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IRF3 interferon regulatory factor 3 [ Canis lupus familiaris (dog) ]

Gene ID: 476412, updated on 5-Mar-2024

Summary

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Official Symbol
IRF3provided by VGNC
Official Full Name
interferon regulatory factor 3provided by VGNC
Primary source
VGNC:VGNC:54848
See related
Ensembl:ENSCAFG00845023315
Gene type
protein coding
RefSeq status
MODEL
Organism
Canis lupus familiaris (sub-species: familiaris)
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Carnivora; Caniformia; Canidae; Canis
Orthologs
human mouse all
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Genomic context

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Location:
chromosome: 1
Exon count:
8
Annotation release Status Assembly Chr Location
106 current ROS_Cfam_1.0 (GCF_014441545.1) 1 NC_051805.1 (107394678..107400508)
106 current Dog10K_Boxer_Tasha (GCF_000002285.5) 1 NC_006583.4 (106457016..106462843)
106 current UU_Cfam_GSD_1.0 (GCF_011100685.1) 1 NC_049222.1 (107550123..107555958)
106 current UMICH_Zoey_3.1 (GCF_005444595.1) 1 NC_049261.1 (107066914..107072739)
106 current UNSW_CanFamBas_1.0 (GCF_013276365.1) 1 NC_049742.1 (106709002..106714828)

Chromosome 1 - NC_051805.1Genomic Context describing neighboring genes Neighboring gene U4 spliceosomal RNA Neighboring gene BCL2 like 12 Neighboring gene SR-related CTD associated factor 1 Neighboring gene RAS related

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Identification and characterization of MAVS, a mitochondrial antiviral signaling protein that activates NF-kappaB and IRF 3. Seth RB, et al. Cell, 2005 Sep 9. PMID 16125763

GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables DNA-binding transcription factor activity, RNA polymerase II-specific IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables RNA polymerase II cis-regulatory region sequence-specific DNA binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables protein binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in immune system process IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in regulation of transcription by RNA polymerase II IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in nucleus IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
interferon regulatory factor 3

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Canis lupus familiaris Annotation Release 106 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference ROS_Cfam_1.0

Genomic

  1. NC_051805.1 Reference ROS_Cfam_1.0

    Range
    107394678..107400508
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038656303.1 → XP_038512231.1  interferon regulatory factor 3 isoform X1

    UniProtKB/TrEMBL
    A0A8C0LFY3, A0A8C0SWW9, A0A8C0SZ02, A0A8I3PLU0
    Conserved Domains (2) summary
    pfam00605
    Location:7 → 110
    IRF; Interferon regulatory factor transcription factor
    pfam10401
    Location:202 → 380
    IRF-3; Interferon-regulatory factor 3

  2. XM_038656302.1 → XP_038512230.1  interferon regulatory factor 3 isoform X1

    UniProtKB/TrEMBL
    A0A8C0LFY3, A0A8C0SWW9, A0A8C0SZ02, A0A8I3PLU0
    Related
    ENSCAFP00845032284.1, ENSCAFT00845041192.1
    Conserved Domains (2) summary
    pfam00605
    Location:7 → 110
    IRF; Interferon regulatory factor transcription factor
    pfam10401
    Location:202 → 380
    IRF-3; Interferon-regulatory factor 3

  3. XM_038656301.1 → XP_038512229.1  interferon regulatory factor 3 isoform X1

    UniProtKB/TrEMBL
    A0A8C0LFY3, A0A8C0SWW9, A0A8C0SZ02, A0A8I3PLU0
    Conserved Domains (2) summary
    pfam00605
    Location:7 → 110
    IRF; Interferon regulatory factor transcription factor
    pfam10401
    Location:202 → 380
    IRF-3; Interferon-regulatory factor 3

  4. XM_038656300.1 → XP_038512228.1  interferon regulatory factor 3 isoform X1

    UniProtKB/TrEMBL
    A0A8C0LFY3, A0A8C0SWW9, A0A8C0SZ02, A0A8I3PLU0
    Conserved Domains (2) summary
    pfam00605
    Location:7 → 110
    IRF; Interferon regulatory factor transcription factor
    pfam10401
    Location:202 → 380
    IRF-3; Interferon-regulatory factor 3

