U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

MFGE8 milk fat globule EGF and factor V/VIII domain containing [ Canis lupus familiaris (dog) ]

Gene ID: 488730, updated on 5-Mar-2024

Summary

Go to the top of the page Help
Official Symbol
MFGE8provided by VGNC
Official Full Name
milk fat globule EGF and factor V/VIII domain containingprovided by VGNC
Primary source
VGNC:VGNC:53186
See related
Ensembl:ENSCAFG00845003786
Gene type
protein coding
RefSeq status
MODEL
Organism
Canis lupus familiaris (sub-species: familiaris)
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Carnivora; Caniformia; Canidae; Canis
Orthologs
human mouse all
NEW
Try the new Gene table
Try the new Transcript table

Genomic context

Go to the top of the page Help
See MFGE8 in Genome Data Viewer
Location:
chromosome: 3
Exon count:
10
Annotation release Status Assembly Chr Location
106 current ROS_Cfam_1.0 (GCF_014441545.1) 3 NC_051807.1 (52473179..52499328, complement)
106 current Dog10K_Boxer_Tasha (GCF_000002285.5) 3 NC_006585.4 (54690614..54716666, complement)
106 current UU_Cfam_GSD_1.0 (GCF_011100685.1) 3 NC_049224.1 (52544955..52571161, complement)
106 current UMICH_Zoey_3.1 (GCF_005444595.1) 3 NC_049263.1 (51995688..52008715, complement)
106 current UNSW_CanFamBas_1.0 (GCF_013276365.1) 3 NC_049744.1 (52206149..52232464, complement)

Chromosome 3 - NC_051807.1Genomic Context describing neighboring genes Neighboring gene aggrecan Neighboring gene hyaluronan and proteoglycan link protein 3 Neighboring gene uncharacterized LOC119871204 Neighboring gene 40S ribosomal protein S2-like

Genomic regions, transcripts, and products

Go to the top of the page Help

Go to nucleotide: Graphics FASTA GenBank

Bibliography

Go to the top of the pageHelp

Related articles in PubMed

  1. Isolation of DNA markers informative in purebred dog families by genomic representational difference analysis (gRDA). Everts RE, et al. Mamm Genome, 2000 Sep. PMID 10967132

GeneRIFs: Gene References Into Functions

General gene information

Go to the top of the page Help

Markers

Homology

General protein information

Go to the top of the page Help
Preferred Names
lactadherin; LOW QUALITY PROTEIN: lactadherin
Names
milk fat globule-EGF factor 8 protein

NCBI Reference Sequences (RefSeq)

Go to the top of the page Help

NEW Try the new Transcript table

RefSeqs of Annotated Genomes: Canis lupus familiaris Annotation Release 106 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference ROS_Cfam_1.0

Genomic

  1. NC_051807.1 Reference ROS_Cfam_1.0

    Range
    52473179..52499328 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038661318.1 → XP_038517246.1  lactadherin isoform X3

    Conserved Domains (1) summary
    cd00057
    Location:162 → 316
    FA58C; Coagulation factor 5/8 C-terminal domain, discoidin domain; Cell surface-attached carbohydrate-binding domain, present in eukaryotes and assumed to have horizontally transferred to eubacterial genomes.

  2. XM_038661317.1 → XP_038517245.1  lactadherin isoform X2

    UniProtKB/TrEMBL
    A0A8I3RT41
    Conserved Domains (2) summary
    cd00054
    Location:26 → 61
    EGF_CA; Calcium-binding EGF-like domain, present in a large number of membrane-bound and extracellular (mostly animal) proteins. Many of these proteins require calcium for their biological function and calcium-binding sites have been found to be located at the ...
    cd00057
    Location:231 → 385
    FA58C; Coagulation factor 5/8 C-terminal domain, discoidin domain; Cell surface-attached carbohydrate-binding domain, present in eukaryotes and assumed to have horizontally transferred to eubacterial genomes.

  3. XM_038661316.1 → XP_038517244.1  lactadherin isoform X1

    UniProtKB/TrEMBL
    A0A8I3RT41
    Related
    ENSCAFP00845005382.1, ENSCAFT00845006768.1
    Conserved Domains (3) summary
    cd00054
    Location:26 → 61
    EGF_CA; Calcium-binding EGF-like domain, present in a large number of membrane-bound and extracellular (mostly animal) proteins. Many of these proteins require calcium for their biological function and calcium-binding sites have been found to be located at the ...
    cd00057
    Location:275 → 429
    FA58C; Coagulation factor 5/8 C-terminal domain, discoidin domain; Cell surface-attached carbohydrate-binding domain, present in eukaryotes and assumed to have horizontally transferred to eubacterial genomes.
    pfam00008
    Location:69 → 105
    EGF; EGF-like domain

Alternate UMICH_Zoey_3.1

Genomic

  1. NC_049263.1 Alternate UMICH_Zoey_3.1

    Range
    51995688..52008715 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038471887.1 → XP_038327815.1  LOW QUALITY PROTEIN: lactadherin isoform X1

Alternate UNSW_CanFamBas_1.0

Genomic

  1. NC_049744.1 Alternate UNSW_CanFamBas_1.0

    Range
    52206149..52232464 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038597136.1 → XP_038453064.1  lactadherin isoform X3

    Conserved Domains (1) summary
    cd00057
    Location:162 → 316
    FA58C; Coagulation factor 5/8 C-terminal domain, discoidin domain; Cell surface-attached carbohydrate-binding domain, present in eukaryotes and assumed to have horizontally transferred to eubacterial genomes.

