fgf18b fibroblast growth factor 18b [Danio rerio (zebrafish)] - Gene

Summary

Official Symbol: fgf18bprovided by ZNC
Official Full Name: fibroblast growth factor 18bprovided by ZNC
Primary source: ZFIN:ZDB-GENE-050221-4
See related: Ensembl:ENSDARG00000043962 AllianceGenome:ZFIN:ZDB-GENE-050221-4
Gene type: protein coding
RefSeq status: PROVISIONAL
Organism: Danio rerio
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
Also known as: fgf18l
Summary: Predicted to enable growth factor activity; type 1 fibroblast growth factor receptor binding activity; and type 2 fibroblast growth factor receptor binding activity. Predicted to be involved in several processes, including fibroblast growth factor receptor signaling pathway; positive regulation of cell population proliferation; and positive regulation of macromolecule metabolic process. Predicted to be located in extracellular region. Predicted to be active in cytoplasm and extracellular space. Is expressed in several structures, including heart; midbrain hindbrain boundary; otic vesicle; pharyngeal arch; and sensory system. Orthologous to human FGF18 (fibroblast growth factor 18). [provided by Alliance of Genome Resources, Apr 2022]
Orthologs: all
NEW: Try the new Gene table
Try the new Transcript table

Genomic context

Location:: chromosome: 10

Exon count:: 5

Annotation release	Status	Assembly	Chr	Location
106	current	GRCz11 (GCF_000002035.6)	10	NC_007121.7 (21470327..21484065, complement)
105	previous assembly	GRCz10 (GCF_000002035.5)	10	NC_007121.6 (21517064..21527181, complement)

Chromosome 10 - NC_007121.7 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

Go to the top of the page Help

Go to reference sequence details

Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

Expression

Go to the top of the page Help

See details

Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
BioProject: PRJEB1986
Analysis date: Fri Dec 8 19:48:10 2017

Bibliography

Go to the top of the page Help

GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Submit: New GeneRIF Correction

General gene information

Go to the top of the page Help

Gene Ontology Provided by ZFIN

Function	Evidence Code	Pubs
enables growth factor activity	IBA Inferred from Biological aspect of Ancestor more info
enables growth factor activity	IEA Inferred from Electronic Annotation more info
enables type 1 fibroblast growth factor receptor binding	IBA Inferred from Biological aspect of Ancestor more info
enables type 2 fibroblast growth factor receptor binding	IBA Inferred from Biological aspect of Ancestor more info

Process	Evidence Code	Pubs
involved_in animal organ morphogenesis	IBA Inferred from Biological aspect of Ancestor more info
involved_in cell differentiation	IBA Inferred from Biological aspect of Ancestor more info
involved_in fibroblast growth factor receptor signaling pathway	IBA Inferred from Biological aspect of Ancestor more info
involved_in positive regulation of MAPK cascade	IBA Inferred from Biological aspect of Ancestor more info
involved_in positive regulation of cell population proliferation	IBA Inferred from Biological aspect of Ancestor more info
involved_in positive regulation of gene expression	IBA Inferred from Biological aspect of Ancestor more info
involved_in positive regulation of protein phosphorylation	IBA Inferred from Biological aspect of Ancestor more info
involved_in regulation of cell migration	IBA Inferred from Biological aspect of Ancestor more info

Component	Evidence Code	Pubs
is_active_in cytoplasm	IBA Inferred from Biological aspect of Ancestor more info
located_in extracellular region	IEA Inferred from Electronic Annotation more info
is_active_in extracellular space	IBA Inferred from Biological aspect of Ancestor more info

General protein information

Go to the top of the page Help

Preferred Names: fibroblast growth factor 18b

Names: fibroblast growth factor 18, like

NCBI Reference Sequences (RefSeq)

Go to the top of the page Help

NEW Try the new Transcript table

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

NM_001012379.1 → NP_001012379.1 fibroblast growth factor 18b precursor

See identical proteins and their annotated locations for NP_001012379.1

Status: PROVISIONAL

Source sequence(s)

AB195468

UniProtKB/TrEMBL

B3DIH2, Q5TKR7

Related

ENSDARP00000064544.5, ENSDART00000064545.6

Conserved Domains (1) summary

pfam00167
Location:53 → 176

FGF; Fibroblast growth factor

RefSeqs of Annotated Genomes: Danio rerio Annotation Release 106 details...

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCz11 Primary Assembly

Genomic

NC_007121.7 Reference GRCz11 Primary Assembly

Range

21470327..21484065 complement

Download

GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

XM_021479170.1 → XP_021334845.1 fibroblast growth factor 18b isoform X1

UniProtKB/TrEMBL

A0A8M9QKP6

Conserved Domains (1) summary

pfam00167
Location:6 → 96

FGF; Fibroblast growth factor