  5. XM_038656304.1 → XP_038512232.1  interferon regulatory factor 3 isoform X2

    Conserved Domains (1) summary
    pfam10401
    Location:56 → 234
    IRF-3; Interferon-regulatory factor 3

Alternate UMICH_Zoey_3.1

Genomic

  1. NC_049261.1 Alternate UMICH_Zoey_3.1

    Range
    107066914..107072739
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038467512.1 → XP_038323440.1  interferon regulatory factor 3 isoform X1

    Conserved Domains (2) summary
    pfam00605
    Location:7 → 110
    IRF; Interferon regulatory factor transcription factor
    pfam10401
    Location:202 → 380
    IRF-3; Interferon-regulatory factor 3

  2. XM_038467511.1 → XP_038323439.1  interferon regulatory factor 3 isoform X1

    Conserved Domains (2) summary
    pfam00605
    Location:7 → 110
    IRF; Interferon regulatory factor transcription factor
    pfam10401
    Location:202 → 380
    IRF-3; Interferon-regulatory factor 3

  3. XM_038467510.1 → XP_038323438.1  interferon regulatory factor 3 isoform X1

    Conserved Domains (2) summary
    pfam00605
    Location:7 → 110
    IRF; Interferon regulatory factor transcription factor
    pfam10401
    Location:202 → 380
    IRF-3; Interferon-regulatory factor 3

  4. XM_038467509.1 → XP_038323437.1  interferon regulatory factor 3 isoform X1

    Conserved Domains (2) summary
    pfam00605
    Location:7 → 110
    IRF; Interferon regulatory factor transcription factor
    pfam10401
    Location:202 → 380
    IRF-3; Interferon-regulatory factor 3

  5. XM_038467513.1 → XP_038323441.1  interferon regulatory factor 3 isoform X2

    Conserved Domains (1) summary
    pfam10401
    Location:56 → 234
    IRF-3; Interferon-regulatory factor 3

Alternate UNSW_CanFamBas_1.0

Genomic

  1. NC_049742.1 Alternate UNSW_CanFamBas_1.0

    Range
    106709002..106714828
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038592512.1 → XP_038448440.1  interferon regulatory factor 3 isoform X1

    Conserved Domains (2) summary
    pfam00605
    Location:7 → 110
    IRF; Interferon regulatory factor transcription factor
    pfam10401
    Location:202 → 380
    IRF-3; Interferon-regulatory factor 3

  2. XM_038592511.1 → XP_038448439.1  interferon regulatory factor 3 isoform X1

    Conserved Domains (2) summary
    pfam00605
    Location:7 → 110
    IRF; Interferon regulatory factor transcription factor
    pfam10401
    Location:202 → 380
    IRF-3; Interferon-regulatory factor 3

  3. XM_038592510.1 → XP_038448438.1  interferon regulatory factor 3 isoform X1

    Conserved Domains (2) summary
    pfam00605
    Location:7 → 110
    IRF; Interferon regulatory factor transcription factor
    pfam10401
    Location:202 → 380
    IRF-3; Interferon-regulatory factor 3

  4. XM_038592509.1 → XP_038448437.1  interferon regulatory factor 3 isoform X1

    Conserved Domains (2) summary
    pfam00605
    Location:7 → 110
    IRF; Interferon regulatory factor transcription factor
    pfam10401
    Location:202 → 380
    IRF-3; Interferon-regulatory factor 3

  5. XM_038592513.1 → XP_038448441.1  interferon regulatory factor 3 isoform X2

    Conserved Domains (1) summary
    pfam10401
    Location:56 → 234
    IRF-3; Interferon-regulatory factor 3

Alternate UU_Cfam_GSD_1.0

Genomic

  1. NC_049222.1 Alternate UU_Cfam_GSD_1.0

    Range
    107550123..107555958
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038528218.1 → XP_038384146.1  interferon regulatory factor 3 isoform X1

    UniProtKB/TrEMBL
    A0A8C0LFY3, A0A8C0SWW9, A0A8C0SZ02, A0A8I3PLU0
    Conserved Domains (2) summary
    pfam00605
    Location:7 → 110
    IRF; Interferon regulatory factor transcription factor
    pfam10401
    Location:202 → 380
    IRF-3; Interferon-regulatory factor 3

