U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

TLR3 toll like receptor 3 [ Canis lupus familiaris (dog) ]

Gene ID: 482905, updated on 5-Mar-2024

Summary

Go to the top of the page Help
Official Symbol
TLR3provided by VGNC
Official Full Name
toll like receptor 3provided by VGNC
Primary source
VGNC:VGNC:51831
See related
Ensembl:ENSCAFG00845019801
Gene type
protein coding
RefSeq status
MODEL
Organism
Canis lupus familiaris (sub-species: familiaris)
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Carnivora; Caniformia; Canidae; Canis
Orthologs
human mouse all
NEW
Try the new Gene table
Try the new Transcript table

Genomic context

Go to the top of the page Help
Location:
chromosome: 16
Exon count:
9
Annotation release Status Assembly Chr Location
106 current ROS_Cfam_1.0 (GCF_014441545.1) 16 NC_051820.1 (46830974..46859705, complement)
106 current Dog10K_Boxer_Tasha (GCF_000002285.5) 16 NC_006598.4 (45103720..45132454, complement)
106 current UU_Cfam_GSD_1.0 (GCF_011100685.1) 16 NC_049237.1 (45543452..45571950, complement)
106 current UMICH_Zoey_3.1 (GCF_005444595.1) 16 NC_049276.1 (44798956..44827679, complement)
106 current UNSW_CanFamBas_1.0 (GCF_013276365.1) 16 NC_049757.1 (45411963..45440690, complement)

Chromosome 16 - NC_051820.1Genomic Context describing neighboring genes Neighboring gene cytochrome P450 family 4 subfamily V member 2 Neighboring gene family with sequence similarity 149 member A Neighboring gene uncharacterized LOC111090181 Neighboring gene uncharacterized LOC111090337

Genomic regions, transcripts, and products

Go to the top of the page Help

Go to nucleotide: Graphics FASTA GenBank

Bibliography

Go to the top of the pageHelp

Related articles in PubMed

  1. Toll-like receptor 3 (TLR3): a new marker of canine monocytes-derived dendritic cells (cMo-DC). Bonnefont-Rebeix C, et al. Vet Immunol Immunopathol, 2007 Jul 15. PMID 17521746
  2. Toll- and NOD-like receptor mRNA expression in canine sino-nasal aspergillosis and idiopathic lymphoplasmacytic rhinitis. Mercier E, et al. Vet Immunol Immunopathol, 2012 Feb 15. PMID 22321737

GeneRIFs: Gene References Into Functions

General gene information

Go to the top of the page Help

Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables protein binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables transmembrane signaling receptor activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in immune response IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in inflammatory response IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in toll-like receptor signaling pathway IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in membrane IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

Go to the top of the page Help
Preferred Names
toll-like receptor 3

NCBI Reference Sequences (RefSeq)

Go to the top of the page Help

NEW Try the new Transcript table

RefSeqs of Annotated Genomes: Canis lupus familiaris Annotation Release 106 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference ROS_Cfam_1.0

Genomic

  1. NC_051820.1 Reference ROS_Cfam_1.0

    Range
    46830974..46859705 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038690137.1 → XP_038546065.1  toll-like receptor 3

    UniProtKB/TrEMBL
    A0A6S4HXZ1, A0A8C0S614, A0A8I3P6K4, A0A8P0SCN6
    Conserved Domains (6) summary
    TIGR00864
    Location:617 → 690
    PCC; polycystin cation channel protein
    smart00255
    Location:756 → 901
    TIR; Toll - interleukin 1 - resistance
    PLN00113
    Location:73 → 646
    PLN00113; leucine-rich repeat receptor-like protein kinase; Provisional
    sd00031
    Location:533 → 556
    LRR_1; leucine-rich repeat [structural motif]
    sd00033
    Location:34 → 53
    LRR_RI; leucine-rich repeat [structural motif]
    pfam17968
    Location:699 → 731
    Tlr3_TMD; Toll-like receptor 3 trans-membrane domain

