Gene description

bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase

Locus Tag

BURPS1106A_3398

Gene type

protein coding

RefSeq status

Provisional

Organism

Burkholderia pseudomallei 1106a

Lineage

Bacteria; Proteobacteria; Betaproteobacteria; Burkholderiales; Burkholderiaceae; Burkholderia; pseudomallei group

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Names

bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase

YP_001067635.1

EC 2.1.2.3

EC 3.5.4.10

involved in de novo purine biosynthesis

Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

This section includes genomic Reference Sequences (RefSeqs) from all assemblies on which this gene is annotated, such as RefSeqs for chromosomes and scaffolds (contigs) from both reference and alternate assemblies. Model RNAs and proteins are also reported here.

mRNA and Protein(s)

1. YP_001067635.1 bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase [Burkholderia pseudomallei 1106a]

   UniProtKB/Swiss-Prot

   A3NZ64

   Conserved Domains (3) summary

   cd01421
   Location:3 – 191
   Blast Score: 787

   IMPCH; Inosine monophosphate cyclohydrolase domain. This is the N-terminal domain in the purine biosynthesis pathway protein ATIC (purH). The bifunctional ATIC protein contains a C-terminal ATIC formylase domain that formylates 5-aminoimidazole-4-carboxamide...

   PRK00881
   Location:1 – 521
   Blast Score: 2567

   purH; bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase; Provisional

   cl03362
   Location:134 – 453
   Blast Score: 1352

   AICARFT_IMPCHas; AICARFT/IMPCHase bienzyme