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ebo ellipsoid body open [ Drosophila melanogaster (fruit fly) ]

Gene ID: 47141, updated on 27-Mar-2024

Summary

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Official Symbol
eboprovided by FlyBase
Official Full Name
ellipsoid body openprovided by FlyBase
Primary source
FLYBASE:FBgn0266572
Locus tag
Dmel_CG3923
See related
AllianceGenome:FB:FBgn0266572
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Drosophila melanogaster
Lineage
Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
Also known as
CG3923; Dmel\CG3923; EBO; EG:165H7.3; Exp1; exp6; Exp6
Summary
Predicted to enable nuclear export signal receptor activity and small GTPase binding activity. Involved in brain development; flight behavior; and short-term memory. Orthologous to human XPO6 (exportin 6). [provided by Alliance of Genome Resources, Apr 2022]
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Genomic context

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Location:
1B4-1B4; 1-0 cM
Exon count:
11
Annotation release Status Assembly Chr Location
Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) X NC_004354.4 (471019..476579, complement)
Release 5.57 previous assembly Release 5 (GCF_000001215.2) X NC_004354.3 (365052..370612, complement)

Chromosome X - NC_004354.4Genomic Context describing neighboring genes Neighboring gene uncharacterized protein Neighboring gene Cytochrome P450 4g1 Neighboring gene asense Neighboring gene pseudo Neighboring gene uncharacterized protein Neighboring gene uncharacterized protein Neighboring gene pseudo

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. The central complex of Drosophila melanogaster is involved in flight control: studies on mutants and mosaics of the gene ellipsoid body open. Ilius M, et al. J Neurogenet, 1994 Jul. PMID 7965387
  2. The central complex of Drosophila melanogaster is involved in flight control: studies on mutants and mosaics of the gene ellipsoid body open. Ilius M, et al. J Neurogenet, 2007 Oct-Dec. PMID 18161592
  3. Prostaglandins limit nuclear actin to control nucleolar function during oogenesis. Talbot DE, et al. Front Cell Dev Biol, 2023. PMID 36875757, Free PMC Article
  4. Mushroom bodies modulate salience-based selective fixation behavior in Drosophila. Xi W, et al. Eur J Neurosci, 2008 Mar. PMID 18364023
  5. Analysis of a spatial orientation memory in Drosophila. Neuser K, et al. Nature, 2008 Jun 26. PMID 18509336

See all (58) citations in PubMed

GeneRIFs: Gene References Into Functions

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Homology

Gene Ontology Provided by FlyBase

Function Evidence Code Pubs
enables nuclear export signal receptor activity IEA
Inferred from Electronic Annotation
more info
  
enables small GTPase binding IEA
Inferred from Electronic Annotation
more info
  
Process Evidence Code Pubs
involved_in adult walking behavior TAS
Traceable Author Statement
more info
 PubMed 
involved_in central complex development IMP
Inferred from Mutant Phenotype
more info
 PubMed 
involved_in flight behavior IMP
Inferred from Mutant Phenotype
more info
 PubMed 
involved_in intracellular protein transport IEA
Inferred from Electronic Annotation
more info
  
involved_in mushroom body development IMP
Inferred from Mutant Phenotype
more info
 PubMed 
involved_in protein export from nucleus IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in protein export from nucleus IEA
Inferred from Electronic Annotation
more info
  
involved_in short-term memory IMP
Inferred from Mutant Phenotype
more info
 PubMed 

General protein information

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Preferred Names
ellipsoid body open
Names
CG3923-PA
CG3923-PB
CG3923-PC
Exportin-6
ebo-PA
ebo-PB
ebo-PC
ellipsoid-body-open
exportin 6

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_004354.4 Reference assembly

    Range
    471019..476579 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_080140.3 → NP_524879.2  ellipsoid body open, isoform A [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_524879.2

    Status: REVIEWED

    UniProtKB/TrEMBL
    Q8T9F5, Q9W5G1
    Related
    FBpp0070093
    Conserved Domains (2) summary
    pfam03810
    Location:30 → 98
    IBN_N; Importin-beta N-terminal domain
    pfam08389
    Location:110 → 259
    Xpo1; Exportin 1-like protein

  2. NM_001297810.1 → NP_001284739.1  ellipsoid body open, isoform C [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_001284739.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    Q8T9F5, X2J9Y4
    Conserved Domains (2) summary
    pfam03810
    Location:30 → 98
    IBN_N; Importin-beta N-terminal domain
    pfam08389
    Location:110 → 259
    Xpo1; Exportin 1-like protein

  3. NM_001297809.1 → NP_001284738.1  ellipsoid body open, isoform B [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_001284738.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    Q8T9F5, X2JDN0
    Conserved Domains (2) summary
    pfam03810
    Location:30 → 98
    IBN_N; Importin-beta N-terminal domain
    pfam08389
    Location:110 → 259
    Xpo1; Exportin 1-like protein
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
O46055 O46055
Q8T9F5 Q8T9F5
Q9W5G1 Q9W5G1
X2J9Y4 X2J9Y4
X2JDN0 X2JDN0

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