U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

MUS81 MUS81 structure-specific endonuclease subunit [ Canis lupus familiaris (dog) ]

Gene ID: 476021, updated on 5-Mar-2024

Summary

Go to the top of the page Help
Official Symbol
MUS81provided by VGNC
Official Full Name
MUS81 structure-specific endonuclease subunitprovided by VGNC
Primary source
VGNC:VGNC:43503
See related
Ensembl:ENSCAFG00845017866
Gene type
protein coding
RefSeq status
MODEL
Organism
Canis lupus familiaris (sub-species: familiaris)
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Carnivora; Caniformia; Canidae; Canis
Orthologs
human mouse all
NEW
Try the new Gene table
Try the new Transcript table

Genomic context

Go to the top of the page Help
See MUS81 in Genome Data Viewer
Location:
chromosome: 18
Exon count:
20
Annotation release Status Assembly Chr Location
106 current ROS_Cfam_1.0 (GCF_014441545.1) 18 NC_051822.1 (52434470..52442704, complement)
106 current Dog10K_Boxer_Tasha (GCF_000002285.5) 18 NC_006600.4 (50005016..50013354, complement)
106 current UU_Cfam_GSD_1.0 (GCF_011100685.1) 18 NC_049239.1 (51898219..51906443, complement)
106 current UMICH_Zoey_3.1 (GCF_005444595.1) 18 NC_049278.1 (51534536..51542760, complement)
106 current UNSW_CanFamBas_1.0 (GCF_013276365.1) 18 NC_049759.1 (51108911..51117134, complement)

Chromosome 18 - NC_051822.1Genomic Context describing neighboring genes Neighboring gene 40S ribosomal protein S15a-like Neighboring gene cathepsin W Neighboring gene EGF containing fibulin extracellular matrix protein 2 Neighboring gene cofilin 1 Neighboring gene sorting nexin 32 Neighboring gene ovo like transcriptional repressor 1 Neighboring gene adaptor related protein complex 5 subunit beta 1

Genomic regions, transcripts, and products

Go to the top of the page Help

Go to nucleotide: Graphics FASTA GenBank

Bibliography

Go to the top of the pageHelp

GeneRIFs: Gene References Into Functions

General gene information

Go to the top of the page Help

Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables 3'-flap endonuclease activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables DNA binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables crossover junction DNA endonuclease activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in DNA catabolic process IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in double-strand break repair via break-induced replication IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in mitotic intra-S DNA damage checkpoint signaling IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in resolution of meiotic recombination intermediates IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
part_of Holliday junction resolvase complex IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in nucleus IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

Go to the top of the page Help
Preferred Names
crossover junction endonuclease MUS81
Names
MUS81 endonuclease homolog
XP_005631508.1
XP_022261344.1
XP_022261345.1
XP_022261347.1
XP_022261348.1
XP_022261349.1
XP_022261350.1
XP_038280871.1
XP_038280872.1
XP_038280873.1
XP_038280874.1
XP_038280875.1
XP_038280876.1
XP_038280877.1
XP_038280878.1
XP_038280879.1
XP_038309650.1
XP_038357110.1
XP_038357111.1
XP_038357113.1
XP_038357114.1
XP_038357115.1
XP_038357116.1
XP_038357117.1
XP_038357118.1
XP_038357119.1
XP_038419811.1
XP_038419812.1
XP_038419813.1
XP_038419814.1
XP_038419815.1
XP_038419816.1
XP_038419817.1
XP_038419818.1
XP_038483937.1
XP_038483938.1
XP_038483939.1
XP_038483940.1
XP_038483941.1
XP_038483943.1
XP_038483944.1
XP_038483945.1
XP_038483946.1
XP_533230.2

NCBI Reference Sequences (RefSeq)

Go to the top of the page Help

NEW Try the new Transcript table

RefSeqs of Annotated Genomes: Canis lupus familiaris Annotation Release 106 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference ROS_Cfam_1.0

Genomic

  1. NC_051822.1 Reference ROS_Cfam_1.0

    Range
    52434470..52442704 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038424946.1 → XP_038280874.1  crossover junction endonuclease MUS81 isoform X3

