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L3MBTL2 L3MBTL histone methyl-lysine binding protein 2 [ Bos taurus (cattle) ]

Gene ID: 513297, updated on 3-Apr-2024

Summary

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Official Symbol
L3MBTL2provided by VGNC
Official Full Name
L3MBTL histone methyl-lysine binding protein 2provided by VGNC
Primary source
VGNC:VGNC:30763
See related
BGD:BT18629; Ensembl:ENSBTAG00000030222
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Bos taurus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Artiodactyla; Ruminantia; Pecora; Bovidae; Bovinae; Bos
Orthologs
human mouse all
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Genomic context

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Location:
chromosome: 5
Exon count:
19
Annotation release Status Assembly Chr Location
RS_2023_09 current ARS-UCD2.0 (GCF_002263795.3) 5 NC_037332.1 (112362253..112383952)

Chromosome 5 - NC_037332.1Genomic Context describing neighboring genes Neighboring gene microRNA mir-1281 Neighboring gene E1A binding protein p300 Neighboring gene uncharacterized LOC112446777 Neighboring gene microRNA mir-2441 Neighboring gene chondroadherin like Neighboring gene Ran GTPase activating protein 1 Neighboring gene zinc finger CCCH-type containing 7B

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_037332.1 Chromosome 5 Reference ARS-UCD2.0 Primary Assembly

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Sequence evaluation of four pooled-tissue normalized bovine cDNA libraries and construction of a gene index for cattle. Smith TP, et al. Genome Res, 2001 Apr. PMID 11282978, Free PMC Article
  2. Characterization of 954 bovine full-CDS cDNA sequences. Harhay GP, et al. BMC Genomics, 2005 Nov 23. PMID 16305752, Free PMC Article
  3. A whole-genome assembly of the domestic cow, Bos taurus. Zimin AV, et al. Genome Biol, 2009. PMID 19393038, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Markers

Homology

Clone Names

  • MGC139186

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables methylated histone binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables zinc ion binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in regulation of DNA-templated transcription IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in nucleus IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
lethal(3)malignant brain tumor-like protein 2
Names
L3MBTL2, polycomb repressive complex 1 subunit
l(3)mbt-like 2 protein
l(3)mbt-like protein 2
lethal(3)malignant brain tumor-like 2 protein

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001075610.1 → NP_001069078.1  lethal(3)malignant brain tumor-like protein 2

    See identical proteins and their annotated locations for NP_001069078.1

    Status: PROVISIONAL

    Source sequence(s)
    BC116013
    UniProtKB/Swiss-Prot
    Q0V8P8, Q1JQD9
    UniProtKB/TrEMBL
    A0A3Q1MDJ1
    Related
    ENSBTAP00000037474.5, ENSBTAT00000037648.5
    Conserved Domains (2) summary
    smart00561
    Location:512 → 605
    MBT; Present in Drosophila Scm, l(3)mbt, and vertebrate SCML2
    pfam02820
    Location:434 → 501
    MBT; mbt repeat

RefSeqs of Annotated Genomes: GCF_002263795.3-RS_2023_09

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference ARS-UCD2.0 Primary Assembly

Genomic

  1. NC_037332.1 Reference ARS-UCD2.0 Primary Assembly

    Range
    112362253..112383952
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_059886330.1 → XP_059742313.1  lethal(3)malignant brain tumor-like protein 2 isoform X2

  2. XM_059886328.1 → XP_059742311.1  lethal(3)malignant brain tumor-like protein 2 isoform X1

    Related
    ENSBTAP00000072805.2, ENSBTAT00000085264.2

  3. XM_059886329.1 → XP_059742312.1  lethal(3)malignant brain tumor-like protein 2 isoform X2

  4. XM_005207391.5 → XP_005207448.1  lethal(3)malignant brain tumor-like protein 2 isoform X3

    Conserved Domains (2) summary
    smart00561
    Location:512 → 605
    MBT; Present in Drosophila Scm, l(3)mbt, and vertebrate SCML2
    pfam02820
    Location:434 → 501
    MBT; mbt repeat
Nucleotide Protein Strain
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q1JQD9.1 GenPept UniProtKB/Swiss-Prot:Q1JQD9

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