zcrb1 zinc finger CCHC-type and RNA binding motif 1 [Danio rerio (zebrafish)] - Gene

Summary

Official Symbol: zcrb1provided by ZNC
Official Full Name: zinc finger CCHC-type and RNA binding motif 1provided by ZNC
Primary source: ZFIN:ZDB-GENE-041210-114
See related: Ensembl:ENSDARG00000045691 AllianceGenome:ZFIN:ZDB-GENE-041210-114
Gene type: protein coding
RefSeq status: VALIDATED
Organism: Danio rerio
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
Also known as: zgc:110711; si:ch211-155a11.4
Summary: Predicted to enable RNA binding activity and zinc ion binding activity. Predicted to be involved in mRNA splicing, via spliceosome. Predicted to act upstream of or within RNA splicing and mRNA processing. Predicted to be located in nucleus. Predicted to be part of U12-type spliceosomal complex. Orthologous to human ZCRB1 (zinc finger CCHC-type and RNA binding motif containing 1). [provided by Alliance of Genome Resources, Apr 2022]
Orthologs: human mouse all
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Genomic context

Location:: chromosome: 4

Exon count:: 8

Annotation release	Status	Assembly	Chr	Location
106	current	GRCz11 (GCF_000002035.6)	4	NC_007115.7 (13925287..13931515, complement)
105	previous assembly	GRCz10 (GCF_000002035.5)	4	NC_007115.6 (13926438..13932666, complement)

Chromosome 4 - NC_007115.7 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

Expression

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See details

Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
BioProject: PRJEB1986
Analysis date: Fri Dec 8 19:48:10 2017

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

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General gene information

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Gene Ontology Provided by ZFIN

Function	Evidence Code	Pubs
enables RNA binding	IEA Inferred from Electronic Annotation more info
enables metal ion binding	IEA Inferred from Electronic Annotation more info
enables nucleic acid binding	IEA Inferred from Electronic Annotation more info
enables zinc ion binding	IEA Inferred from Electronic Annotation more info

Process	Evidence Code	Pubs
acts_upstream_of_or_within RNA splicing	IEA Inferred from Electronic Annotation more info
acts_upstream_of_or_within mRNA processing	IEA Inferred from Electronic Annotation more info
acts_upstream_of_or_within mRNA splicing, via spliceosome	IEA Inferred from Electronic Annotation more info

Component	Evidence Code	Pubs
part_of U12-type spliceosomal complex	IBA Inferred from Biological aspect of Ancestor more info
part_of U12-type spliceosomal complex	IEA Inferred from Electronic Annotation more info
located_in nucleus	IEA Inferred from Electronic Annotation more info
part_of spliceosomal complex	IEA Inferred from Electronic Annotation more info

General protein information

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Preferred Names: zinc finger CCHC-type and RNA-binding motif-containing protein 1

Names: U11/U12 small nuclear ribonucleoprotein 31 kDa protein; U11/U12 snRNP 31 kDa protein

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

NM_001017589.2 → NP_001017589.2 zinc finger CCHC-type and RNA-binding motif-containing protein 1

See identical proteins and their annotated locations for NP_001017589.2

Status: VALIDATED

Source sequence(s)

AL929504, EH551637, EH573039

UniProtKB/Swiss-Prot

Q567W3, Q5SP50

Related

ENSDARP00000067173.3, ENSDART00000067174.4

Conserved Domains (3) summary

COG0724
Location:7 → 106

RRM; RNA recognition motif (RRM) domain [Translation, ribosomal structure and biogenesis]

cd12393
Location:9 → 86

RRM_ZCRB1; RNA recognition motif in Zinc finger CCHC-type and RNA-binding motif-containing protein 1 (ZCRB1) and similar proteins

pfam00098
Location:106 → 122

zf-CCHC; Zinc knuckle