    Conserved Domains (2) summary
    cd20074
    Location:349 → 499
    XPF_nuclease_Mus81; XPF-like nuclease domain of Mus81
    cd21036
    Location:168 → 301
    WH_MUS81; winged helix domain found in crossover junction endonuclease MUS81 and similar proteins

  2. XM_038424943.1 → XP_038280871.1  crossover junction endonuclease MUS81 isoform X1

    Conserved Domains (2) summary
    cd20074
    Location:349 → 499
    XPF_nuclease_Mus81; XPF-like nuclease domain of Mus81
    cd21036
    Location:168 → 301
    WH_MUS81; winged helix domain found in crossover junction endonuclease MUS81 and similar proteins

  3. XM_038424951.1 → XP_038280879.1  crossover junction endonuclease MUS81 isoform X7

    UniProtKB/TrEMBL
    A0A8I3P5T0
    Conserved Domains (2) summary
    cd20074
    Location:258 → 408
    XPF_nuclease_Mus81; XPF-like nuclease domain of Mus81
    cd21036
    Location:168 → 239
    WH_MUS81; winged helix domain found in crossover junction endonuclease MUS81 and similar proteins

  4. XM_038424947.1 → XP_038280875.1  crossover junction endonuclease MUS81 isoform X4

    UniProtKB/TrEMBL
    A0A8C0STK8
    Conserved Domains (2) summary
    cd20074
    Location:305 → 455
    XPF_nuclease_Mus81; XPF-like nuclease domain of Mus81
    cd21036
    Location:168 → 257
    WH_MUS81; winged helix domain found in crossover junction endonuclease MUS81 and similar proteins

  5. XM_038424949.1 → XP_038280877.1  crossover junction endonuclease MUS81 isoform X5

    UniProtKB/TrEMBL
    A0A8C0STK8
    Conserved Domains (2) summary
    cd20074
    Location:299 → 449
    XPF_nuclease_Mus81; XPF-like nuclease domain of Mus81
    cd21036
    Location:118 → 251
    WH_MUS81; winged helix domain found in crossover junction endonuclease MUS81 and similar proteins

  6. XM_038424948.1 → XP_038280876.1  crossover junction endonuclease MUS81 isoform X5

    UniProtKB/TrEMBL
    A0A8C0STK8
    Conserved Domains (2) summary
    cd20074
    Location:299 → 449
    XPF_nuclease_Mus81; XPF-like nuclease domain of Mus81
    cd21036
    Location:118 → 251
    WH_MUS81; winged helix domain found in crossover junction endonuclease MUS81 and similar proteins

  7. XM_038424944.1 → XP_038280872.1  crossover junction endonuclease MUS81 isoform X2

    UniProtKB/TrEMBL
    A0A8C0STK8
    Conserved Domains (2) summary
    cd20074
    Location:311 → 461
    XPF_nuclease_Mus81; XPF-like nuclease domain of Mus81
    cd21036
    Location:130 → 263
    WH_MUS81; winged helix domain found in crossover junction endonuclease MUS81 and similar proteins

  8. XM_038424945.1 → XP_038280873.1  crossover junction endonuclease MUS81 isoform X2

    UniProtKB/TrEMBL
    A0A8C0STK8
    Conserved Domains (2) summary
    cd20074
    Location:311 → 461
    XPF_nuclease_Mus81; XPF-like nuclease domain of Mus81
    cd21036
    Location:130 → 263
    WH_MUS81; winged helix domain found in crossover junction endonuclease MUS81 and similar proteins

  9. XM_038424950.1 → XP_038280878.1  crossover junction endonuclease MUS81 isoform X6

    UniProtKB/TrEMBL
    A0A8C0STK8
    Related
    ENSCAFP00845024761.1, ENSCAFT00845031636.1
    Conserved Domains (2) summary
    cd20074
    Location:267 → 417
    XPF_nuclease_Mus81; XPF-like nuclease domain of Mus81
    cd21036
    Location:130 → 219
    WH_MUS81; winged helix domain found in crossover junction endonuclease MUS81 and similar proteins

