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AFDN afadin, adherens junction formation factor [ Gallus gallus (chicken) ]

Gene ID: 421564, updated on 3-Apr-2024

Summary

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Symbol
AFDNprovided by CGNC
Full Name
afadin, adherens junction formation factorprovided by CGNC
Primary source
CGNC:51504
See related
Ensembl:ENSGALG00010004951
Gene type
protein coding
RefSeq status
MODEL
Organism
Gallus gallus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda; Coelurosauria; Aves; Neognathae; Galloanserae; Galliformes; Phasianidae; Phasianinae; Gallus
Also known as
MLLT4
Orthologs
human mouse all
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Genomic context

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Location:
chromosome: 3
Exon count:
37
Annotation release Status Assembly Chr Location
106 current bGalGal1.mat.broiler.GRCg7b (GCF_016699485.2) 3 NC_052534.1 (41790522..41901208, complement)
106 current bGalGal1.pat.whiteleghornlayer.GRCg7w (GCF_016700215.2) 3 NC_052575.1 (41693640..41807840, complement)

Chromosome 3 - NC_052534.1Genomic Context describing neighboring genes Neighboring gene FERM domain containing 1 Neighboring gene uncharacterized LOC107053039 Neighboring gene kinesin family member 25 Neighboring gene uncharacterized LOC121110504 Neighboring gene uncharacterized LOC107053038 Neighboring gene uncharacterized LOC124418338 Neighboring gene uncharacterized LOC121110505 Neighboring gene unc-93 homolog A

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables cell adhesion molecule binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in regulation of protein localization IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in signal transduction IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in adherens junction IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
afadin
Names
myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 4
myeloid/lymphoid or mixed-lineage leukemia; translocated to, 4

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Gallus gallus Annotation Release 106 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference bGalGal1.mat.broiler.GRCg7b Primary Assembly

Genomic

  1. NC_052534.1 Reference bGalGal1.mat.broiler.GRCg7b Primary Assembly

    Range
    41790522..41901208 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_015284360.4 → XP_015139846.2  afadin isoform X27

    UniProtKB/TrEMBL
    A0A8V0XQW9
    Conserved Domains (6) summary
    cd00060
    Location:385 → 485
    FHA; Forkhead associated domain (FHA); found in eukaryotic and prokaryotic proteins. Putative nuclear signalling domain. FHA domains may bind phosphothreonine, phosphoserine and sometimes phosphotyrosine. In eukaryotes, many FHA domain-containing proteins ...
    cd00992
    Location:993 → 1076
    PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
    cd15471
    Location:597 → 918
    Myo5p-like_CBD_afadin; cargo binding domain of myosin 5-like of afadin
    cd01781
    Location:248 → 348
    RA2_Afadin; Ras-associating (RA) domain 2 found in Afadin
    cd01782
    Location:21 → 132
    RA1_Afadin; Ras-associating (RA) domain 1 found in Afadin
    pfam17380
    Location:1473 → 1616
    DUF5401; Family of unknown function (DUF5401)

  2. XM_040698600.2 → XP_040554534.1  afadin isoform X19

    UniProtKB/TrEMBL
    A0A8V0XQW9
    Conserved Domains (5) summary
    cd00060
    Location:418 → 500
    FHA; Forkhead associated domain (FHA); found in eukaryotic and prokaryotic proteins. Putative nuclear signalling domain. FHA domains may bind phosphothreonine, phosphoserine and sometimes phosphotyrosine. In eukaryotes, many FHA domain-containing proteins ...
    cd00992
    Location:1008 → 1091
    PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
    cd15471
    Location:612 → 933
    Myo5p-like_CBD_afadin; cargo binding domain of myosin 5-like of afadin
    cd01781
    Location:248 → 348
    RA2_Afadin; Ras-associating (RA) domain 2 found in Afadin
    cd01782
    Location:21 → 132
    RA1_Afadin; Ras-associating (RA) domain 1 found in Afadin

  3. XM_015284353.4 → XP_015139839.2  afadin isoform X10

    UniProtKB/TrEMBL
    A0A8V0XL29
    Conserved Domains (5) summary
    cd00060
    Location:418 → 500
    FHA; Forkhead associated domain (FHA); found in eukaryotic and prokaryotic proteins. Putative nuclear signalling domain. FHA domains may bind phosphothreonine, phosphoserine and sometimes phosphotyrosine. In eukaryotes, many FHA domain-containing proteins ...
    cd00992
    Location:1008 → 1091
    PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
    cd15471
    Location:612 → 933
    Myo5p-like_CBD_afadin; cargo binding domain of myosin 5-like of afadin
    cd01781
    Location:248 → 348
    RA2_Afadin; Ras-associating (RA) domain 2 found in Afadin
    cd01782
    Location:21 → 132
    RA1_Afadin; Ras-associating (RA) domain 1 found in Afadin

