cdc25d cell division cycle 25 homolog d [Danio rerio (zebrafish)] - Gene

Summary

Official Symbol: cdc25dprovided by ZNC
Official Full Name: cell division cycle 25 homolog dprovided by ZNC
Primary source: ZFIN:ZDB-GENE-090313-74
See related: Ensembl:ENSDARG00000075599 AllianceGenome:ZFIN:ZDB-GENE-090313-74
Gene type: protein coding
RefSeq status: PROVISIONAL
Organism: Danio rerio
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
Also known as: si:ch211-202h22.3
Summary: Enables phosphoprotein phosphatase activity. Acts upstream of or within regulation of G2/M transition of mitotic cell cycle. Predicted to be active in cytoplasm and nucleus. Is expressed in olfactory placode and somite. [provided by Alliance of Genome Resources, Apr 2022]
Orthologs: all
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Genomic context

Location:: chromosome: 1

Exon count:: 12

Annotation release	Status	Assembly	Chr	Location
106	current	GRCz11 (GCF_000002035.6)	1	NC_007112.7 (54720906..54735500, complement)
105	previous assembly	GRCz10 (GCF_000002035.5)	1	NC_007112.6 (54043255..54057809, complement)

Chromosome 1 - NC_007112.7 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

Expression

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See details

Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
BioProject: PRJEB1986
Analysis date: Fri Dec 8 19:48:10 2017

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

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General gene information

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Gene Ontology Provided by ZFIN

Function	Evidence Code	Pubs
enables hydrolase activity	IEA Inferred from Electronic Annotation more info
enables phosphoprotein phosphatase activity	IDA Inferred from Direct Assay more info	PubMed
enables phosphoprotein phosphatase activity	IEA Inferred from Electronic Annotation more info
enables protein tyrosine phosphatase activity	IBA Inferred from Biological aspect of Ancestor more info
enables protein tyrosine phosphatase activity	IEA Inferred from Electronic Annotation more info

Process	Evidence Code	Pubs
involved_in G2/M transition of mitotic cell cycle	IBA Inferred from Biological aspect of Ancestor more info
acts_upstream_of_or_within cell cycle	IEA Inferred from Electronic Annotation more info
acts_upstream_of_or_within cell division	IEA Inferred from Electronic Annotation more info
involved_in positive regulation of G2/M transition of mitotic cell cycle	IBA Inferred from Biological aspect of Ancestor more info
involved_in positive regulation of G2/MI transition of meiotic cell cycle	IBA Inferred from Biological aspect of Ancestor more info
acts_upstream_of_or_within positive regulation of cell cycle G2/M phase transition	IEA Inferred from Electronic Annotation more info
acts_upstream_of_or_within regulation of G2/M transition of mitotic cell cycle	IMP Inferred from Mutant Phenotype more info	PubMed

Component	Evidence Code	Pubs
is_active_in cytoplasm	IBA Inferred from Biological aspect of Ancestor more info
is_active_in nucleus	IBA Inferred from Biological aspect of Ancestor more info

General protein information

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Preferred Names: cell division cycle 25 homolog d

Names: cdc25d protein (cdc25d)

NP_001128154.1

EC 3.1.3.48

XP_017210413.1

EC 3.1.3.48

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

NM_001134682.1 → NP_001128154.1 cell division cycle 25 homolog d

See identical proteins and their annotated locations for NP_001128154.1

Status: PROVISIONAL

Source sequence(s)

EU921897

UniProtKB/TrEMBL

B5LY74

Related

ENSDARP00000098278.2, ENSDART00000109089.3

Conserved Domains (2) summary

COG5105
Location:72 → 357

MIH1; Mitotic inducer, protein phosphatase [Cell division and chromosome partitioning]

cl00125
Location:204 → 337

RHOD; Rhodanese Homology Domain (RHOD); an alpha beta fold domain found duplicated in the rhodanese protein. The cysteine containing enzymatically active version of the domain is also found in the Cdc25 class of protein phosphatases and a variety of proteins ...