytic subunit M1 Neighboring gene olfactory receptor family 55 subfamily B member 1

Genomic regions, transcripts, and products

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables calcium channel regulator activity IEA
Inferred from Electronic Annotation
more info
PubMed 
enables calcium ion binding IEA
Inferred from Electronic Annotation
more info
PubMed 
enables protein binding IEA
Inferred from Electronic Annotation
more info
PubMed 
Process Evidence Code Pubs
involved_in activation of store-operated calcium channel activity IEA
Inferred from Electronic Annotation
more info
PubMed 
involved_in intracellular calcium ion homeostasis IEA
Inferred from Electronic Annotation
more info
PubMed 
involved_in store-operated calcium entry IEA
Inferred from Electronic Annotation
more info
PubMed 
Component Evidence Code Pubs
located_in endoplasmic reticulum IEA
Inferred from Electronic Annotation
more info
PubMed 
located_in plasma membrane IEA
Inferred from Electronic Annotation
more info
PubMed 

General protein information

Preferred Names
stromal interaction molecule 1

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Canis lupus familiaris Annotation Release 106 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference ROS_Cfam_1.0

Genomic

  1. NC_051825.1 Reference ROS_Cfam_1.0

    Range
    26605233..26804185
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038430296.1XP_038286224.1  stromal interaction molecule 1 isoform X4

    Conserved Domains (3) summary
    cd09573
    Location:128201
    SAM_STIM1; SAM domain of STIM1 subfamily proteins
    COG1196
    Location:237434
    Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]
    pfam16533
    Location:344441
    SOAR; STIM1 Orai1-activating region
  2. XM_038430298.1XP_038286226.1  stromal interaction molecule 1 isoform X5

    UniProtKB/TrEMBL
    A0A8C0TIM1, A0A8I3NFR6
    Related
    ENSCAFP00845016088.1, ENSCAFT00845020519.1
    Conserved Domains (3) summary
    cd09573
    Location:128201
    SAM_STIM1; SAM domain of STIM1 subfamily proteins
    COG1196
    Location:237434
    Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]
    pfam16533
    Location:344441
    SOAR; STIM1 Orai1-activating region
  3. XM_038430293.1XP_038286221.1  stromal interaction molecule 1 isoform X1

    UniProtKB/TrEMBL
    A0A8C0K6T8, A0A8C0RP45, A0A8C0Z4D1, A0A8I3RWM0
    Related
    ENSCAFP00845016145.1, ENSCAFT00845020582.1
    Conserved Domains (3) summary
    cd09573
    Location:128201
    SAM_STIM1; SAM domain of STIM1 subfamily proteins
    COG1196
    Location:237434
    Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]
    pfam16533
    Location:344441
    SOAR; STIM1 Orai1-activating region
  4. XM_038430294.1XP_038286222.1  stromal interaction molecule 1 isoform X2

    UniProtKB/TrEMBL
    A0A8C0K7H7, A0A8C0NYT0, A0A8I3NK53, A0A8P0N8G3
    Related
    ENSCAFP00845016122.1, ENSCAFT00845020556.1
    Conserved Domains (3) summary
    cd09573
    Location:128201
    SAM_STIM1; SAM domain of STIM1 subfamily proteins
    COG1196
    Location:237434
    Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]
    pfam16533
    Location:344441
    SOAR; STIM1 Orai1-activating region
  5. XM_038430295.1XP_038286223.1  stromal interaction molecule 1 isoform X3

    UniProtKB/TrEMBL
    A0A8C0Z4D1
    Conserved Domains (3) summary
    cd09573
    Location:90163
    SAM_STIM1; SAM domain of STIM1 subfamily proteins
    COG1196
    Location:199396
    Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]
    pfam16533
    Location:306403
    SOAR; STIM1 Orai1-activating region

Alternate UMICH_Zoey_3.1

Genomic

  1. NC_049281.1 Alternate UMICH_Zoey_3.1

    Range
    26396567..26594567
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038505638.1XP_038361566.1  stromal interaction molecule 1 isoform X4

    Conserved Domains (3) summary
    cd09573
    Location:128201
    SAM_STIM1; SAM domain of STIM1 subfamily proteins
    COG1196
    Location:237434
    Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]
    pfam16533
    Location:344441
    SOAR; STIM1 Orai1-activating region
  2. XM_038505639.1XP_038361567.1  stromal interaction molecule 1 isoform X5