RNA

  1. XR_005296658.1 RNA Sequence

Alternate UMICH_Zoey_3.1

Genomic

  1. NC_049278.1 Alternate UMICH_Zoey_3.1

    Range
    51534536..51542760 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038501186.1 → XP_038357114.1  crossover junction endonuclease MUS81 isoform X3

    Conserved Domains (2) summary
    cd20074
    Location:349 → 499
    XPF_nuclease_Mus81; XPF-like nuclease domain of Mus81
    cd21036
    Location:168 → 301
    WH_MUS81; winged helix domain found in crossover junction endonuclease MUS81 and similar proteins

  2. XM_038501182.1 → XP_038357110.1  crossover junction endonuclease MUS81 isoform X1

    Conserved Domains (2) summary
    cd20074
    Location:349 → 499
    XPF_nuclease_Mus81; XPF-like nuclease domain of Mus81
    cd21036
    Location:168 → 301
    WH_MUS81; winged helix domain found in crossover junction endonuclease MUS81 and similar proteins

  3. XM_038501191.1 → XP_038357119.1  crossover junction endonuclease MUS81 isoform X7

    Conserved Domains (2) summary
    cd20074
    Location:258 → 408
    XPF_nuclease_Mus81; XPF-like nuclease domain of Mus81
    cd21036
    Location:168 → 239
    WH_MUS81; winged helix domain found in crossover junction endonuclease MUS81 and similar proteins

  4. XM_038501187.1 → XP_038357115.1  crossover junction endonuclease MUS81 isoform X4

    Conserved Domains (2) summary
    cd20074
    Location:305 → 455
    XPF_nuclease_Mus81; XPF-like nuclease domain of Mus81
    cd21036
    Location:168 → 257
    WH_MUS81; winged helix domain found in crossover junction endonuclease MUS81 and similar proteins

  5. XM_038501189.1 → XP_038357117.1  crossover junction endonuclease MUS81 isoform X5

    Conserved Domains (2) summary
    cd20074
    Location:299 → 449
    XPF_nuclease_Mus81; XPF-like nuclease domain of Mus81
    cd21036
    Location:118 → 251
    WH_MUS81; winged helix domain found in crossover junction endonuclease MUS81 and similar proteins

  6. XM_038501188.1 → XP_038357116.1  crossover junction endonuclease MUS81 isoform X5

    Conserved Domains (2) summary
    cd20074
    Location:299 → 449
    XPF_nuclease_Mus81; XPF-like nuclease domain of Mus81
    cd21036
    Location:118 → 251
    WH_MUS81; winged helix domain found in crossover junction endonuclease MUS81 and similar proteins

  7. XM_038501183.1 → XP_038357111.1  crossover junction endonuclease MUS81 isoform X2

    Conserved Domains (2) summary
    cd20074
    Location:311 → 461
    XPF_nuclease_Mus81; XPF-like nuclease domain of Mus81
    cd21036
    Location:130 → 263
    WH_MUS81; winged helix domain found in crossover junction endonuclease MUS81 and similar proteins

  8. XM_038501185.1 → XP_038357113.1  crossover junction endonuclease MUS81 isoform X2

    Conserved Domains (2) summary
    cd20074
    Location:311 → 461
    XPF_nuclease_Mus81; XPF-like nuclease domain of Mus81
    cd21036
    Location:130 → 263
    WH_MUS81; winged helix domain found in crossover junction endonuclease MUS81 and similar proteins

  9. XM_038501190.1 → XP_038357118.1  crossover junction endonuclease MUS81 isoform X6

    Conserved Domains (2) summary
    cd20074
    Location:267 → 417
    XPF_nuclease_Mus81; XPF-like nuclease domain of Mus81
    cd21036
    Location:130 → 219
    WH_MUS81; winged helix domain found in crossover junction endonuclease MUS81 and similar proteins

RNA

  1. XR_005339857.1 RNA Sequence

Alternate UNSW_CanFamBas_1.0

Genomic

  1. NC_049759.1 Alternate UNSW_CanFamBas_1.0

    Range
    51108911..51117134 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038628012.1 → XP_038483940.1  crossover junction endonuclease MUS81 isoform X3

