SPARCL1 SPARC like 1 [Bos taurus (cattle)] - Gene

Summary

Official Symbol: SPARCL1provided by VGNC
Official Full Name: SPARC like 1provided by VGNC
Primary source: VGNC:VGNC:35172
See related: BGD:BT15171; Ensembl:ENSBTAG00000004094
Gene type: protein coding
RefSeq status: PROVISIONAL
Organism: Bos taurus
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Artiodactyla; Ruminantia; Pecora; Bovidae; Bovinae; Bos
Orthologs: human mouse all
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Genomic context

Location:: chromosome: 6

Exon count:: 11

Annotation release	Status	Assembly	Chr	Location
RS_2023_09	current	ARS-UCD2.0 (GCF_002263795.3)	6	NC_037333.1 (102370630..102423199, complement)

Chromosome 6 - NC_037333.1 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Go to reference sequence details

Genomic Sequence:: NC_037333.1 Chromosome 6 Reference ARS-UCD2.0 Primary Assembly

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

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General gene information

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Markers

BZ944321 (e-PCR)
- UniSTS:475464

SPARCL1 (e-PCR)
- UniSTS:279130

Gene Ontology Provided by RefSeq

Function	Evidence Code	Pubs
enables calcium ion binding	IEA Inferred from Electronic Annotation more info	PubMed
enables collagen binding	IEA Inferred from Electronic Annotation more info	PubMed
enables extracellular matrix binding	IEA Inferred from Electronic Annotation more info	PubMed
enables protein binding	IEA Inferred from Electronic Annotation more info	PubMed

Process	Evidence Code	Pubs
involved_in anatomical structure development	IEA Inferred from Electronic Annotation more info	PubMed
involved_in signal transduction	IEA Inferred from Electronic Annotation more info	PubMed

Component	Evidence Code	Pubs
located_in collagen-containing extracellular matrix	IEA Inferred from Electronic Annotation more info	PubMed
located_in extracellular space	IEA Inferred from Electronic Annotation more info	PubMed

General protein information

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Preferred Names: SPARC-like protein 1

Names: SPARC-like 1 (hevin); SPARC-like 1 (mast9, hevin)

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

NM_001034302.2 → NP_001029474.1 SPARC-like protein 1 precursor

See identical proteins and their annotated locations for NP_001029474.1

Status: PROVISIONAL

Source sequence(s)

BC103351

UniProtKB/TrEMBL

A0A3Q1LIS3, Q3SYW7

Related

ENSBTAP00000005348.2, ENSBTAT00000005348.3

Conserved Domains (4) summary

cd00252
Location:504 → 652

SPARC_EC; SPARC_EC; extracellular Ca2+ binding domain (containing 2 EF-hand motifs) of SPARC and related proteins (QR1, SC1/hevin, testican and tsc-36/FRP). SPARC (BM-40) is a multifunctional glycoprotein, a matricellular protein, that functions to regulate ...

pfam05029
Location:32 → 277

TIMELESS_C; Timeless protein C terminal region

pfam10591
Location:503 → 638

SPARC_Ca_bdg; Secreted protein acidic and rich in cysteine Ca binding region

cl00097
Location:423 → 502

KAZAL_FS; Kazal type serine protease inhibitors and follistatin-like domains. Kazal inhibitors inhibit serine proteases, such as, trypsin, chyomotrypsin, avian ovomucoids, and elastases. The inhibitory domain has one reactive site peptide bond, which serves the ...