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LGALS9 galectin 9 [ Bos taurus (cattle) ]

Gene ID: 510813, updated on 16-Jan-2024

Summary

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Gene symbol
LGALS9
Gene description
galectin 9
See related
BGD:BT11546; Ensembl:ENSBTAG00000006846
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Bos taurus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Artiodactyla; Ruminantia; Pecora; Bovidae; Bovinae; Bos
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Genomic context

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See LGALS9 in Genome Data Viewer
Location:
chromosome: 19
Exon count:
11
Annotation release Status Assembly Chr Location
RS_2023_09 current ARS-UCD2.0 (GCF_002263795.3) 19 NC_037346.1 (19368423..19387201)

Chromosome 19 - NC_037346.1Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC100848006 Neighboring gene galectin-9-like Neighboring gene nitric oxide synthase 2 Neighboring gene uncharacterized LOC132343024 Neighboring gene LYR motif containing 9

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_037346.1 Chromosome 19 Reference ARS-UCD2.0 Primary Assembly

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Increased bovine Tim-3 and its ligand expressions during bovine leukemia virus infection. Okagawa T, et al. Vet Res, 2012 May 23. PMID 22621175, Free PMC Article
  2. Endometrial expression of progesterone-induced blocking factor and galectins-1, -3, -9, and -3 binding protein in the luteal phase and early pregnancy in cattle. Okumu LA, et al. Physiol Genomics, 2011 Jul 27. PMID 21610087
  3. Analysis of bovine mammary gland EST and functional annotation of the Bos taurus gene index. Sonstegard TS, et al. Mamm Genome, 2002 Jul. PMID 12140684
  4. Sequence evaluation of four pooled-tissue normalized bovine cDNA libraries and construction of a gene index for cattle. Smith TP, et al. Genome Res, 2001 Apr. PMID 11282978, Free PMC Article
  5. Characterization of 954 bovine full-CDS cDNA sequences. Harhay GP, et al. BMC Genomics, 2005 Nov 23. PMID 16305752, Free PMC Article

See all (7) citations in PubMed

GeneRIFs: Gene References Into Functions

What's a GeneRIF?
  1. The Tim-3/Gal-9 pathway might link disease progression with T cell exhaustion during bovine leukemia virus infection.
    Title: Increased bovine Tim-3 and its ligand expressions during bovine leukemia virus infection.
  2. The relative abundance of PIBF, LGALS1, LGALS3, LGALS3BP, and LGALS9 mRNA would display a differential expression pattern in the endometrium.
    Title: Endometrial expression of progesterone-induced blocking factor and galectins-1, -3, -9, and -3 binding protein in the luteal phase and early pregnancy in cattle.
Submit: New GeneRIF Correction

General gene information

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Homology

Clone Names

  • MGC129126

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables carbohydrate binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables galactoside binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in negative regulation of CD4-positive, alpha-beta T cell proliferation IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in negative regulation of type II interferon production IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in positive regulation of gene expression IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in cytosol IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in nucleus IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
galectin-9
Names
gal-9
lectin, galactoside-binding, soluble, 9 (galectin 9)

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001015570.3 → NP_001015570.1  galectin-9 isoform 2

    See identical proteins and their annotated locations for NP_001015570.1

    Status: VALIDATED

    Source sequence(s)
    AW466029, BE753823, BT020980
    UniProtKB/Swiss-Prot
    Q3MHZ8
    UniProtKB/TrEMBL
    Q5E9E0
    Related
    ENSBTAP00000009005.3, ENSBTAT00000009005.5
    Conserved Domains (2) summary
    smart00908
    Location:22 → 146
    Gal-bind_lectin; Galactoside-binding lectin
    cd00070
    Location:194 → 322
    GLECT; Galectin/galactose-binding lectin. This domain exclusively binds beta-galactosides, such as lactose, and does not require metal ions for activity. GLECT domains occur as homodimers or tandemly repeated domains. They are developmentally regulated and may ...

  2. NM_001039177.2 → NP_001034266.1  galectin-9 isoform 1

    See identical proteins and their annotated locations for NP_001034266.1

    Status: VALIDATED

    Source sequence(s)
    AW466029, BC104505, BE753823
    UniProtKB/Swiss-Prot
    Q3MHZ8
    UniProtKB/TrEMBL
    F1MZ12
    Related
    ENSBTAP00000009025.5, ENSBTAT00000009025.6
    Conserved Domains (2) summary
    smart00908
    Location:22 → 146
    Gal-bind_lectin; Galactoside-binding lectin
    cd00070
    Location:226 → 354
    GLECT; Galectin/galactose-binding lectin. This domain exclusively binds beta-galactosides, such as lactose, and does not require metal ions for activity. GLECT domains occur as homodimers or tandemly repeated domains. They are developmentally regulated and may ...

RefSeqs of Annotated Genomes: GCF_002263795.3-RS_2023_09

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference ARS-UCD2.0 Primary Assembly

Genomic

  1. NC_037346.1 Reference ARS-UCD2.0 Primary Assembly

    Range
    19368423..19387201
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_024979912.2 → XP_024835680.1  galectin-9 isoform X1

    UniProtKB/Swiss-Prot
    Q3MHZ8
    Conserved Domains (1) summary
    cd00070
    Location:157 → 285
    GLECT; Galectin/galactose-binding lectin. This domain exclusively binds beta-galactosides, such as lactose, and does not require metal ions for activity. GLECT domains occur as homodimers or tandemly repeated domains. They are developmentally regulated and may ...

  2. XM_024979913.2 → XP_024835681.1  galectin-9 isoform X2

    Conserved Domains (1) summary
    smart00908
    Location:22 → 146
    Gal-bind_lectin; Galactoside-binding lectin
Nucleotide Protein Strain
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q3MHZ8.1 GenPept UniProtKB/Swiss-Prot:Q3MHZ8

Gene LinkOut

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