KPNA3 karyopherin subunit alpha 3 [Bos taurus (cattle)] - Gene

Summary

Official Symbol: KPNA3provided by VGNC
Official Full Name: karyopherin subunit alpha 3provided by VGNC
Primary source: VGNC:VGNC:30702
See related: BGD:BT15109; Ensembl:ENSBTAG00000004850
Gene type: protein coding
RefSeq status: VALIDATED
Organism: Bos taurus
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Artiodactyla; Ruminantia; Pecora; Bovidae; Bovinae; Bos
Annotation information: Annotation category: suggests misassembly
Orthologs: human mouse all
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Genomic context

Location:: chromosome: 12

Exon count:: 17

Annotation release	Status	Assembly	Chr	Location
RS_2023_09	current	ARS-UCD2.0 (GCF_002263795.3)	12	NC_037339.1 (19241567..19339402, complement)

Chromosome 12 - NC_037339.1 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Go to reference sequence details

Genomic Sequence:: NC_037339.1 Chromosome 12 Reference ARS-UCD2.0 Primary Assembly

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

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General gene information

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Markers

G43604 (e-PCR)
- UniSTS:95039

D13S663E (e-PCR)
- UniSTS:153194

RH103323 (e-PCR)
- UniSTS:97654

MARC_17027-17028:1023293711:3 (e-PCR)
- UniSTS:268189

MARC_17027-17028:1032295869:3 (e-PCR)
- UniSTS:268189

KPNA3 (e-PCR)
- UniSTS:505312

KPNA3_1525 (e-PCR)
- UniSTS:462306

KPNA3_v515 (e-PCR)
- UniSTS:462306

Gene Ontology Provided by RefSeq

Function	Evidence Code	Pubs
enables nuclear import signal receptor activity	IEA Inferred from Electronic Annotation more info	PubMed
enables nuclear localization sequence binding	IEA Inferred from Electronic Annotation more info	PubMed
enables protein binding	IEA Inferred from Electronic Annotation more info	PubMed

Process	Evidence Code	Pubs
involved_in NLS-bearing protein import into nucleus	IEA Inferred from Electronic Annotation more info	PubMed

Component	Evidence Code	Pubs
located_in cytoplasm	IEA Inferred from Electronic Annotation more info	PubMed
located_in nucleoplasm	IEA Inferred from Electronic Annotation more info	PubMed
located_in nucleus	IEA Inferred from Electronic Annotation more info	PubMed

General protein information

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Preferred Names: importin subunit alpha-4

Names: karyopherin alpha 3 (importin alpha 4)

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

NM_001192773.3 → NP_001179702.3 importin subunit alpha-4

Status: VALIDATED

Source sequence(s)

NKLS02000012

UniProtKB/TrEMBL

A0A3Q1MUS6, F1MIZ9

Related

ENSBTAP00000072854.2, ENSBTAT00000080687.2

Conserved Domains (2) summary

COG5064
Location:7 → 521

SRP1; Karyopherin (importin) alpha [Intracellular trafficking and secretion]

sd00043
Location:244 → 269

ARM; armadillo repeat [structural motif]

RefSeqs of Annotated Genomes: GCF_002263795.3-RS_2023_09

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference ARS-UCD2.0 Primary Assembly

Genomic

NC_037339.1 Reference ARS-UCD2.0 Primary Assembly

Range

19241567..19339402 complement

Download

GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

XM_024999948.2 → XP_024855716.1 importin subunit alpha-4 isoform X1

UniProtKB/TrEMBL

A0A3Q1NKI3, F1MIZ9

Conserved Domains (2) summary

COG5064
Location:1 → 497

SRP1; Karyopherin (importin) alpha [Intracellular trafficking and secretion]

sd00043
Location:220 → 245

ARM; armadillo repeat [structural motif]