Gene description

GTP cyclohydrolase I

Locus Tag

CCC13826_1778

Gene type

protein coding

RefSeq status

Provisional

Organism

Campylobacter concisus 13826

Lineage

Bacteria; Proteobacteria; Epsilonproteobacteria; Campylobacterales; Campylobacteraceae; Campylobacter

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Names

GTP cyclohydrolase I

YP_001465994.1

EC 3.5.4.16

involved in the first step of tetrahydrofolate biosynthesis; catalyzes the formation of formate and 2-amino-4-hydroxy-6-(erythro-1,2,3-trihydroxypropyl)dihydropteridine triphosphate from GTP and water; forms a homopolymer

Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

This section includes genomic Reference Sequences (RefSeqs) from all assemblies on which this gene is annotated, such as RefSeqs for chromosomes and scaffolds (contigs) from both reference and alternate assemblies. Model RNAs and proteins are also reported here.

mRNA and Protein(s)

1. YP_001465994.1 GTP cyclohydrolase I [Campylobacter concisus 13826]

   UniProtKB/Swiss-Prot

   A7ZB36

   Conserved Domains (1) summary

   cd00642
   Location:2 – 184
   Blast Score: 620

   GTP_cyclohydro1; GTP cyclohydrolase I (GTP-CH-I) catalyzes the conversion of GTP into dihydroneopterin triphosphate. The enzyme product is the precursor of tetrahydrofolate in eubacteria, fungi, and plants and of the folate analogs in methanogenic bacteria. In...