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SPPL3 signal peptide peptidase like 3 [ Canis lupus familiaris (dog) ]

Gene ID: 486301, updated on 9-Mar-2024

Summary

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Official Symbol
SPPL3provided by VGNC
Official Full Name
signal peptide peptidase like 3provided by VGNC
Primary source
VGNC:VGNC:46761
See related
Ensembl:ENSCAFG00845030094
Gene type
protein coding
RefSeq status
MODEL
Organism
Canis lupus familiaris (sub-species: familiaris)
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Carnivora; Caniformia; Canidae; Canis
Orthologs
human mouse all
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Genomic context

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Location:
chromosome: 26
Exon count:
14
Annotation release Status Assembly Chr Location
106 current ROS_Cfam_1.0 (GCF_014441545.1) 26 NC_051830.1 (16886222..17026542, complement)
106 current Dog10K_Boxer_Tasha (GCF_000002285.5) 26 NC_006608.4 (16622725..16762963, complement)
106 current UU_Cfam_GSD_1.0 (GCF_011100685.1) 26 NC_049247.1 (16965017..17105003, complement)
106 current UMICH_Zoey_3.1 (GCF_005444595.1) 26 NC_049286.1 (16847005..16987200, complement)
106 current UNSW_CanFamBas_1.0 (GCF_013276365.1) 26 NC_049767.1 (16922683..17062392, complement)

Chromosome 26 - NC_051830.1Genomic Context describing neighboring genes Neighboring gene unc-119 lipid binding chaperone B Neighboring gene acyl-CoA dehydrogenase short chain Neighboring gene thymosin beta-4-like Neighboring gene transfer RNA lysine (anticodon CUU) Neighboring gene ribosomal protein, large, P0 pseudogene Neighboring gene uncharacterized LOC102152191 Neighboring gene HNF1 homeobox A

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables aspartic endopeptidase activity, intramembrane cleaving IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in membrane protein proteolysis IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in signal peptide processing IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in Golgi-associated vesicle membrane IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in cytoplasmic side of endoplasmic reticulum membrane IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in lumenal side of endoplasmic reticulum membrane IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
signal peptide peptidase-like 3
XP_022266508.1
XP_022266509.1
XP_038292872.1
XP_038292873.1
XP_038292874.1
XP_038292875.1
XP_038314834.1
XP_038367767.1
XP_038367768.1
XP_038367769.1
XP_038367770.1
XP_038431263.1
XP_038431264.1
XP_038431265.1
XP_038431266.1
XP_038495450.1
XP_038495451.1
XP_038495452.1
XP_038495453.1
XP_543427.2

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Canis lupus familiaris Annotation Release 106 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference ROS_Cfam_1.0

Genomic

  1. NC_051830.1 Reference ROS_Cfam_1.0

    Range
    16886222..17026542 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038436944.1 → XP_038292872.1  signal peptide peptidase-like 3 isoform X1

    UniProtKB/TrEMBL
    A0A8C0R4V9, A0A8C0TCU3, A0A8I3Q311
    Related
    ENSCAFP00845041892.1, ENSCAFT00845053334.1
    Conserved Domains (1) summary
    pfam04258
    Location:61 → 374
    Peptidase_A22B; Signal peptide peptidase

  2. XM_038436946.1 → XP_038292874.1  signal peptide peptidase-like 3 isoform X3

    UniProtKB/TrEMBL
    A0A8C0TFH9
    Conserved Domains (1) summary
    pfam04258
    Location:24 → 337
    Peptidase_A22B; Signal peptide peptidase

  3. XM_038436945.1 → XP_038292873.1  signal peptide peptidase-like 3 isoform X2

    Conserved Domains (1) summary
    pfam04258
    Location:39 → 352
    Peptidase_A22B; Signal peptide peptidase

  4. XM_038436947.1 → XP_038292875.1  signal peptide peptidase-like 3 isoform X4

    Conserved Domains (1) summary
    pfam04258
    Location:7 → 318
    Peptidase_A22B; Signal peptide peptidase

Alternate UMICH_Zoey_3.1

Genomic

  1. NC_049286.1 Alternate UMICH_Zoey_3.1

    Range
    16847005..16987200 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038511839.1 → XP_038367767.1  signal peptide peptidase-like 3 isoform X1

    Conserved Domains (1) summary
    pfam04258
    Location:61 → 374
    Peptidase_A22B; Signal peptide peptidase