  2. XM_038690140.1 → XP_038546068.1  toll-like receptor 3

    UniProtKB/TrEMBL
    A0A6S4HXZ1, A0A8C0S614, A0A8I3P6K4, A0A8P0SCN6
    Conserved Domains (6) summary
    TIGR00864
    Location:617 → 690
    PCC; polycystin cation channel protein
    smart00255
    Location:756 → 901
    TIR; Toll - interleukin 1 - resistance
    PLN00113
    Location:73 → 646
    PLN00113; leucine-rich repeat receptor-like protein kinase; Provisional
    sd00031
    Location:533 → 556
    LRR_1; leucine-rich repeat [structural motif]
    sd00033
    Location:34 → 53
    LRR_RI; leucine-rich repeat [structural motif]
    pfam17968
    Location:699 → 731
    Tlr3_TMD; Toll-like receptor 3 trans-membrane domain

  3. XM_038690139.1 → XP_038546067.1  toll-like receptor 3

    UniProtKB/TrEMBL
    A0A6S4HXZ1, A0A8C0S614, A0A8I3P6K4, A0A8P0SCN6
    Related
    ENSCAFP00845027329.1, ENSCAFT00845034893.1
    Conserved Domains (6) summary
    TIGR00864
    Location:617 → 690
    PCC; polycystin cation channel protein
    smart00255
    Location:756 → 901
    TIR; Toll - interleukin 1 - resistance
    PLN00113
    Location:73 → 646
    PLN00113; leucine-rich repeat receptor-like protein kinase; Provisional
    sd00031
    Location:533 → 556
    LRR_1; leucine-rich repeat [structural motif]
    sd00033
    Location:34 → 53
    LRR_RI; leucine-rich repeat [structural motif]
    pfam17968
    Location:699 → 731
    Tlr3_TMD; Toll-like receptor 3 trans-membrane domain

  4. XM_038690138.1 → XP_038546066.1  toll-like receptor 3

    UniProtKB/TrEMBL
    A0A6S4HXZ1, A0A8C0S614, A0A8I3P6K4, A0A8P0SCN6
    Conserved Domains (6) summary
    TIGR00864
    Location:617 → 690
    PCC; polycystin cation channel protein
    smart00255
    Location:756 → 901
    TIR; Toll - interleukin 1 - resistance
    PLN00113
    Location:73 → 646
    PLN00113; leucine-rich repeat receptor-like protein kinase; Provisional
    sd00031
    Location:533 → 556
    LRR_1; leucine-rich repeat [structural motif]
    sd00033
    Location:34 → 53
    LRR_RI; leucine-rich repeat [structural motif]
    pfam17968
    Location:699 → 731
    Tlr3_TMD; Toll-like receptor 3 trans-membrane domain

Alternate UMICH_Zoey_3.1

Genomic

  1. NC_049276.1 Alternate UMICH_Zoey_3.1

    Range
    44798956..44827679 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038497857.1 → XP_038353785.1  toll-like receptor 3

    Conserved Domains (6) summary
    TIGR00864
    Location:617 → 690
    PCC; polycystin cation channel protein
    smart00255
    Location:756 → 901
    TIR; Toll - interleukin 1 - resistance
    PLN00113
    Location:73 → 646
    PLN00113; leucine-rich repeat receptor-like protein kinase; Provisional
    sd00031
    Location:533 → 556
    LRR_1; leucine-rich repeat [structural motif]
    sd00033
    Location:34 → 53
    LRR_RI; leucine-rich repeat [structural motif]
    pfam17968
    Location:699 → 731
    Tlr3_TMD; Toll-like receptor 3 trans-membrane domain

  2. XM_038497860.1 → XP_038353788.1  toll-like receptor 3

    Conserved Domains (6) summary
    TIGR00864
    Location:617 → 690
    PCC; polycystin cation channel protein
    smart00255
    Location:756 → 901
    TIR; Toll - interleukin 1 - resistance
    PLN00113
    Location:73 → 646
    PLN00113; leucine-rich repeat receptor-like protein kinase; Provisional
    sd00031
    Location:533 → 556
    LRR_1; leucine-rich repeat [structural motif]
    sd00033
    Location:34 → 53
    LRR_RI; leucine-rich repeat [structural motif]
    pfam17968
    Location:699 → 731
    Tlr3_TMD; Toll-like receptor 3 trans-membrane domain

