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PRKCI protein kinase C iota [ Macaca mulatta (Rhesus monkey) ]

Gene ID: 574352, updated on 5-Mar-2024

Summary

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Official Symbol
PRKCIprovided by VGNC
Official Full Name
protein kinase C iotaprovided by VGNC
Primary source
VGNC:VGNC:84064
See related
Ensembl:ENSMMUG00000011222
Gene type
protein coding
RefSeq status
MODEL
Organism
Macaca mulatta
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Cercopithecidae; Cercopithecinae; Macaca
Orthologs
human mouse all
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Genomic context

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Location:
chromosome: 2
Exon count:
19
Annotation release Status Assembly Chr Location
103 current Mmul_10 (GCF_003339765.1) 2 NC_041755.1 (75155808..75241444)
102 previous assembly Mmul_8.0.1 (GCF_000772875.2) 2 NC_027894.1 (123484529..123573795, complement)

Chromosome 2 - NC_041755.1Genomic Context describing neighboring genes Neighboring gene polyhomeotic homolog 3 Neighboring gene U6 spliceosomal RNA Neighboring gene U7 small nuclear RNA Neighboring gene SKI like proto-oncogene Neighboring gene claudin 11

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Elevated gene expression levels distinguish human from non-human primate brains. Cáceres M, et al. Proc Natl Acad Sci U S A, 2003 Oct 28. PMID 14557539, Free PMC Article
  2. A new rhesus macaque assembly and annotation for next-generation sequencing analyses. Zimin AV, et al. Biol Direct, 2014 Oct 14. PMID 25319552, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Markers

Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables ATP binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables diacylglycerol-dependent serine/threonine kinase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables protein binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in protein phosphorylation IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
protein kinase C iota type
XP_014987118.1
XP_014987119.1

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Macaca mulatta Annotation Release 103 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference Mmul_10 Primary Assembly

Genomic

  1. NC_041755.1 Reference Mmul_10 Primary Assembly

    Range
    75155808..75241444
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_015131632.2 → XP_014987118.1  protein kinase C iota type isoform X1

    UniProtKB/TrEMBL
    A0A5F7Z9M4, A0A5F7ZX99
    Related
    ENSMMUP00000069262.1, ENSMMUT00000108935.1
    Conserved Domains (4) summary
    cd06404
    Location:120 → 202
    PB1_aPKC; PB1 domain is an essential modular domain of the atypical protein kinase C (aPKC) which in complex with Par6 and Par3 proteins is crucial for establishment of apical-basal polarity of animal cells. PB1 domain is a modular domain mediating specific ...
    smart00220
    Location:348 → 616
    S_TKc; Serine/Threonine protein kinases, catalytic domain
    cd05618
    Location:327 → 690
    STKc_aPKC_iota; Catalytic domain of the Serine/Threonine Kinase, Atypical Protein Kinase C iota
    pfam00130
    Location:235 → 287
    C1_1; Phorbol esters/diacylglycerol binding domain (C1 domain)

  2. XM_015131633.2 → XP_014987119.1  protein kinase C iota type isoform X2

    UniProtKB/TrEMBL
    A0A1D5RJL1, G7MJB3
    Related
    ENSMMUP00000060505.1, ENSMMUT00000075873.2
    Conserved Domains (3) summary
    cd06404
    Location:3 → 79
    PB1_aPKC; PB1 domain is an essential modular domain of the atypical protein kinase C (aPKC) which in complex with Par6 and Par3 proteins is crucial for establishment of apical-basal polarity of animal cells. PB1 domain is a modular domain mediating specific ...
    cd05618
    Location:204 → 567
    STKc_aPKC_iota; Catalytic domain of the Serine/Threonine Kinase, Atypical Protein Kinase C iota
    cd20794
    Location:110 → 164
    C1_aPKC; protein kinase C conserved region 1 (C1 domain) found in the atypical protein kinase C (aPKC) family
Nucleotide Protein
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