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TSEN2 tRNA splicing endonuclease subunit 2 [ Canis lupus familiaris (dog) ]

Gene ID: 484651, updated on 5-Mar-2024

Summary

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Gene symbol
TSEN2
Gene description
tRNA splicing endonuclease subunit 2
See related
Ensembl:ENSCAFG00845028923
Gene type
protein coding
RefSeq status
MODEL
Organism
Canis lupus familiaris (sub-species: familiaris)
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Carnivora; Caniformia; Canidae; Canis
Orthologs
human mouse all
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Genomic context

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Location:
chromosome: 20
Exon count:
17
Annotation release Status Assembly Chr Location
106 current ROS_Cfam_1.0 (GCF_014441545.1) 20 NC_051824.1 (6060280..6119929, complement)
106 current Dog10K_Boxer_Tasha (GCF_000002285.5) 20 NC_006602.4 (6067927..6127172, complement)
106 current UU_Cfam_GSD_1.0 (GCF_011100685.1) 20 NC_049241.1 (6106273..6164648, complement)
106 current UMICH_Zoey_3.1 (GCF_005444595.1) 20 NC_049280.1 (5775670..5835307, complement)
106 current UNSW_CanFamBas_1.0 (GCF_013276365.1) 20 NC_049761.1 (6129564..6189194, complement)

Chromosome 20 - NC_051824.1Genomic Context describing neighboring genes Neighboring gene thymosin beta-4-like Neighboring gene replication protein A 32 kDa subunit-like Neighboring gene MKRN2 opposite strand Neighboring gene peroxisome proliferator activated receptor gamma Neighboring gene uncharacterized LOC111091237 Neighboring gene uncharacterized LOC119864630

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables nucleic acid binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables tRNA-intron endonuclease activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in tRNA splicing, via endonucleolytic cleavage and ligation IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in tRNA-type intron splice site recognition and cleavage IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
part_of tRNA-intron endonuclease complex IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
tRNA-splicing endonuclease subunit Sen2
Names
tRNA splicing endonuclease 2 homolog
XP_013977123.1
XP_013977124.1
XP_013977126.1
XP_038282828.1
XP_038282829.1
XP_038282830.1
XP_038358624.1
XP_038358625.1
XP_038358626.1
XP_038421542.1
XP_038421543.1
XP_038421544.1
XP_038485675.1
XP_038485676.1
XP_038485677.1

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Canis lupus familiaris Annotation Release 106 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference ROS_Cfam_1.0

Genomic

  1. NC_051824.1 Reference ROS_Cfam_1.0

    Range
    6060280..6119929 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038426901.1 → XP_038282829.1  tRNA-splicing endonuclease subunit Sen2

    UniProtKB/TrEMBL
    A0A8C0K243, A0A8C0TFY8, A0A8C0TKA6, A0A8I3Q1M8, A0A8P0N7R3
    Conserved Domains (2) summary
    COG1676
    Location:246 → 430
    SEN2; tRNA splicing endonuclease [Translation, ribosomal structure and biogenesis]
    cd22363
    Location:344 → 435
    tRNA-intron_lyase_C; catalytic C-terminal domain of the tRNA-intron lyase

  2. XM_038426900.1 → XP_038282828.1  tRNA-splicing endonuclease subunit Sen2

    UniProtKB/TrEMBL
    A0A8C0K243, A0A8C0TFY8, A0A8C0TKA6, A0A8I3Q1M8, A0A8P0N7R3
    Conserved Domains (2) summary
    COG1676
    Location:246 → 430
    SEN2; tRNA splicing endonuclease [Translation, ribosomal structure and biogenesis]
    cd22363
    Location:344 → 435
    tRNA-intron_lyase_C; catalytic C-terminal domain of the tRNA-intron lyase

  3. XM_038426902.1 → XP_038282830.1  tRNA-splicing endonuclease subunit Sen2

    UniProtKB/TrEMBL
    A0A8C0K243, A0A8C0TFY8, A0A8C0TKA6, A0A8I3Q1M8, A0A8P0N7R3
    Related
    ENSCAFP00845040129.1, ENSCAFT00845051171.1
    Conserved Domains (2) summary
    COG1676
    Location:246 → 430
    SEN2; tRNA splicing endonuclease [Translation, ribosomal structure and biogenesis]
    cd22363
    Location:344 → 435
    tRNA-intron_lyase_C; catalytic C-terminal domain of the tRNA-intron lyase

RNA

  1. XR_005297583.1 RNA Sequence

  2. XR_005297584.1 RNA Sequence

  3. XR_005297585.1 RNA Sequence

Alternate UMICH_Zoey_3.1

Genomic

  1. NC_049280.1 Alternate UMICH_Zoey_3.1

    Range
    5775670..5835307 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038502697.1 → XP_038358625.1  tRNA-splicing endonuclease subunit Sen2

    Conserved Domains (2) summary
    COG1676
    Location:246 → 430
    SEN2; tRNA splicing endonuclease [Translation, ribosomal structure and biogenesis]
    cd22363
    Location:344 → 435
    tRNA-intron_lyase_C; catalytic C-terminal domain of the tRNA-intron lyase

  2. XM_038502696.1 → XP_038358624.1  tRNA-splicing endonuclease subunit Sen2

    Conserved Domains (2) summary
    COG1676
    Location:246 → 430
    SEN2; tRNA splicing endonuclease [Translation, ribosomal structure and biogenesis]
    cd22363
    Location:344 → 435
    tRNA-intron_lyase_C; catalytic C-terminal domain of the tRNA-intron lyase