  4. XM_015284355.4 → XP_015139841.2  afadin isoform X17

    UniProtKB/TrEMBL
    A0A8V0XQW9
    Conserved Domains (5) summary
    cd00060
    Location:418 → 500
    FHA; Forkhead associated domain (FHA); found in eukaryotic and prokaryotic proteins. Putative nuclear signalling domain. FHA domains may bind phosphothreonine, phosphoserine and sometimes phosphotyrosine. In eukaryotes, many FHA domain-containing proteins ...
    cd00992
    Location:1008 → 1091
    PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
    cd15471
    Location:612 → 933
    Myo5p-like_CBD_afadin; cargo binding domain of myosin 5-like of afadin
    cd01781
    Location:248 → 348
    RA2_Afadin; Ras-associating (RA) domain 2 found in Afadin
    cd01782
    Location:21 → 132
    RA1_Afadin; Ras-associating (RA) domain 1 found in Afadin

  5. XM_040698598.2 → XP_040554532.1  afadin isoform X15

    UniProtKB/TrEMBL
    A0A8V0XQW9
    Conserved Domains (5) summary
    cd00060
    Location:418 → 500
    FHA; Forkhead associated domain (FHA); found in eukaryotic and prokaryotic proteins. Putative nuclear signalling domain. FHA domains may bind phosphothreonine, phosphoserine and sometimes phosphotyrosine. In eukaryotes, many FHA domain-containing proteins ...
    cd00992
    Location:1015 → 1098
    PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
    cd15471
    Location:612 → 940
    Myo5p-like_CBD_afadin; cargo binding domain of myosin 5-like of afadin
    cd01781
    Location:248 → 348
    RA2_Afadin; Ras-associating (RA) domain 2 found in Afadin
    cd01782
    Location:21 → 132
    RA1_Afadin; Ras-associating (RA) domain 1 found in Afadin

  6. XM_015284345.4 → XP_015139831.2  afadin isoform X2

    UniProtKB/TrEMBL
    A0A8V0XEE1, A0A8V0XL29
    Conserved Domains (6) summary
    cd00060
    Location:418 → 500
    FHA; Forkhead associated domain (FHA); found in eukaryotic and prokaryotic proteins. Putative nuclear signalling domain. FHA domains may bind phosphothreonine, phosphoserine and sometimes phosphotyrosine. In eukaryotes, many FHA domain-containing proteins ...
    cd00992
    Location:1015 → 1098
    PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
    cd15471
    Location:612 → 940
    Myo5p-like_CBD_afadin; cargo binding domain of myosin 5-like of afadin
    cd01781
    Location:248 → 348
    RA2_Afadin; Ras-associating (RA) domain 2 found in Afadin
    cd01782
    Location:21 → 132
    RA1_Afadin; Ras-associating (RA) domain 1 found in Afadin
    pfam17380
    Location:1535 → 1721
    DUF5401; Family of unknown function (DUF5401)

  7. XM_015284352.4 → XP_015139838.2  afadin isoform X11

    UniProtKB/TrEMBL
    A0A8V0XL29
    Related
    ENSGALP00010006494.1, ENSGALT00010011616.1
    Conserved Domains (6) summary
    cd00060
    Location:386 → 486
    FHA; Forkhead associated domain (FHA); found in eukaryotic and prokaryotic proteins. Putative nuclear signalling domain. FHA domains may bind phosphothreonine, phosphoserine and sometimes phosphotyrosine. In eukaryotes, many FHA domain-containing proteins ...
    cd00992
    Location:994 → 1077
    PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
    cd15471
    Location:598 → 919
    Myo5p-like_CBD_afadin; cargo binding domain of myosin 5-like of afadin
    cd01781
    Location:249 → 349
    RA2_Afadin; Ras-associating (RA) domain 2 found in Afadin
    cd01782
    Location:21 → 133
    RA1_Afadin; Ras-associating (RA) domain 1 found in Afadin
    pfam17380
    Location:1514 → 1700
    DUF5401; Family of unknown function (DUF5401)

  8. XM_040698601.2 → XP_040554535.1  afadin isoform X20

    UniProtKB/TrEMBL
    A0A8V0XEE1, A0A8V0XL29
    Conserved Domains (5) summary
    cd00060
    Location:386 → 486
    FHA; Forkhead associated domain (FHA); found in eukaryotic and prokaryotic proteins. Putative nuclear signalling domain. FHA domains may bind phosphothreonine, phosphoserine and sometimes phosphotyrosine. In eukaryotes, many FHA domain-containing proteins ...
    cd00992
    Location:1001 → 1084
    PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
    cd15471
    Location:598 → 926
    Myo5p-like_CBD_afadin; cargo binding domain of myosin 5-like of afadin
    cd01781
    Location:249 → 349
    RA2_Afadin; Ras-associating (RA) domain 2 found in Afadin
    cd01782
    Location:21 → 133
    RA1_Afadin; Ras-associating (RA) domain 1 found in Afadin