  3. XM_038497859.1 → XP_038353787.1  toll-like receptor 3

    Conserved Domains (6) summary
    TIGR00864
    Location:617 → 690
    PCC; polycystin cation channel protein
    smart00255
    Location:756 → 901
    TIR; Toll - interleukin 1 - resistance
    PLN00113
    Location:73 → 646
    PLN00113; leucine-rich repeat receptor-like protein kinase; Provisional
    sd00031
    Location:533 → 556
    LRR_1; leucine-rich repeat [structural motif]
    sd00033
    Location:34 → 53
    LRR_RI; leucine-rich repeat [structural motif]
    pfam17968
    Location:699 → 731
    Tlr3_TMD; Toll-like receptor 3 trans-membrane domain

  4. XM_038497858.1 → XP_038353786.1  toll-like receptor 3

    Conserved Domains (6) summary
    TIGR00864
    Location:617 → 690
    PCC; polycystin cation channel protein
    smart00255
    Location:756 → 901
    TIR; Toll - interleukin 1 - resistance
    PLN00113
    Location:73 → 646
    PLN00113; leucine-rich repeat receptor-like protein kinase; Provisional
    sd00031
    Location:533 → 556
    LRR_1; leucine-rich repeat [structural motif]
    sd00033
    Location:34 → 53
    LRR_RI; leucine-rich repeat [structural motif]
    pfam17968
    Location:699 → 731
    Tlr3_TMD; Toll-like receptor 3 trans-membrane domain

Alternate UNSW_CanFamBas_1.0

Genomic

  1. NC_049757.1 Alternate UNSW_CanFamBas_1.0

    Range
    45411963..45440690 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038624379.1 → XP_038480307.1  toll-like receptor 3

    Conserved Domains (6) summary
    TIGR00864
    Location:617 → 690
    PCC; polycystin cation channel protein
    smart00255
    Location:756 → 901
    TIR; Toll - interleukin 1 - resistance
    PLN00113
    Location:73 → 646
    PLN00113; leucine-rich repeat receptor-like protein kinase; Provisional
    sd00031
    Location:533 → 556
    LRR_1; leucine-rich repeat [structural motif]
    sd00033
    Location:34 → 53
    LRR_RI; leucine-rich repeat [structural motif]
    pfam17968
    Location:699 → 731
    Tlr3_TMD; Toll-like receptor 3 trans-membrane domain

  2. XM_038624382.1 → XP_038480310.1  toll-like receptor 3

    Conserved Domains (6) summary
    TIGR00864
    Location:617 → 690
    PCC; polycystin cation channel protein
    smart00255
    Location:756 → 901
    TIR; Toll - interleukin 1 - resistance
    PLN00113
    Location:73 → 646
    PLN00113; leucine-rich repeat receptor-like protein kinase; Provisional
    sd00031
    Location:533 → 556
    LRR_1; leucine-rich repeat [structural motif]
    sd00033
    Location:34 → 53
    LRR_RI; leucine-rich repeat [structural motif]
    pfam17968
    Location:699 → 731
    Tlr3_TMD; Toll-like receptor 3 trans-membrane domain

  3. XM_038624380.1 → XP_038480308.1  toll-like receptor 3

    Conserved Domains (6) summary
    TIGR00864
    Location:617 → 690
    PCC; polycystin cation channel protein
    smart00255
    Location:756 → 901
    TIR; Toll - interleukin 1 - resistance
    PLN00113
    Location:73 → 646
    PLN00113; leucine-rich repeat receptor-like protein kinase; Provisional
    sd00031
    Location:533 → 556
    LRR_1; leucine-rich repeat [structural motif]
    sd00033
    Location:34 → 53
    LRR_RI; leucine-rich repeat [structural motif]
    pfam17968
    Location:699 → 731
    Tlr3_TMD; Toll-like receptor 3 trans-membrane domain