  3. XM_038502698.1 → XP_038358626.1  tRNA-splicing endonuclease subunit Sen2

    Conserved Domains (2) summary
    COG1676
    Location:246 → 430
    SEN2; tRNA splicing endonuclease [Translation, ribosomal structure and biogenesis]
    cd22363
    Location:344 → 435
    tRNA-intron_lyase_C; catalytic C-terminal domain of the tRNA-intron lyase

RNA

  1. XR_005340799.1 RNA Sequence

  2. XR_005340800.1 RNA Sequence

  3. XR_005340801.1 RNA Sequence

Alternate UNSW_CanFamBas_1.0

Genomic

  1. NC_049761.1 Alternate UNSW_CanFamBas_1.0

    Range
    6129564..6189194 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038629748.1 → XP_038485676.1  tRNA-splicing endonuclease subunit Sen2

    Conserved Domains (2) summary
    COG1676
    Location:246 → 430
    SEN2; tRNA splicing endonuclease [Translation, ribosomal structure and biogenesis]
    cd22363
    Location:344 → 435
    tRNA-intron_lyase_C; catalytic C-terminal domain of the tRNA-intron lyase

  2. XM_038629747.1 → XP_038485675.1  tRNA-splicing endonuclease subunit Sen2

    Conserved Domains (2) summary
    COG1676
    Location:246 → 430
    SEN2; tRNA splicing endonuclease [Translation, ribosomal structure and biogenesis]
    cd22363
    Location:344 → 435
    tRNA-intron_lyase_C; catalytic C-terminal domain of the tRNA-intron lyase

  3. XM_038629749.1 → XP_038485677.1  tRNA-splicing endonuclease subunit Sen2

    Conserved Domains (2) summary
    COG1676
    Location:246 → 430
    SEN2; tRNA splicing endonuclease [Translation, ribosomal structure and biogenesis]
    cd22363
    Location:344 → 435
    tRNA-intron_lyase_C; catalytic C-terminal domain of the tRNA-intron lyase

RNA

  1. XR_005408564.1 RNA Sequence

  2. XR_005408565.1 RNA Sequence

  3. XR_005408566.1 RNA Sequence

Alternate UU_Cfam_GSD_1.0

Genomic

  1. NC_049241.1 Alternate UU_Cfam_GSD_1.0

    Range
    6106273..6164648 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038565615.1 → XP_038421543.1  tRNA-splicing endonuclease subunit Sen2

    UniProtKB/TrEMBL
    A0A8C0PDE7, A0A8C0TKA6, A0A8P0N7R3

  2. XM_038565614.1 → XP_038421542.1  tRNA-splicing endonuclease subunit Sen2

    UniProtKB/TrEMBL
    A0A8C0PDE7, A0A8C0TKA6, A0A8P0N7R3

  3. XM_038565616.1 → XP_038421544.1  tRNA-splicing endonuclease subunit Sen2

    UniProtKB/TrEMBL
    A0A8C0PDE7, A0A8C0TKA6, A0A8P0N7R3

RNA

  1. XR_005374566.1 RNA Sequence

  2. XR_005374567.1 RNA Sequence

  3. XR_005374568.1 RNA Sequence

Alternate Dog10K_Boxer_Tasha Primary Assembly

Genomic

  1. NC_006602.4 Alternate Dog10K_Boxer_Tasha Primary Assembly

    Range
    6067927..6127172 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_014121648.3 → XP_013977123.1  tRNA-splicing endonuclease subunit Sen2

    UniProtKB/TrEMBL
    A0A8C0K243, A0A8C0TFY8, A0A8C0TKA6, A0A8I3Q1M8, A0A8P0N7R3
    Conserved Domains (2) summary
    COG1676
    Location:246 → 430
    SEN2; tRNA splicing endonuclease [Translation, ribosomal structure and biogenesis]
    cd22363
    Location:344 → 435
    tRNA-intron_lyase_C; catalytic C-terminal domain of the tRNA-intron lyase

  2. XM_014121649.3 → XP_013977124.1  tRNA-splicing endonuclease subunit Sen2

    UniProtKB/TrEMBL
    A0A8C0K243, A0A8C0TFY8, A0A8C0TKA6, A0A8I3Q1M8, A0A8P0N7R3
    Conserved Domains (2) summary
    COG1676
    Location:246 → 430
    SEN2; tRNA splicing endonuclease [Translation, ribosomal structure and biogenesis]
    cd22363
    Location:344 → 435
    tRNA-intron_lyase_C; catalytic C-terminal domain of the tRNA-intron lyase

  3. XM_014121651.3 → XP_013977126.1  tRNA-splicing endonuclease subunit Sen2

    UniProtKB/TrEMBL
    A0A8C0K243, A0A8C0TFY8, A0A8C0TKA6, A0A8I3Q1M8, A0A8P0N7R3
    Conserved Domains (2) summary
    COG1676
    Location:246 → 430
    SEN2; tRNA splicing endonuclease [Translation, ribosomal structure and biogenesis]
    cd22363
    Location:344 → 435
    tRNA-intron_lyase_C; catalytic C-terminal domain of the tRNA-intron lyase

RNA

  1. XR_005312466.1 RNA Sequence

  2. XR_005312467.1 RNA Sequence

  3. XR_005312468.1 RNA Sequence

Nucleotide Protein
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