CMTR1 cap methyltransferase 1 [Bos taurus (cattle)] - Gene

Summary

Official Symbol: CMTR1provided by VGNC
Official Full Name: cap methyltransferase 1provided by VGNC
Primary source: VGNC:VGNC:27489
See related: BGD:BT21414; Ensembl:ENSBTAG00000017091
Gene type: protein coding
RefSeq status: PROVISIONAL
Organism: Bos taurus
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Artiodactyla; Ruminantia; Pecora; Bovidae; Bovinae; Bos
Also known as: MTr1; FTSJD2
Orthologs: human mouse all
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Genomic context

Location:: chromosome: 23

Exon count:: 24

Annotation release	Status	Assembly	Chr	Location
RS_2023_09	current	ARS-UCD2.0 (GCF_002263795.3)	23	NC_037350.1 (11318812..11371568)

Chromosome 23 - NC_037350.1 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:: NC_037350.1 Chromosome 23 Reference ARS-UCD2.0 Primary Assembly

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

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General gene information

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Markers

MARC_12161-12162:1004709416:1 (e-PCR)
- UniSTS:267349

MARC_12161-12162:1007742787:1 (e-PCR)
- UniSTS:267349

MARC_15695-15696:1013523466:1 (e-PCR)
- UniSTS:267870

MARC_23451-23452:1027106806:1 (e-PCR)
- UniSTS:268702

Gene Ontology Provided by RefSeq

Function	Evidence Code	Pubs
enables mRNA (nucleoside-2'-O-)-methyltransferase activity	IEA Inferred from Electronic Annotation more info	PubMed
enables nucleic acid binding	IEA Inferred from Electronic Annotation more info	PubMed
enables protein binding	IEA Inferred from Electronic Annotation more info	PubMed

Process	Evidence Code	Pubs
involved_in 7-methylguanosine mRNA capping	IEA Inferred from Electronic Annotation more info	PubMed

Component	Evidence Code	Pubs
located_in cytoplasm	IEA Inferred from Electronic Annotation more info	PubMed
located_in nucleus	IEA Inferred from Electronic Annotation more info	PubMed

General protein information

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Preferred Names: cap-specific mRNA (nucleoside-2'-O-)-methyltransferase 1

Names: FtsJ methyltransferase domain containing 2; cap1 2'O-ribose methyltransferase 1; ftsJ methyltransferase domain-containing protein 2

NP_001075899.1

EC 2.1.1.57

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

NM_001082430.2 → NP_001075899.1 cap-specific mRNA (nucleoside-2'-O-)-methyltransferase 1

See identical proteins and their annotated locations for NP_001075899.1

Status: PROVISIONAL

Source sequence(s)

BC133559

UniProtKB/Swiss-Prot

A2VE39

UniProtKB/TrEMBL

A0A3Q1LYF0

Related

ENSBTAP00000022726.6, ENSBTAT00000022726.7

Conserved Domains (4) summary

smart00456
Location:753 → 786

WW; Domain with 2 conserved Trp (W) residues

pfam01585
Location:87 → 129

G-patch; G-patch domain

pfam01728
Location:232 → 448

FtsJ; FtsJ-like methyltransferase

cl12015
Location:623 → 716

Adenylation_DNA_ligase_like; Adenylation domain of proteins similar to ATP-dependent polynucleotide ligases