  2. XM_038628009.1 → XP_038483937.1  crossover junction endonuclease MUS81 isoform X1

  3. XM_038628018.1 → XP_038483946.1  crossover junction endonuclease MUS81 isoform X7

  4. XM_038628013.1 → XP_038483941.1  crossover junction endonuclease MUS81 isoform X4

  5. XM_038628016.1 → XP_038483944.1  crossover junction endonuclease MUS81 isoform X5

  6. XM_038628015.1 → XP_038483943.1  crossover junction endonuclease MUS81 isoform X5

  7. XM_038628010.1 → XP_038483938.1  crossover junction endonuclease MUS81 isoform X2

  8. XM_038628011.1 → XP_038483939.1  crossover junction endonuclease MUS81 isoform X2

  9. XM_038628017.1 → XP_038483945.1  crossover junction endonuclease MUS81 isoform X6

RNA

  1. XR_005407682.1 RNA Sequence

Alternate UU_Cfam_GSD_1.0

Genomic

  1. NC_049239.1 Alternate UU_Cfam_GSD_1.0

    Range
    51898219..51906443 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038563885.1 → XP_038419813.1  crossover junction endonuclease MUS81 isoform X3

    Conserved Domains (2) summary
    cd20074
    Location:349 → 499
    XPF_nuclease_Mus81; XPF-like nuclease domain of Mus81
    cd21036
    Location:168 → 301
    WH_MUS81; winged helix domain found in crossover junction endonuclease MUS81 and similar proteins

  2. XM_038563883.1 → XP_038419811.1  crossover junction endonuclease MUS81 isoform X1

    Conserved Domains (2) summary
    cd20074
    Location:349 → 499
    XPF_nuclease_Mus81; XPF-like nuclease domain of Mus81
    cd21036
    Location:168 → 301
    WH_MUS81; winged helix domain found in crossover junction endonuclease MUS81 and similar proteins

  3. XM_038563890.1 → XP_038419818.1  crossover junction endonuclease MUS81 isoform X7

    UniProtKB/TrEMBL
    A0A8I3P5T0
    Conserved Domains (2) summary
    cd20074
    Location:258 → 408
    XPF_nuclease_Mus81; XPF-like nuclease domain of Mus81
    cd21036
    Location:168 → 239
    WH_MUS81; winged helix domain found in crossover junction endonuclease MUS81 and similar proteins

  4. XM_038563886.1 → XP_038419814.1  crossover junction endonuclease MUS81 isoform X4

    UniProtKB/TrEMBL
    A0A8C0STK8
    Conserved Domains (2) summary
    cd20074
    Location:305 → 455
    XPF_nuclease_Mus81; XPF-like nuclease domain of Mus81
    cd21036
    Location:168 → 257
    WH_MUS81; winged helix domain found in crossover junction endonuclease MUS81 and similar proteins

  5. XM_038563888.1 → XP_038419816.1  crossover junction endonuclease MUS81 isoform X5

    UniProtKB/TrEMBL
    A0A8C0STK8
    Conserved Domains (2) summary
    cd20074
    Location:299 → 449
    XPF_nuclease_Mus81; XPF-like nuclease domain of Mus81
    cd21036
    Location:118 → 251
    WH_MUS81; winged helix domain found in crossover junction endonuclease MUS81 and similar proteins

  6. XM_038563887.1 → XP_038419815.1  crossover junction endonuclease MUS81 isoform X5

    UniProtKB/TrEMBL
    A0A8C0STK8
    Conserved Domains (2) summary
    cd20074
    Location:299 → 449
    XPF_nuclease_Mus81; XPF-like nuclease domain of Mus81
    cd21036
    Location:118 → 251
    WH_MUS81; winged helix domain found in crossover junction endonuclease MUS81 and similar proteins