  2. XM_038511841.1 → XP_038367769.1  signal peptide peptidase-like 3 isoform X3

    Conserved Domains (1) summary
    pfam04258
    Location:24 → 337
    Peptidase_A22B; Signal peptide peptidase

  3. XM_038511840.1 → XP_038367768.1  signal peptide peptidase-like 3 isoform X2

    Conserved Domains (1) summary
    pfam04258
    Location:39 → 352
    Peptidase_A22B; Signal peptide peptidase

  4. XM_038511842.1 → XP_038367770.1  signal peptide peptidase-like 3 isoform X4

    Conserved Domains (1) summary
    pfam04258
    Location:7 → 318
    Peptidase_A22B; Signal peptide peptidase

Alternate UNSW_CanFamBas_1.0

Genomic

  1. NC_049767.1 Alternate UNSW_CanFamBas_1.0

    Range
    16922683..17062392 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038639522.1 → XP_038495450.1  signal peptide peptidase-like 3 isoform X1

    Conserved Domains (1) summary
    pfam04258
    Location:61 → 374
    Peptidase_A22B; Signal peptide peptidase

  2. XM_038639524.1 → XP_038495452.1  signal peptide peptidase-like 3 isoform X3

    Conserved Domains (1) summary
    pfam04258
    Location:24 → 337
    Peptidase_A22B; Signal peptide peptidase

  3. XM_038639523.1 → XP_038495451.1  signal peptide peptidase-like 3 isoform X2

    Conserved Domains (1) summary
    pfam04258
    Location:39 → 352
    Peptidase_A22B; Signal peptide peptidase

  4. XM_038639525.1 → XP_038495453.1  signal peptide peptidase-like 3 isoform X4

    Conserved Domains (1) summary
    pfam04258
    Location:7 → 318
    Peptidase_A22B; Signal peptide peptidase

Alternate UU_Cfam_GSD_1.0

Genomic

  1. NC_049247.1 Alternate UU_Cfam_GSD_1.0

    Range
    16965017..17105003 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038575335.1 → XP_038431263.1  signal peptide peptidase-like 3 isoform X1

    UniProtKB/TrEMBL
    A0A8C0R4V9, A0A8C0TCU3, A0A8I3Q311
    Conserved Domains (1) summary
    pfam04258
    Location:61 → 374
    Peptidase_A22B; Signal peptide peptidase

  2. XM_038575337.1 → XP_038431265.1  signal peptide peptidase-like 3 isoform X3

    UniProtKB/TrEMBL
    A0A8C0TFH9
    Conserved Domains (1) summary
    pfam04258
    Location:24 → 337
    Peptidase_A22B; Signal peptide peptidase

  3. XM_038575336.1 → XP_038431264.1  signal peptide peptidase-like 3 isoform X2

    Conserved Domains (1) summary
    pfam04258
    Location:39 → 352
    Peptidase_A22B; Signal peptide peptidase

  4. XM_038575338.1 → XP_038431266.1  signal peptide peptidase-like 3 isoform X4

    Conserved Domains (1) summary
    pfam04258
    Location:7 → 318
    Peptidase_A22B; Signal peptide peptidase

Alternate Dog10K_Boxer_Tasha Primary Assembly

Genomic

  1. NC_006608.4 Alternate Dog10K_Boxer_Tasha Primary Assembly

    Range
    16622725..16762963 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_543427.7 → XP_543427.2  signal peptide peptidase-like 3 isoform X1

    See identical proteins and their annotated locations for XP_543427.2

    UniProtKB/TrEMBL
    A0A8C0R4V9, A0A8C0TCU3, A0A8I3Q311
    Conserved Domains (1) summary
    pfam04258
    Location:61 → 374
    Peptidase_A22B; Signal peptide peptidase

  2. XM_022410801.2 → XP_022266509.1  signal peptide peptidase-like 3 isoform X3

    UniProtKB/TrEMBL
    A0A8C0TFH9
    Conserved Domains (1) summary
    pfam04258
    Location:24 → 337
    Peptidase_A22B; Signal peptide peptidase

  3. XM_022410800.2 → XP_022266508.1  signal peptide peptidase-like 3 isoform X2

    Conserved Domains (1) summary
    pfam04258
    Location:39 → 352
    Peptidase_A22B; Signal peptide peptidase

  4. XM_038458906.1 → XP_038314834.1  signal peptide peptidase-like 3 isoform X4

    Conserved Domains (1) summary
    pfam04258
    Location:7 → 318
    Peptidase_A22B; Signal peptide peptidase
Nucleotide Protein
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