  4. XM_038624381.1 → XP_038480309.1  toll-like receptor 3

    Conserved Domains (6) summary
    TIGR00864
    Location:617 → 690
    PCC; polycystin cation channel protein
    smart00255
    Location:756 → 901
    TIR; Toll - interleukin 1 - resistance
    PLN00113
    Location:73 → 646
    PLN00113; leucine-rich repeat receptor-like protein kinase; Provisional
    sd00031
    Location:533 → 556
    LRR_1; leucine-rich repeat [structural motif]
    sd00033
    Location:34 → 53
    LRR_RI; leucine-rich repeat [structural motif]
    pfam17968
    Location:699 → 731
    Tlr3_TMD; Toll-like receptor 3 trans-membrane domain

Alternate UU_Cfam_GSD_1.0

Genomic

  1. NC_049237.1 Alternate UU_Cfam_GSD_1.0

    Range
    45543452..45571950 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038560328.1 → XP_038416256.1  toll-like receptor 3

    UniProtKB/TrEMBL
    A0A8C0S614
    Conserved Domains (6) summary
    TIGR00864
    Location:617 → 690
    PCC; polycystin cation channel protein
    smart00255
    Location:756 → 901
    TIR; Toll - interleukin 1 - resistance
    PLN00113
    Location:73 → 646
    PLN00113; leucine-rich repeat receptor-like protein kinase; Provisional
    sd00031
    Location:533 → 556
    LRR_1; leucine-rich repeat [structural motif]
    sd00033
    Location:55 → 77
    LRR_RI; leucine-rich repeat [structural motif]
    pfam17968
    Location:699 → 731
    Tlr3_TMD; Toll-like receptor 3 trans-membrane domain

  2. XM_038560330.1 → XP_038416258.1  toll-like receptor 3

    UniProtKB/TrEMBL
    A0A8C0S614
    Conserved Domains (6) summary
    TIGR00864
    Location:617 → 690
    PCC; polycystin cation channel protein
    smart00255
    Location:756 → 901
    TIR; Toll - interleukin 1 - resistance
    PLN00113
    Location:73 → 646
    PLN00113; leucine-rich repeat receptor-like protein kinase; Provisional
    sd00031
    Location:533 → 556
    LRR_1; leucine-rich repeat [structural motif]
    sd00033
    Location:55 → 77
    LRR_RI; leucine-rich repeat [structural motif]
    pfam17968
    Location:699 → 731
    Tlr3_TMD; Toll-like receptor 3 trans-membrane domain

  3. XM_038560329.1 → XP_038416257.1  toll-like receptor 3

    UniProtKB/TrEMBL
    A0A8C0S614
    Conserved Domains (6) summary
    TIGR00864
    Location:617 → 690
    PCC; polycystin cation channel protein
    smart00255
    Location:756 → 901
    TIR; Toll - interleukin 1 - resistance
    PLN00113
    Location:73 → 646
    PLN00113; leucine-rich repeat receptor-like protein kinase; Provisional
    sd00031
    Location:533 → 556
    LRR_1; leucine-rich repeat [structural motif]
    sd00033
    Location:55 → 77
    LRR_RI; leucine-rich repeat [structural motif]
    pfam17968
    Location:699 → 731
    Tlr3_TMD; Toll-like receptor 3 trans-membrane domain

  4. XM_038560331.1 → XP_038416259.1  toll-like receptor 3

    UniProtKB/TrEMBL
    A0A8C0S614
    Conserved Domains (6) summary
    TIGR00864
    Location:617 → 690
    PCC; polycystin cation channel protein
    smart00255
    Location:756 → 901
    TIR; Toll - interleukin 1 - resistance
    PLN00113
    Location:73 → 646
    PLN00113; leucine-rich repeat receptor-like protein kinase; Provisional
    sd00031
    Location:533 → 556
    LRR_1; leucine-rich repeat [structural motif]
    sd00033
    Location:55 → 77
    LRR_RI; leucine-rich repeat [structural motif]
    pfam17968
    Location:699 → 731
    Tlr3_TMD; Toll-like receptor 3 trans-membrane domain

