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GABRG3 gamma-aminobutyric acid type A receptor subunit gamma3 [ Canis lupus familiaris (dog) ]

Gene ID: 488685, updated on 5-Mar-2024

Summary

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Official Symbol
GABRG3provided by VGNC
Official Full Name
gamma-aminobutyric acid type A receptor subunit gamma3provided by VGNC
Primary source
VGNC:VGNC:111506
See related
Ensembl:ENSCAFG00845017588
Gene type
protein coding
RefSeq status
MODEL
Organism
Canis lupus familiaris (sub-species: familiaris)
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Carnivora; Caniformia; Canidae; Canis
Orthologs
human mouse all
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Genomic context

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Location:
chromosome: 3
Exon count:
12
Annotation release Status Assembly Chr Location
106 current ROS_Cfam_1.0 (GCF_014441545.1) 3 NC_051807.1 (33293570..33977676, complement)
106 current Dog10K_Boxer_Tasha (GCF_000002285.5) 3 NC_006585.4 (35646875..36332262, complement)
106 current UU_Cfam_GSD_1.0 (GCF_011100685.1) 3 NC_049224.1 (33186801..33927787, complement)
106 current UMICH_Zoey_3.1 (GCF_005444595.1) 3 NC_049263.1 (32834310..33518364, complement)
106 current UNSW_CanFamBas_1.0 (GCF_013276365.1) 3 NC_049744.1 (33083854..33780951, complement)

Chromosome 3 - NC_051807.1Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC119871300 Neighboring gene uncharacterized LOC119876131 Neighboring gene uncharacterized LOC111095354 Neighboring gene 60S ribosomal protein L37a-like Neighboring gene TATA box-binding protein-associated factor RNA polymerase I subunit D-like Neighboring gene uncharacterized LOC111095179 Neighboring gene uncharacterized LOC119871184 Neighboring gene U6 spliceosomal RNA Neighboring gene gamma-aminobutyric acid type A receptor subunit alpha5

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

General gene information

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Markers

Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables GABA-A receptor activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables GABA-gated chloride ion channel activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables benzodiazepine receptor activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables inhibitory extracellular ligand-gated monoatomic ion channel activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables transmitter-gated monoatomic ion channel activity involved in regulation of postsynaptic membrane potential IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in chloride transport IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in gamma-aminobutyric acid signaling pathway IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in monoatomic ion transmembrane transport IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in nervous system process IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in regulation of postsynaptic membrane potential IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in signal transduction IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in synaptic transmission, GABAergic IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
part_of GABA-A receptor complex IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in dendrite membrane IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in neuron projection IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in postsynapse IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in synapse IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
gamma-aminobutyric acid receptor subunit gamma-3
Names
gamma-aminobutyric acid type A receptor gamma3 subunit

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Canis lupus familiaris Annotation Release 106 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference ROS_Cfam_1.0

Genomic

  1. NC_051807.1 Reference ROS_Cfam_1.0

    Range
    33293570..33977676 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038661082.1 → XP_038517010.1  gamma-aminobutyric acid receptor subunit gamma-3 isoform X1

    UniProtKB/TrEMBL
    A0A8C0Q305, A0A8I3P8N4
    Related
    ENSCAFP00845024432.1, ENSCAFT00845031211.1
    Conserved Domains (2) summary
    TIGR00860
    Location:50 → 464
    LIC; Cation transporter family protein
    cd19000
    Location:71 → 252
    LGIC_ECD_GABAAR_G; extracellular domain of gamma-aminobutyric acid receptor subunit gamma

  2. XM_038661083.1 → XP_038517011.1  gamma-aminobutyric acid receptor subunit gamma-3 isoform X2

    Conserved Domains (3) summary
    TIGR00860
    Location:4 → 352
    LIC; Cation transporter family protein
    cd03558
    Location:59 → 73
    LGIC_ECD; Cys-loop [structural motif]
    cl28912
    Location:1 → 140
    LGIC_ECD; extracellular domain (ECD) of Cys-loop neurotransmitter-gated ion channels (also known as ligand-gated ion channel (LGIC))

  3. XM_038661084.1 → XP_038517012.1  gamma-aminobutyric acid receptor subunit gamma-3 isoform X3

    Conserved Domains (2) summary
    cd03558
    Location:171 → 185
    LGIC_ECD; Cys-loop [structural motif]
    cl28912
    Location:71 → 241
    LGIC_ECD; extracellular domain (ECD) of Cys-loop neurotransmitter-gated ion channels (also known as ligand-gated ion channel (LGIC))

Alternate UMICH_Zoey_3.1

Genomic

  1. NC_049263.1 Alternate UMICH_Zoey_3.1

    Range
    32834310..33518364 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038471645.1 → XP_038327573.1  gamma-aminobutyric acid receptor subunit gamma-3 isoform X1

    Conserved Domains (2) summary
    TIGR00860
    Location:50 → 464
    LIC; Cation transporter family protein
    cd19000
    Location:71 → 252
    LGIC_ECD_GABAAR_G; extracellular domain of gamma-aminobutyric acid receptor subunit gamma

