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PKN2 protein kinase N2 [ Bos taurus (cattle) ]

Gene ID: 519754, updated on 5-Mar-2024

Summary

Official Symbol
PKN2provided by VGNC
Official Full Name
protein kinase N2provided by VGNC
Primary source
VGNC:VGNC:32946
See related
BGD:BT14705; Ensembl:ENSBTAG00000021900
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Bos taurus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Artiodactyla; Ruminantia; Pecora; Bovidae; Bovinae; Bos
Orthologs
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Genomic context

See PKN2 in Genome Data Viewer
Location:
chromosome: 3
Exon count:
22
Annotation release Status Assembly Chr Location
RS_2023_09 current ARS-UCD2.0 (GCF_002263795.3) 3 NC_037330.1 (55055201..55200939, complement)

Chromosome 3 - NC_037330.1Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC104971647 Neighboring gene kynurenine aminotransferase 3 Neighboring gene general transcription factor IIB Neighboring gene tigger transposable element-derived protein 1-like Neighboring gene uncharacterized LOC132345001

Genomic regions, transcripts, and products

Genomic Sequence:
NC_037330.1 Chromosome 3 Reference ARS-UCD2.0 Primary Assembly

General protein information

Preferred Names
serine/threonine-protein kinase N2
NP_001180171.1
XP_010801605.1
XP_024844740.1

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001193242.1NP_001180171.1  serine/threonine-protein kinase N2

    See identical proteins and their annotated locations for NP_001180171.1

    Status: PROVISIONAL

    Source sequence(s)
    NKLS02000003
    UniProtKB/TrEMBL
    A0A3Q1LZH0, F1MFK1
    Related
    ENSBTAP00000029201.6, ENSBTAT00000029201.7
    Conserved Domains (6) summary
    cd08687
    Location:389472
    C2_PKN-like; C2 domain in Protein kinase C-like (PKN) proteins
    cd11622
    Location:42107
    HR1_PKN_1; First Protein kinase C-related kinase homology region 1 (HR1) Rho-binding domain of Protein Kinase N
    cd11631
    Location:128201
    HR1_PKN2_2; Second Protein kinase C-related kinase homology region 1 (HR1) Rho-binding domain of Protein Kinase N2
    cd11635
    Location:209282
    HR1_PKN2_3; Third Protein kinase C-related kinase homology region 1 (HR1) Rho-binding domain of Protein Kinase N2
    smart00220
    Location:659913
    S_TKc; Serine/Threonine protein kinases, catalytic domain
    cd05589
    Location:654979
    STKc_PKN; Catalytic domain of the Serine/Threonine Kinase, Protein Kinase N

RefSeqs of Annotated Genomes: GCF_002263795.3-RS_2023_09

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference ARS-UCD2.0 Primary Assembly

Genomic

  1. NC_037330.1 Reference ARS-UCD2.0 Primary Assembly

    Range
    55055201..55200939 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_010803303.4XP_010801605.1  serine/threonine-protein kinase N2 isoform X1

    UniProtKB/TrEMBL
    A0A3Q1LZH0, A0A3Q1M4E8
    Conserved Domains (6) summary
    cd11622
    Location:42107
    HR1_PKN_1; First Protein kinase C-related kinase homology region 1 (HR1) Rho-binding domain of Protein Kinase N
    cd11635
    Location:209282
    HR1_PKN2_3; Third Protein kinase C-related kinase homology region 1 (HR1) Rho-binding domain of Protein Kinase N2
    smart00220
    Location:611865
    S_TKc; Serine/Threonine protein kinases, catalytic domain
    cd05589
    Location:606931
    STKc_PKN; Catalytic domain of the Serine/Threonine Kinase, Protein Kinase N
    cl00087
    Location:128201
    HR1; Protein kinase C-related kinase homology region 1 (HR1) domain that binds Rho family small GTPases
    cl14603
    Location:389471
    C2; C2 domain
  2. XM_024988972.2XP_024844740.1  serine/threonine-protein kinase N2 isoform X2

    UniProtKB/TrEMBL
    A0A3Q1LZH0
    Conserved Domains (4) summary
    cd08687
    Location:251334
    C2_PKN-like; C2 domain in Protein kinase C-like (PKN) proteins
    cd11635
    Location:71144
    HR1_PKN2_3; Third Protein kinase C-related kinase homology region 1 (HR1) Rho-binding domain of Protein Kinase N2
    cd05589
    Location:516841
    STKc_PKN; Catalytic domain of the Serine/Threonine Kinase, Protein Kinase N
    cl00087
    Location:163
    HR1; Protein kinase C-related kinase homology region 1 (HR1) domain that binds Rho family small GTPases