  2. XM_038597135.1 → XP_038453063.1  lactadherin isoform X2

    Conserved Domains (2) summary
    cd00054
    Location:26 → 61
    EGF_CA; Calcium-binding EGF-like domain, present in a large number of membrane-bound and extracellular (mostly animal) proteins. Many of these proteins require calcium for their biological function and calcium-binding sites have been found to be located at the ...
    cd00057
    Location:231 → 385
    FA58C; Coagulation factor 5/8 C-terminal domain, discoidin domain; Cell surface-attached carbohydrate-binding domain, present in eukaryotes and assumed to have horizontally transferred to eubacterial genomes.

  3. XM_038597134.1 → XP_038453062.1  lactadherin isoform X1

Alternate UU_Cfam_GSD_1.0

Genomic

  1. NC_049224.1 Alternate UU_Cfam_GSD_1.0

    Range
    52544955..52571161 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038532812.1 → XP_038388740.1  lactadherin isoform X3

    Conserved Domains (1) summary
    cd00057
    Location:162 → 316
    FA58C; Coagulation factor 5/8 C-terminal domain, discoidin domain; Cell surface-attached carbohydrate-binding domain, present in eukaryotes and assumed to have horizontally transferred to eubacterial genomes.

  2. XM_038532811.1 → XP_038388739.1  lactadherin isoform X2

    UniProtKB/TrEMBL
    A0A8P0P7S2
    Conserved Domains (2) summary
    cd00054
    Location:26 → 61
    EGF_CA; Calcium-binding EGF-like domain, present in a large number of membrane-bound and extracellular (mostly animal) proteins. Many of these proteins require calcium for their biological function and calcium-binding sites have been found to be located at the ...
    cd00057
    Location:231 → 385
    FA58C; Coagulation factor 5/8 C-terminal domain, discoidin domain; Cell surface-attached carbohydrate-binding domain, present in eukaryotes and assumed to have horizontally transferred to eubacterial genomes.

  3. XM_038532810.1 → XP_038388738.1  lactadherin isoform X1

    UniProtKB/TrEMBL
    A0A8C0L2C7, A0A8C0M951, A0A8C0Q310

Alternate Dog10K_Boxer_Tasha Primary Assembly

Genomic

  1. NC_006585.4 Alternate Dog10K_Boxer_Tasha Primary Assembly

    Range
    54690614..54716666 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038474807.1 → XP_038330735.1  lactadherin isoform X3

    Conserved Domains (1) summary
    cd00057
    Location:162 → 316
    FA58C; Coagulation factor 5/8 C-terminal domain, discoidin domain; Cell surface-attached carbohydrate-binding domain, present in eukaryotes and assumed to have horizontally transferred to eubacterial genomes.

  2. XM_038474798.1 → XP_038330726.1  lactadherin isoform X2

    UniProtKB/TrEMBL
    A0A8P0P7S2
    Conserved Domains (2) summary
    cd00054
    Location:26 → 61
    EGF_CA; Calcium-binding EGF-like domain, present in a large number of membrane-bound and extracellular (mostly animal) proteins. Many of these proteins require calcium for their biological function and calcium-binding sites have been found to be located at the ...
    cd00057
    Location:231 → 385
    FA58C; Coagulation factor 5/8 C-terminal domain, discoidin domain; Cell surface-attached carbohydrate-binding domain, present in eukaryotes and assumed to have horizontally transferred to eubacterial genomes.

  3. XM_038474789.1 → XP_038330717.1  lactadherin isoform X1

    UniProtKB/TrEMBL
    A0A8P0P7S2
    Conserved Domains (2) summary
    cd00054
    Location:71 → 109
    EGF_CA; Calcium-binding EGF-like domain, present in a large number of membrane-bound and extracellular (mostly animal) proteins. Many of these proteins require calcium for their biological function and calcium-binding sites have been found to be located at the ...
    cd00057
    Location:275 → 429
    FA58C; Coagulation factor 5/8 C-terminal domain, discoidin domain; Cell surface-attached carbohydrate-binding domain, present in eukaryotes and assumed to have horizontally transferred to eubacterial genomes.
Nucleotide Protein
Heading Accession and Version

Gene LinkOut

The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.