  2. XM_038471646.1 → XP_038327574.1  gamma-aminobutyric acid receptor subunit gamma-3 isoform X2

    Conserved Domains (3) summary
    TIGR00860
    Location:4 → 352
    LIC; Cation transporter family protein
    cd03558
    Location:59 → 73
    LGIC_ECD; Cys-loop [structural motif]
    cl28912
    Location:1 → 140
    LGIC_ECD; extracellular domain (ECD) of Cys-loop neurotransmitter-gated ion channels (also known as ligand-gated ion channel (LGIC))

  3. XM_038471647.1 → XP_038327575.1  gamma-aminobutyric acid receptor subunit gamma-3 isoform X3

    Conserved Domains (2) summary
    cd03558
    Location:171 → 185
    LGIC_ECD; Cys-loop [structural motif]
    cl28912
    Location:71 → 241
    LGIC_ECD; extracellular domain (ECD) of Cys-loop neurotransmitter-gated ion channels (also known as ligand-gated ion channel (LGIC))

Alternate UNSW_CanFamBas_1.0

Genomic

  1. NC_049744.1 Alternate UNSW_CanFamBas_1.0

    Range
    33083854..33780951 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038596872.1 → XP_038452800.1  gamma-aminobutyric acid receptor subunit gamma-3 isoform X1

    Conserved Domains (2) summary
    TIGR00860
    Location:50 → 464
    LIC; Cation transporter family protein
    cd19000
    Location:71 → 252
    LGIC_ECD_GABAAR_G; extracellular domain of gamma-aminobutyric acid receptor subunit gamma

  2. XM_038596873.1 → XP_038452801.1  gamma-aminobutyric acid receptor subunit gamma-3 isoform X2

    Conserved Domains (3) summary
    TIGR00860
    Location:4 → 352
    LIC; Cation transporter family protein
    cd03558
    Location:59 → 73
    LGIC_ECD; Cys-loop [structural motif]
    cl28912
    Location:1 → 140
    LGIC_ECD; extracellular domain (ECD) of Cys-loop neurotransmitter-gated ion channels (also known as ligand-gated ion channel (LGIC))

  3. XM_038596874.1 → XP_038452802.1  gamma-aminobutyric acid receptor subunit gamma-3 isoform X3

    Conserved Domains (2) summary
    cd03558
    Location:171 → 185
    LGIC_ECD; Cys-loop [structural motif]
    cl28912
    Location:71 → 241
    LGIC_ECD; extracellular domain (ECD) of Cys-loop neurotransmitter-gated ion channels (also known as ligand-gated ion channel (LGIC))

Alternate UU_Cfam_GSD_1.0

Genomic

  1. NC_049224.1 Alternate UU_Cfam_GSD_1.0

    Range
    33186801..33927787 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038532572.1 → XP_038388500.1  gamma-aminobutyric acid receptor subunit gamma-3 isoform X4

    UniProtKB/TrEMBL
    A0A8C0Q305, A0A8I3P8N4
    Conserved Domains (2) summary
    TIGR00860
    Location:50 → 464
    LIC; Cation transporter family protein
    cd19000
    Location:71 → 252
    LGIC_ECD_GABAAR_G; extracellular domain of gamma-aminobutyric acid receptor subunit gamma

Alternate Dog10K_Boxer_Tasha Primary Assembly

Genomic

  1. NC_006585.4 Alternate Dog10K_Boxer_Tasha Primary Assembly

    Range
    35646875..36332262 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_545802.6 → XP_545802.3  gamma-aminobutyric acid receptor subunit gamma-3 isoform X1

    UniProtKB/TrEMBL
    A0A8C0Q305, A0A8I3P8N4
    Conserved Domains (2) summary
    TIGR00860
    Location:50 → 464
    LIC; Cation transporter family protein
    cd19000
    Location:71 → 252
    LGIC_ECD_GABAAR_G; extracellular domain of gamma-aminobutyric acid receptor subunit gamma

  2. XM_038472689.1 → XP_038328617.1  gamma-aminobutyric acid receptor subunit gamma-3 isoform X2

    Conserved Domains (3) summary
    TIGR00860
    Location:4 → 352
    LIC; Cation transporter family protein
    cd03558
    Location:59 → 73
    LGIC_ECD; Cys-loop [structural motif]
    cl28912
    Location:1 → 140
    LGIC_ECD; extracellular domain (ECD) of Cys-loop neurotransmitter-gated ion channels (also known as ligand-gated ion channel (LGIC))

  3. XM_014112291.3 → XP_013967766.1  gamma-aminobutyric acid receptor subunit gamma-3 isoform X3

    Conserved Domains (2) summary
    cd03558
    Location:171 → 185
    LGIC_ECD; Cys-loop [structural motif]
    cl28912
    Location:71 → 241
    LGIC_ECD; extracellular domain (ECD) of Cys-loop neurotransmitter-gated ion channels (also known as ligand-gated ion channel (LGIC))
Nucleotide Protein
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