U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

ATP4A ATPase H+/K+ transporting subunit alpha [ Canis lupus familiaris (dog) ]

Gene ID: 431686, updated on 5-Mar-2024

Summary

Go to the top of the page Help
Official Symbol
ATP4Aprovided by VGNC
Official Full Name
ATPase H+/K+ transporting subunit alphaprovided by VGNC
Primary source
VGNC:VGNC:38262
See related
Ensembl:ENSCAFG00845002265
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Canis lupus familiaris (sub-species: familiaris)
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Carnivora; Caniformia; Canidae; Canis
Orthologs
human mouse all
NEW
Try the new Gene table
Try the new Transcript table

Genomic context

Go to the top of the page Help
Location:
chromosome: 1
Exon count:
22
Annotation release Status Assembly Chr Location
106 current ROS_Cfam_1.0 (GCF_014441545.1) 1 NC_051805.1 (117705000..117716940)
106 current Dog10K_Boxer_Tasha (GCF_000002285.5) 1 NC_006583.4 (116507704..116519874)
106 current UU_Cfam_GSD_1.0 (GCF_011100685.1) 1 NC_049222.1 (117949139..117961076)
106 current UMICH_Zoey_3.1 (GCF_005444595.1) 1 NC_049261.1 (117267860..117280034)
106 current UNSW_CanFamBas_1.0 (GCF_013276365.1) 1 NC_049742.1 (116893656..116905826)

Chromosome 1 - NC_051805.1Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC111090112 Neighboring gene uncharacterized LOC102151354 Neighboring gene uncharacterized LOC111090505 Neighboring gene uncharacterized LOC119869726 Neighboring gene transmembrane protein 147 Neighboring gene glyceraldehyde-3-phosphate dehydrogenase, spermatogenic

Genomic regions, transcripts, and products

Go to the top of the page Help

Go to nucleotide: Graphics FASTA GenBank

Bibliography

Go to the top of the pageHelp

Related articles in PubMed

  1. Molecular cloning and structural analysis of canine gastric H+,K(+)-ATPase. Song I, et al. Biochem Biophys Res Commun, 1993 Nov 15. PMID 8250881

GeneRIFs: Gene References Into Functions

General gene information

Go to the top of the page Help

Markers

Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables ATP binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables ATP hydrolysis activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables P-type potassium:proton transporter activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables P-type sodium:potassium-exchanging transporter activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables magnesium ion binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in intracellular potassium ion homeostasis IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in intracellular sodium ion homeostasis IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in potassium ion import across plasma membrane IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in proton transmembrane transport IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in sodium ion export across plasma membrane IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in membrane IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

Go to the top of the page Help
Preferred Names
potassium-transporting ATPase alpha chain 1
Names
ATPase H+/K+ transporting alpha subunit
H /K exchanging ATPase alpha
H+/K+ exchanging ATPase alpha polypeptide
gastric H(+)/K(+) ATPase subunit alpha
proton pump
NP_001003342.1
XP_038509369.1

NCBI Reference Sequences (RefSeq)

Go to the top of the page Help

NEW Try the new Transcript table

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001003342.1 → NP_001003342.1  potassium-transporting ATPase alpha chain 1

    See identical proteins and their annotated locations for NP_001003342.1

    Status: PROVISIONAL

    Source sequence(s)
    L11568
    UniProtKB/Swiss-Prot
    P50996
    UniProtKB/TrEMBL
    A0A8C0MLS7, A0A8I3RQM6
    Related
    ENSCAFP00845003302.1, ENSCAFT00845004125.1
    Conserved Domains (7) summary
    smart00831
    Location:50 → 124
    Cation_ATPase_N; Cation transporter/ATPase, N-terminus
    COG4087
    Location:616 → 742
    COG4087; Soluble P-type ATPase [General function prediction only]
    TIGR01106
    Location:42 → 1034
    ATPase-IIC_X-K; sodium or proton efflux -- potassium uptake antiporter, P-type ATPase, alpha subunit
    pfam00122
    Location:145 → 375
    E1-E2_ATPase; E1-E2 ATPase
    pfam00689
    Location:809 → 1018
    Cation_ATPase_C; Cation transporting ATPase, C-terminus
    pfam09040
    Location:2 → 22
    H-K_ATPase_N; Gastric H+/K+-ATPase, N terminal domain
    pfam13246
    Location:437 → 531
    Cation_ATPase; Cation transport ATPase (P-type)

RefSeqs of Annotated Genomes: Canis lupus familiaris Annotation Release 106 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference ROS_Cfam_1.0

Genomic

  1. NC_051805.1 Reference ROS_Cfam_1.0

    Range
    117705000..117716940
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038653441.1 → XP_038509369.1  potassium-transporting ATPase alpha chain 1 isoform X1

    UniProtKB/TrEMBL
    A0A8C0MLS7, A0A8I3RQM6
    Related
    ENSCAFP00845003295.1, ENSCAFT00845004118.1
    Conserved Domains (2) summary
    TIGR01106
    Location:41 → 1033
    ATPase-IIC_X-K; sodium or proton efflux -- potassium uptake antiporter, P-type ATPase, alpha subunit
    pfam09040
    Location:4 → 21
    H-K_ATPase_N; Gastric H+/K+-ATPase, N terminal domain

Alternate UMICH_Zoey_3.1

Genomic

  1. NC_049261.1 Alternate UMICH_Zoey_3.1

    Range
    117267860..117280034
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

Alternate UNSW_CanFamBas_1.0

Genomic

  1. NC_049742.1 Alternate UNSW_CanFamBas_1.0

    Range
    116893656..116905826
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

Alternate UU_Cfam_GSD_1.0

Genomic

  1. NC_049222.1 Alternate UU_Cfam_GSD_1.0

    Range
    117949139..117961076
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

Alternate Dog10K_Boxer_Tasha Primary Assembly

Genomic

  1. NC_006583.4 Alternate Dog10K_Boxer_Tasha Primary Assembly

    Range
    116507704..116519874
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
P50996.3 GenPept UniProtKB/Swiss-Prot:P50996

Gene LinkOut

The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

Molecular Biology Databases
Research Materials
Miscellaneous