    Conserved Domains (3) summary
    cd09573
    Location:128201
    SAM_STIM1; SAM domain of STIM1 subfamily proteins
    COG1196
    Location:237434
    Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]
    pfam16533
    Location:344441
    SOAR; STIM1 Orai1-activating region
  3. XM_038505635.1XP_038361563.1  stromal interaction molecule 1 isoform X1

    Conserved Domains (3) summary
    cd09573
    Location:128201
    SAM_STIM1; SAM domain of STIM1 subfamily proteins
    COG1196
    Location:237434
    Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]
    pfam16533
    Location:344441
    SOAR; STIM1 Orai1-activating region
  4. XM_038505636.1XP_038361564.1  stromal interaction molecule 1 isoform X2

    Conserved Domains (3) summary
    cd09573
    Location:128201
    SAM_STIM1; SAM domain of STIM1 subfamily proteins
    COG1196
    Location:237434
    Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]
    pfam16533
    Location:344441
    SOAR; STIM1 Orai1-activating region
  5. XM_038505637.1XP_038361565.1  stromal interaction molecule 1 isoform X3

    Conserved Domains (3) summary
    cd09573
    Location:90163
    SAM_STIM1; SAM domain of STIM1 subfamily proteins
    COG1196
    Location:199396
    Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]
    pfam16533
    Location:306403
    SOAR; STIM1 Orai1-activating region

Alternate UNSW_CanFamBas_1.0

Genomic

  1. NC_049762.1 Alternate UNSW_CanFamBas_1.0

    Range
    26612342..26810837
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038633001.1XP_038488929.1  stromal interaction molecule 1 isoform X4

    Conserved Domains (3) summary
    cd09573
    Location:128201
    SAM_STIM1; SAM domain of STIM1 subfamily proteins
    COG1196
    Location:237434
    Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]
    pfam16533
    Location:344441
    SOAR; STIM1 Orai1-activating region
  2. XM_038632998.1XP_038488926.1  stromal interaction molecule 1 isoform X1

    Conserved Domains (3) summary
    cd09573
    Location:128201
    SAM_STIM1; SAM domain of STIM1 subfamily proteins
    COG1196
    Location:237434
    Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]
    pfam16533
    Location:344441
    SOAR; STIM1 Orai1-activating region
  3. XM_038633002.1XP_038488930.1  stromal interaction molecule 1 isoform X5

    Conserved Domains (3) summary
    cd09573
    Location:128201
    SAM_STIM1; SAM domain of STIM1 subfamily proteins
    COG1196
    Location:237434
    Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]
    pfam16533
    Location:344441
    SOAR; STIM1 Orai1-activating region
  4. XM_038632999.1XP_038488927.1  stromal interaction molecule 1 isoform X2

    Conserved Domains (3) summary
    cd09573
    Location:128201
    SAM_STIM1; SAM domain of STIM1 subfamily proteins
    COG1196
    Location:237434
    Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]
    pfam16533
    Location:344441
    SOAR; STIM1 Orai1-activating region
  5. XM_038633000.1XP_038488928.1  stromal interaction molecule 1 isoform X3

    Conserved Domains (3) summary
    cd09573
    Location:90163
    SAM_STIM1; SAM domain of STIM1 subfamily proteins
    COG1196
    Location:199396
    Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]
    pfam16533
    Location:306403
    SOAR; STIM1 Orai1-activating region

Alternate UU_Cfam_GSD_1.0

Genomic

  1. NC_049242.1 Alternate UU_Cfam_GSD_1.0

    Range
    26514667..26713342
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038568832.1XP_038424760.1  stromal interaction molecule 1 isoform X4

    Conserved Domains (3) summary
    cd09573
    Location:128201
    SAM_STIM1; SAM domain of STIM1 subfamily proteins
    COG1196
    Location:237434
    Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]
    pfam16533
    Location:344441
    SOAR; STIM1 Orai1-activating region
  2. XM_038568833.1XP_038424761.1  stromal interaction molecule 1 isoform X5

