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PTGR1 prostaglandin reductase 1 [ Canis lupus familiaris (dog) ]

Gene ID: 474802, updated on 5-Mar-2024

Summary

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Official Symbol
PTGR1provided by VGNC
Official Full Name
prostaglandin reductase 1provided by VGNC
Primary source
VGNC:VGNC:45150
See related
Ensembl:ENSCAFG00845005537
Gene type
protein coding
RefSeq status
MODEL
Organism
Canis lupus familiaris (sub-species: familiaris)
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Carnivora; Caniformia; Canidae; Canis
Also known as
LTB4DH
Orthologs
human mouse all
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Genomic context

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Location:
chromosome: 11
Exon count:
12
Annotation release Status Assembly Chr Location
106 current ROS_Cfam_1.0 (GCF_014441545.1) 11 NC_051815.1 (67324103..67345145, complement)
106 current Dog10K_Boxer_Tasha (GCF_000002285.5) 11 NC_006593.4 (64601934..64622894, complement)
106 current UU_Cfam_GSD_1.0 (GCF_011100685.1) 11 NC_049232.1 (66554733..66575785, complement)
106 current UMICH_Zoey_3.1 (GCF_005444595.1) 11 NC_049271.1 (65841533..65862116, complement)
106 current UNSW_CanFamBas_1.0 (GCF_013276365.1) 11 NC_049752.1 (65864869..65885860, complement)

Chromosome 11 - NC_051815.1Genomic Context describing neighboring genes Neighboring gene Ecm29 proteasome adaptor and scaffold Neighboring gene zinc finger protein 483 Neighboring gene uncharacterized LOC111097881 Neighboring gene DnaJ heat shock protein family (Hsp40) member C25 Neighboring gene uncharacterized LOC119873977

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables 15-oxoprostaglandin 13-oxidase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables 2-alkenal reductase [NAD(P)+] activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in prostaglandin metabolic process IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in cytoplasm IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
LOW QUALITY PROTEIN: prostaglandin reductase 1; prostaglandin reductase 1
Names
leukotriene B4 12-hydroxydehydrogenase
XP_005626979.1
XP_038346893.1
XP_038409032.1
XP_038409033.1
XP_038472907.1
XP_038472908.1
XP_038509830.1
XP_038538367.1
XP_038538368.1

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Canis lupus familiaris Annotation Release 106 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference ROS_Cfam_1.0

Genomic

  1. NC_051815.1 Reference ROS_Cfam_1.0

    Range
    67324103..67345145 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038682439.1 → XP_038538367.1  prostaglandin reductase 1

    UniProtKB/TrEMBL
    A0A8C0MR59, A0A8C0MZC4, A0A8I3MRC0
    Conserved Domains (1) summary
    TIGR02825
    Location:4 → 328
    B4_12hDH; leukotriene B4 12-hydroxydehydrogenase/15-oxo-prostaglandin 13-reductase

  2. XM_038682440.1 → XP_038538368.1  prostaglandin reductase 1

    UniProtKB/TrEMBL
    A0A8C0MR59, A0A8C0MZC4, A0A8I3MRC0
    Related
    ENSCAFP00845007696.1, ENSCAFT00845009852.1
    Conserved Domains (1) summary
    TIGR02825
    Location:4 → 328
    B4_12hDH; leukotriene B4 12-hydroxydehydrogenase/15-oxo-prostaglandin 13-reductase

Alternate UMICH_Zoey_3.1

Genomic

  1. NC_049271.1 Alternate UMICH_Zoey_3.1

    Range
    65841533..65862116 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038490965.1 → XP_038346893.1  LOW QUALITY PROTEIN: prostaglandin reductase 1

Alternate UNSW_CanFamBas_1.0

Genomic

  1. NC_049752.1 Alternate UNSW_CanFamBas_1.0

    Range
    65864869..65885860 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038616979.1 → XP_038472907.1  prostaglandin reductase 1

  2. XM_038616980.1 → XP_038472908.1  prostaglandin reductase 1

Alternate UU_Cfam_GSD_1.0

Genomic

  1. NC_049232.1 Alternate UU_Cfam_GSD_1.0

    Range
    66554733..66575785 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038553104.1 → XP_038409032.1  prostaglandin reductase 1

    UniProtKB/TrEMBL
    A0A8C0MR59, A0A8C0MZC4, A0A8I3MRC0
    Conserved Domains (1) summary
    TIGR02825
    Location:4 → 328
    B4_12hDH; leukotriene B4 12-hydroxydehydrogenase/15-oxo-prostaglandin 13-reductase

  2. XM_038553105.1 → XP_038409033.1  prostaglandin reductase 1

    UniProtKB/TrEMBL
    A0A8C0MR59, A0A8C0MZC4, A0A8I3MRC0
    Conserved Domains (1) summary
    TIGR02825
    Location:4 → 328
    B4_12hDH; leukotriene B4 12-hydroxydehydrogenase/15-oxo-prostaglandin 13-reductase

Alternate Dog10K_Boxer_Tasha Primary Assembly

Genomic

  1. NC_006593.4 Alternate Dog10K_Boxer_Tasha Primary Assembly

    Range
    64601934..64622894 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038653902.1 → XP_038509830.1  prostaglandin reductase 1

    UniProtKB/TrEMBL
    A0A8C0MR59, A0A8C0MZC4, A0A8I3MRC0
    Conserved Domains (1) summary
    TIGR02825
    Location:4 → 328
    B4_12hDH; leukotriene B4 12-hydroxydehydrogenase/15-oxo-prostaglandin 13-reductase

  2. XM_005626922.4 → XP_005626979.1  prostaglandin reductase 1

    See identical proteins and their annotated locations for XP_005626979.1

    UniProtKB/TrEMBL
    A0A8C0MR59, A0A8C0MZC4, A0A8I3MRC0
    Conserved Domains (1) summary
    TIGR02825
    Location:4 → 328
    B4_12hDH; leukotriene B4 12-hydroxydehydrogenase/15-oxo-prostaglandin 13-reductase
Nucleotide Protein
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