  2. XM_038528216.1 → XP_038384144.1  interferon regulatory factor 3 isoform X1

    UniProtKB/TrEMBL
    A0A8C0LFY3, A0A8C0SWW9, A0A8C0SZ02, A0A8I3PLU0
    Conserved Domains (2) summary
    pfam00605
    Location:7 → 110
    IRF; Interferon regulatory factor transcription factor
    pfam10401
    Location:202 → 380
    IRF-3; Interferon-regulatory factor 3

  3. XM_038528215.1 → XP_038384143.1  interferon regulatory factor 3 isoform X1

    UniProtKB/TrEMBL
    A0A8C0LFY3, A0A8C0SWW9, A0A8C0SZ02, A0A8I3PLU0
    Conserved Domains (2) summary
    pfam00605
    Location:7 → 110
    IRF; Interferon regulatory factor transcription factor
    pfam10401
    Location:202 → 380
    IRF-3; Interferon-regulatory factor 3

  4. XM_038528214.1 → XP_038384142.1  interferon regulatory factor 3 isoform X1

    UniProtKB/TrEMBL
    A0A8C0LFY3, A0A8C0SWW9, A0A8C0SZ02, A0A8I3PLU0
    Conserved Domains (2) summary
    pfam00605
    Location:7 → 110
    IRF; Interferon regulatory factor transcription factor
    pfam10401
    Location:202 → 380
    IRF-3; Interferon-regulatory factor 3

  5. XM_038528219.1 → XP_038384147.1  interferon regulatory factor 3 isoform X2

    Conserved Domains (1) summary
    pfam10401
    Location:56 → 234
    IRF-3; Interferon-regulatory factor 3

Alternate Dog10K_Boxer_Tasha Primary Assembly

Genomic

  1. NC_006583.4 Alternate Dog10K_Boxer_Tasha Primary Assembly

    Range
    106457016..106462843
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038671213.1 → XP_038527141.1  interferon regulatory factor 3 isoform X1

    UniProtKB/TrEMBL
    A0A8C0LFY3, A0A8C0SWW9, A0A8C0SZ02, A0A8I3PLU0
    Conserved Domains (2) summary
    pfam00605
    Location:7 → 110
    IRF; Interferon regulatory factor transcription factor
    pfam10401
    Location:202 → 380
    IRF-3; Interferon-regulatory factor 3

  2. XM_038671141.1 → XP_038527069.1  interferon regulatory factor 3 isoform X1

    UniProtKB/TrEMBL
    A0A8C0LFY3, A0A8C0SWW9, A0A8C0SZ02, A0A8I3PLU0
    Conserved Domains (2) summary
    pfam00605
    Location:7 → 110
    IRF; Interferon regulatory factor transcription factor
    pfam10401
    Location:202 → 380
    IRF-3; Interferon-regulatory factor 3

  3. XM_038671075.1 → XP_038527003.1  interferon regulatory factor 3 isoform X1

    UniProtKB/TrEMBL
    A0A8C0LFY3, A0A8C0SWW9, A0A8C0SZ02, A0A8I3PLU0
    Conserved Domains (2) summary
    pfam00605
    Location:7 → 110
    IRF; Interferon regulatory factor transcription factor
    pfam10401
    Location:202 → 380
    IRF-3; Interferon-regulatory factor 3

  4. XM_038671007.1 → XP_038526935.1  interferon regulatory factor 3 isoform X1

    UniProtKB/TrEMBL
    A0A8C0LFY3, A0A8C0SWW9, A0A8C0SZ02, A0A8I3PLU0
    Conserved Domains (2) summary
    pfam00605
    Location:7 → 110
    IRF; Interferon regulatory factor transcription factor
    pfam10401
    Location:202 → 380
    IRF-3; Interferon-regulatory factor 3

  5. XM_022423781.2 → XP_022279489.1  interferon regulatory factor 3 isoform X2

    Conserved Domains (1) summary
    pfam10401
    Location:56 → 234
    IRF-3; Interferon-regulatory factor 3
Nucleotide Protein
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