    UniProtKB/TrEMBL
    A0A8C0TIM1, A0A8I3NFR6
    Conserved Domains (3) summary
    cd09573
    Location:128201
    SAM_STIM1; SAM domain of STIM1 subfamily proteins
    COG1196
    Location:237434
    Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]
    pfam16533
    Location:344441
    SOAR; STIM1 Orai1-activating region
  3. XM_038568828.1XP_038424756.1  stromal interaction molecule 1 isoform X1

    UniProtKB/TrEMBL
    A0A8C0K6T8, A0A8C0RP45, A0A8C0Z4D1, A0A8I3RWM0
    Conserved Domains (3) summary
    cd09573
    Location:128201
    SAM_STIM1; SAM domain of STIM1 subfamily proteins
    COG1196
    Location:237434
    Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]
    pfam16533
    Location:344441
    SOAR; STIM1 Orai1-activating region
  4. XM_038568830.1XP_038424758.1  stromal interaction molecule 1 isoform X2

    UniProtKB/TrEMBL
    A0A8C0K7H7, A0A8C0NYT0, A0A8I3NK53, A0A8P0N8G3
    Conserved Domains (3) summary
    cd09573
    Location:128201
    SAM_STIM1; SAM domain of STIM1 subfamily proteins
    COG1196
    Location:237434
    Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]
    pfam16533
    Location:344441
    SOAR; STIM1 Orai1-activating region
  5. XM_038568831.1XP_038424759.1  stromal interaction molecule 1 isoform X3

    UniProtKB/TrEMBL
    A0A8C0Z4D1
    Conserved Domains (3) summary
    cd09573
    Location:90163
    SAM_STIM1; SAM domain of STIM1 subfamily proteins
    COG1196
    Location:199396
    Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]
    pfam16533
    Location:306403
    SOAR; STIM1 Orai1-activating region

Alternate Dog10K_Boxer_Tasha Primary Assembly

Genomic

  1. NC_006603.4 Alternate Dog10K_Boxer_Tasha Primary Assembly

    Range
    26165634..26364115
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038456153.1XP_038312081.1  stromal interaction molecule 1 isoform X4

    Conserved Domains (3) summary
    cd09573
    Location:128201
    SAM_STIM1; SAM domain of STIM1 subfamily proteins
    COG1196
    Location:237434
    Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]
    pfam16533
    Location:344441
    SOAR; STIM1 Orai1-activating region
  2. XM_003433013.5XP_003433061.1  stromal interaction molecule 1 isoform X5

    UniProtKB/TrEMBL
    A0A8C0TIM1, A0A8I3NFR6
    Conserved Domains (3) summary
    cd09573
    Location:128201
    SAM_STIM1; SAM domain of STIM1 subfamily proteins
    COG1196
    Location:237434
    Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]
    pfam16533
    Location:344441
    SOAR; STIM1 Orai1-activating region
  3. XM_005633577.4XP_005633634.1  stromal interaction molecule 1 isoform X1

    UniProtKB/TrEMBL
    A0A8C0K6T8, A0A8C0RP45, A0A8C0Z4D1, A0A8I3RWM0
    Conserved Domains (3) summary
    cd09573
    Location:128201
    SAM_STIM1; SAM domain of STIM1 subfamily proteins
    COG1196
    Location:237434
    Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]
    pfam16533
    Location:344441
    SOAR; STIM1 Orai1-activating region
  4. XM_845570.6XP_850663.1  stromal interaction molecule 1 isoform X2

    UniProtKB/TrEMBL
    A0A8C0K7H7, A0A8C0NYT0, A0A8I3NK53, A0A8P0N8G3
    Conserved Domains (3) summary
    cd09573
    Location:128201
    SAM_STIM1; SAM domain of STIM1 subfamily proteins
    COG1196
    Location:237434
    Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]
    pfam16533
    Location:344441
    SOAR; STIM1 Orai1-activating region
  5. XM_022407752.2XP_022263460.1  stromal interaction molecule 1 isoform X3

    UniProtKB/TrEMBL
    A0A8C0Z4D1
    Conserved Domains (3) summary
    cd09573
    Location:90163
    SAM_STIM1; SAM domain of STIM1 subfamily proteins
    COG1196
    Location:199396
    Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]
    pfam16533
    Location:306403
    SOAR; STIM1 Orai1-activating region