  7. XM_038563884.1 → XP_038419812.1  crossover junction endonuclease MUS81 isoform X2

    UniProtKB/TrEMBL
    A0A8C0STK8
    Conserved Domains (2) summary
    cd20074
    Location:311 → 461
    XPF_nuclease_Mus81; XPF-like nuclease domain of Mus81
    cd21036
    Location:130 → 263
    WH_MUS81; winged helix domain found in crossover junction endonuclease MUS81 and similar proteins

  8. XM_038563889.1 → XP_038419817.1  crossover junction endonuclease MUS81 isoform X6

    UniProtKB/TrEMBL
    A0A8C0STK8
    Conserved Domains (2) summary
    cd20074
    Location:267 → 417
    XPF_nuclease_Mus81; XPF-like nuclease domain of Mus81
    cd21036
    Location:130 → 219
    WH_MUS81; winged helix domain found in crossover junction endonuclease MUS81 and similar proteins

RNA

  1. XR_005373620.1 RNA Sequence

Alternate Dog10K_Boxer_Tasha Primary Assembly

Genomic

  1. NC_006600.4 Alternate Dog10K_Boxer_Tasha Primary Assembly

    Range
    50005016..50013354 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_022405639.2 → XP_022261347.1  crossover junction endonuclease MUS81 isoform X3

    Conserved Domains (1) summary
    pfam02732
    Location:356 → 498
    ERCC4; ERCC4 domain

  2. XM_022405636.2 → XP_022261344.1  crossover junction endonuclease MUS81 isoform X1

    Conserved Domains (1) summary
    pfam02732
    Location:356 → 498
    ERCC4; ERCC4 domain

  3. XM_022405642.2 → XP_022261350.1  crossover junction endonuclease MUS81 isoform X7

    UniProtKB/TrEMBL
    A0A8P0PK89
    Conserved Domains (1) summary
    pfam02732
    Location:265 → 407
    ERCC4; ERCC4 domain

  4. XM_005631451.4 → XP_005631508.1  crossover junction endonuclease MUS81 isoform X4

    UniProtKB/TrEMBL
    A0A8P0TNY4
    Conserved Domains (1) summary
    pfam02732
    Location:312 → 454
    ERCC4; ERCC4 domain

  5. XM_022405641.2 → XP_022261349.1  crossover junction endonuclease MUS81 isoform X5

    UniProtKB/TrEMBL
    A0A8P0TNY4
    Conserved Domains (1) summary
    pfam02732
    Location:306 → 448
    ERCC4; ERCC4 domain

  6. XM_022405640.2 → XP_022261348.1  crossover junction endonuclease MUS81 isoform X5

    UniProtKB/TrEMBL
    A0A8P0TNY4
    Conserved Domains (1) summary
    pfam02732
    Location:306 → 448
    ERCC4; ERCC4 domain

  7. XM_022405637.2 → XP_022261345.1  crossover junction endonuclease MUS81 isoform X2

    UniProtKB/TrEMBL
    A0A8P0TNY4
    Conserved Domains (2) summary
    cd20074
    Location:311 → 461
    XPF_nuclease_Mus81; XPF-like nuclease domain of Mus81
    cd21036
    Location:130 → 263
    WH_MUS81; winged helix domain found in crossover junction endonuclease MUS81 and similar proteins

  8. XM_038453722.1 → XP_038309650.1  crossover junction endonuclease MUS81 isoform X2

    UniProtKB/TrEMBL
    A0A8P0TNY4
    Conserved Domains (2) summary
    cd20074
    Location:311 → 461
    XPF_nuclease_Mus81; XPF-like nuclease domain of Mus81
    cd21036
    Location:130 → 263
    WH_MUS81; winged helix domain found in crossover junction endonuclease MUS81 and similar proteins

  9. XM_533230.7 → XP_533230.2  crossover junction endonuclease MUS81 isoform X6

    UniProtKB/TrEMBL
    A0A8P0TNY4
    Conserved Domains (1) summary
    pfam02732
    Location:274 → 416
    ERCC4; ERCC4 domain

RNA

  1. XR_002616042.2 RNA Sequence

Nucleotide Protein
Heading Accession and Version

Gene LinkOut

The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

Molecular Biology Databases
Research Materials
Miscellaneous