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Krt27 keratin 27 [ Rattus norvegicus (Norway rat) ]

Gene ID: 450229, updated on 5-Mar-2024

Summary

Official Symbol
Krt27provided by RGD
Official Full Name
keratin 27provided by RGD
Primary source
RGD:1359115
See related
Ensembl:ENSRNOG00000011628 AllianceGenome:RGD:1359115
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Rattus norvegicus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
Also known as
Ka40
Summary
Predicted to enable structural molecule activity. Predicted to act upstream of or within hair follicle morphogenesis. Predicted to be located in cytoplasm and intermediate filament. Orthologous to human KRT27 (keratin 27). [provided by Alliance of Genome Resources, Apr 2022]
Expression
Restricted expression toward (RPKM 40.4) See more
Orthologs
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Genomic context

Location:
10q31
Exon count:
8
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCr8 (GCF_036323735.1) 10 NC_086028.1 (84794848..84800131, complement)
RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 10 NC_051345.1 (84298684..84303967, complement)
106 previous assembly Rnor_6.0 (GCF_000001895.5) 10 NC_005109.4 (87256434..87261717, complement)

Chromosome 10 - NC_086028.1Genomic Context describing neighboring genes Neighboring gene keratin 25 Neighboring gene keratin 26 Neighboring gene uncharacterized LOC108352132 Neighboring gene keratin 28 Neighboring gene uncharacterized LOC134480872 Neighboring gene keratin 10

Genomic regions, transcripts, and products

Expression

  • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
  • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
  • BioProject: PRJNA238328
  • Publication: PMID 24510058
  • Analysis date: Mon Jun 6 17:44:12 2016

General gene information

Gene Ontology Provided by RGD

Function Evidence Code Pubs
enables structural molecule activity IEA
Inferred from Electronic Annotation
more info
 
Process Evidence Code Pubs
involved_in epithelial cell differentiation IBA
Inferred from Biological aspect of Ancestor
more info
 
involved_in hair follicle morphogenesis IBA
Inferred from Biological aspect of Ancestor
more info
 
acts_upstream_of_or_within hair follicle morphogenesis ISO
Inferred from Sequence Orthology
more info
 
involved_in intermediate filament organization IBA
Inferred from Biological aspect of Ancestor
more info
 
Component Evidence Code Pubs
located_in cytoplasm IEA
Inferred from Electronic Annotation
more info
 
is_active_in cytoskeleton IBA
Inferred from Biological aspect of Ancestor
more info
 
located_in intermediate filament IEA
Inferred from Electronic Annotation
more info
 

General protein information

Preferred Names
keratin, type I cytoskeletal 27
Names
CK-27
K27
cytokeratin-27
keratin 27, type I
type I inner root sheath-specific keratin-K25irs3
type I keratin KA40

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001008824.1NP_001008824.1  keratin, type I cytoskeletal 27

    See identical proteins and their annotated locations for NP_001008824.1

    Status: PROVISIONAL

    Source sequence(s)
    BK004030
    UniProtKB/Swiss-Prot
    Q6IFW8
    UniProtKB/TrEMBL
    A6HIX6
    Related
    ENSRNOP00000015740.4, ENSRNOT00000015740.6
    Conserved Domains (2) summary
    pfam00038
    Location:73386
    Filament; Intermediate filament protein
    pfam11068
    Location:333376
    YlqD; YlqD protein

RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCr8

Genomic

  1. NC_086028.1 Reference GRCr8

    Range
    84794848..84800131 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)