Alternate Dog10K_Boxer_Tasha Primary Assembly

Genomic

  1. NC_006598.4 Alternate Dog10K_Boxer_Tasha Primary Assembly

    Range
    45103720..45132454 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_022404183.2 → XP_022259891.1  toll-like receptor 3

    UniProtKB/TrEMBL
    A0A6S4HXZ1, A0A8C0S614, A0A8I3P6K4, A0A8P0SCN6
    Conserved Domains (6) summary
    TIGR00864
    Location:617 → 690
    PCC; polycystin cation channel protein
    smart00255
    Location:756 → 901
    TIR; Toll - interleukin 1 - resistance
    PLN00113
    Location:73 → 646
    PLN00113; leucine-rich repeat receptor-like protein kinase; Provisional
    sd00031
    Location:533 → 556
    LRR_1; leucine-rich repeat [structural motif]
    sd00033
    Location:34 → 53
    LRR_RI; leucine-rich repeat [structural motif]
    pfam17968
    Location:699 → 731
    Tlr3_TMD; Toll-like receptor 3 trans-membrane domain

  2. XM_038452669.1 → XP_038308597.1  toll-like receptor 3

    UniProtKB/TrEMBL
    A0A6S4HXZ1, A0A8C0S614, A0A8I3P6K4, A0A8P0SCN6
    Conserved Domains (6) summary
    TIGR00864
    Location:617 → 690
    PCC; polycystin cation channel protein
    smart00255
    Location:756 → 901
    TIR; Toll - interleukin 1 - resistance
    PLN00113
    Location:73 → 646
    PLN00113; leucine-rich repeat receptor-like protein kinase; Provisional
    sd00031
    Location:533 → 556
    LRR_1; leucine-rich repeat [structural motif]
    sd00033
    Location:34 → 53
    LRR_RI; leucine-rich repeat [structural motif]
    pfam17968
    Location:699 → 731
    Tlr3_TMD; Toll-like receptor 3 trans-membrane domain

  3. XM_005629968.4 → XP_005630025.1  toll-like receptor 3

    See identical proteins and their annotated locations for XP_005630025.1

    UniProtKB/TrEMBL
    A0A6S4HXZ1, A0A8C0S614, A0A8I3P6K4, A0A8P0SCN6
    Conserved Domains (6) summary
    TIGR00864
    Location:617 → 690
    PCC; polycystin cation channel protein
    smart00255
    Location:756 → 901
    TIR; Toll - interleukin 1 - resistance
    PLN00113
    Location:73 → 646
    PLN00113; leucine-rich repeat receptor-like protein kinase; Provisional
    sd00031
    Location:533 → 556
    LRR_1; leucine-rich repeat [structural motif]
    sd00033
    Location:34 → 53
    LRR_RI; leucine-rich repeat [structural motif]
    pfam17968
    Location:699 → 731
    Tlr3_TMD; Toll-like receptor 3 trans-membrane domain

  4. XM_038452668.1 → XP_038308596.1  toll-like receptor 3

    UniProtKB/TrEMBL
    A0A6S4HXZ1, A0A8C0S614, A0A8I3P6K4, A0A8P0SCN6
    Conserved Domains (6) summary
    TIGR00864
    Location:617 → 690
    PCC; polycystin cation channel protein
    smart00255
    Location:756 → 901
    TIR; Toll - interleukin 1 - resistance
    PLN00113
    Location:73 → 646
    PLN00113; leucine-rich repeat receptor-like protein kinase; Provisional
    sd00031
    Location:533 → 556
    LRR_1; leucine-rich repeat [structural motif]
    sd00033
    Location:34 → 53
    LRR_RI; leucine-rich repeat [structural motif]
    pfam17968
    Location:699 → 731
    Tlr3_TMD; Toll-like receptor 3 trans-membrane domain
Nucleotide Protein
Heading Accession and Version

Gene LinkOut

The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.