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dnajc10 DnaJ (Hsp40) homolog, subfamily C, member 10 [ Danio rerio (zebrafish) ]

Gene ID: 557858, updated on 27-Mar-2024

Summary

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Official Symbol
dnajc10provided by ZNC
Official Full Name
DnaJ (Hsp40) homolog, subfamily C, member 10provided by ZNC
Primary source
ZFIN:ZDB-GENE-070327-1
See related
Ensembl:ENSDARG00000074727 AllianceGenome:ZFIN:ZDB-GENE-070327-1
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Danio rerio
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
Also known as
zgc:162218
Summary
Predicted to enable oxidoreductase activity. Predicted to be located in endoplasmic reticulum. Orthologous to human DNAJC10 (DnaJ heat shock protein family (Hsp40) member C10). [provided by Alliance of Genome Resources, Apr 2022]
Orthologs
human mouse all
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Genomic context

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Location:
chromosome: 9
Exon count:
23
Annotation release Status Assembly Chr Location
106 current GRCz11 (GCF_000002035.6) 9 NC_007120.7 (44870459..44897503, complement)
105 previous assembly GRCz10 (GCF_000002035.5) 9 NC_007120.6 (45069507..45096551, complement)

Chromosome 9 - NC_007120.7Genomic Context describing neighboring genes Neighboring gene NCK-associated protein 1 Neighboring gene frizzled related protein Neighboring gene zgc:66484 Neighboring gene villin 1

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • BioProject: PRJEB1986
  • Analysis date: Fri Dec 8 19:48:10 2017

Bibliography

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Related articles in PubMed

  1. MicroRNA-3906 regulates fast muscle differentiation through modulating the target gene homer-1b in zebrafish embryos. Lin CY, et al. PLoS One, 2013. PMID 23936160, Free PMC Article
  2. CERKL knockdown causes retinal degeneration in zebrafish. Riera M, et al. PLoS One, 2013. PMID 23671706, Free PMC Article
  3. Evolution of complexity in the zebrafish synapse proteome. Bayés À, et al. Nat Commun, 2017 Mar 2. PMID 28252024, Free PMC Article
  4. RFX transcription factors are essential for hearing in mice. Elkon R, et al. Nat Commun, 2015 Oct 15. PMID 26469318, Free PMC Article
  5. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article

See all (7) citations in PubMed

GeneRIFs: Gene References Into Functions

General gene information

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Markers

Homology

Clone Names

  • MGC162218

Gene Ontology Provided by ZFIN

Function Evidence Code Pubs
enables misfolded protein binding IBA
Inferred from Biological aspect of Ancestor
more info
  
enables oxidoreductase activity IEA
Inferred from Electronic Annotation
more info
  
enables oxidoreductase activity, acting on a sulfur group of donors, disulfide as acceptor IBA
Inferred from Biological aspect of Ancestor
more info
  
enables protein-disulfide reductase activity IBA
Inferred from Biological aspect of Ancestor
more info
  
Process Evidence Code Pubs
involved_in IRE1-mediated unfolded protein response IBA
Inferred from Biological aspect of Ancestor
more info
  
Component Evidence Code Pubs
is_active_in endoplasmic reticulum lumen IBA
Inferred from Biological aspect of Ancestor
more info
  

General protein information

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Preferred Names
dnaJ homolog subfamily C member 10
NP_001077016.1

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001083547.1 → NP_001077016.1  dnaJ homolog subfamily C member 10

    See identical proteins and their annotated locations for NP_001077016.1

    Status: PROVISIONAL

    Source sequence(s)
    BC134925
    UniProtKB/TrEMBL
    A0A8M1NCC7, A4IG47
    Related
    ENSDARP00000103524.2, ENSDART00000110697.3
    Conserved Domains (7) summary
    COG0484
    Location:33 → 129
    DnaJ; DnaJ-class molecular chaperone with C-terminal Zn finger domain [Posttranslational modification, protein turnover, chaperones]
    cd02961
    Location:348 → 443
    PDI_a_family; Protein Disulfide Isomerase (PDIa) family, redox active TRX domains; composed of eukaryotic proteins involved in oxidative protein folding in the endoplasmic reticulum (ER) by acting as catalysts and folding assistants. Members of this family include PDI ...
    cd03003
    Location:128 → 228
    PDI_a_ERdj5_N; PDIa family, N-terminal ERdj5 subfamily; ERdj5, also known as JPDI and macrothioredoxin, is a protein containing an N-terminal DnaJ domain and four redox active TRX domains. This subfamily is comprised of the first TRX domain of ERdj5 located after the ...
    cd03004
    Location:552 → 660
    PDI_a_ERdj5_C; PDIa family, C-terminal ERdj5 subfamily; ERdj5, also known as JPDI and macrothioredoxin, is a protein containing an N-terminal DnaJ domain and four redox active TRX domains. This subfamily is composed of the three TRX domains located at the C-terminal ...
    TIGR01130
    Location:129 → 648
    ER_PDI_fam; protein disulfide isomerase, eukaryotic
    pfam00226
    Location:33 → 95
    DnaJ; DnaJ domain
    cl00388
    Location:276 → 318
    Thioredoxin_like; Protein Disulfide Oxidoreductases and Other Proteins with a Thioredoxin fold

RefSeqs of Annotated Genomes: Danio rerio Annotation Release 106 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCz11 Primary Assembly

Genomic

  1. NC_007120.7 Reference GRCz11 Primary Assembly

    Range
    44870459..44897503 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
Nucleotide Protein
Heading Accession and Version

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