  9. XM_015284351.4 → XP_015139837.2  afadin isoform X8

    UniProtKB/TrEMBL
    A0A8V0XEE1, A0A8V0XL29
    Conserved Domains (6) summary
    cd00060
    Location:386 → 486
    FHA; Forkhead associated domain (FHA); found in eukaryotic and prokaryotic proteins. Putative nuclear signalling domain. FHA domains may bind phosphothreonine, phosphoserine and sometimes phosphotyrosine. In eukaryotes, many FHA domain-containing proteins ...
    cd00992
    Location:1001 → 1084
    PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
    cd15471
    Location:598 → 926
    Myo5p-like_CBD_afadin; cargo binding domain of myosin 5-like of afadin
    cd01781
    Location:249 → 349
    RA2_Afadin; Ras-associating (RA) domain 2 found in Afadin
    cd01782
    Location:21 → 133
    RA1_Afadin; Ras-associating (RA) domain 1 found in Afadin
    pfam17380
    Location:1521 → 1707
    DUF5401; Family of unknown function (DUF5401)

  10. XM_015284356.4 → XP_015139842.2  afadin isoform X18

    UniProtKB/TrEMBL
    A0A8V0XQW9
    Conserved Domains (5) summary
    cd00060
    Location:419 → 501
    FHA; Forkhead associated domain (FHA); found in eukaryotic and prokaryotic proteins. Putative nuclear signalling domain. FHA domains may bind phosphothreonine, phosphoserine and sometimes phosphotyrosine. In eukaryotes, many FHA domain-containing proteins ...
    cd00992
    Location:1009 → 1092
    PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
    cd15471
    Location:613 → 934
    Myo5p-like_CBD_afadin; cargo binding domain of myosin 5-like of afadin
    cd01781
    Location:249 → 349
    RA2_Afadin; Ras-associating (RA) domain 2 found in Afadin
    cd01782
    Location:21 → 133
    RA1_Afadin; Ras-associating (RA) domain 1 found in Afadin

  11. XM_015284348.4 → XP_015139834.2  afadin isoform X5

    UniProtKB/TrEMBL
    A0A8V0XL29
    Conserved Domains (6) summary
    cd00060
    Location:419 → 501
    FHA; Forkhead associated domain (FHA); found in eukaryotic and prokaryotic proteins. Putative nuclear signalling domain. FHA domains may bind phosphothreonine, phosphoserine and sometimes phosphotyrosine. In eukaryotes, many FHA domain-containing proteins ...
    cd00992
    Location:1009 → 1092
    PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
    cd15471
    Location:613 → 934
    Myo5p-like_CBD_afadin; cargo binding domain of myosin 5-like of afadin
    cd01781
    Location:249 → 349
    RA2_Afadin; Ras-associating (RA) domain 2 found in Afadin
    cd01782
    Location:21 → 133
    RA1_Afadin; Ras-associating (RA) domain 1 found in Afadin
    pfam17380
    Location:1529 → 1715
    DUF5401; Family of unknown function (DUF5401)

  12. XM_040698603.2 → XP_040554537.1  afadin isoform X25

    UniProtKB/TrEMBL
    A0A8V0XQW9
    Conserved Domains (6) summary
    cd00060
    Location:419 → 501
    FHA; Forkhead associated domain (FHA); found in eukaryotic and prokaryotic proteins. Putative nuclear signalling domain. FHA domains may bind phosphothreonine, phosphoserine and sometimes phosphotyrosine. In eukaryotes, many FHA domain-containing proteins ...
    cd00992
    Location:1016 → 1099
    PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
    cd15471
    Location:613 → 941
    Myo5p-like_CBD_afadin; cargo binding domain of myosin 5-like of afadin
    cd01781
    Location:249 → 349
    RA2_Afadin; Ras-associating (RA) domain 2 found in Afadin
    cd01782
    Location:21 → 133
    RA1_Afadin; Ras-associating (RA) domain 1 found in Afadin
    pfam17380
    Location:1489 → 1632
    DUF5401; Family of unknown function (DUF5401)

  13. XM_040698599.2 → XP_040554533.1  afadin isoform X16

    UniProtKB/TrEMBL
    A0A8V0XQW9
    Conserved Domains (5) summary
    cd00060
    Location:419 → 501
    FHA; Forkhead associated domain (FHA); found in eukaryotic and prokaryotic proteins. Putative nuclear signalling domain. FHA domains may bind phosphothreonine, phosphoserine and sometimes phosphotyrosine. In eukaryotes, many FHA domain-containing proteins ...
    cd00992
    Location:1016 → 1099
    PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
    cd15471
    Location:613 → 941
    Myo5p-like_CBD_afadin; cargo binding domain of myosin 5-like of afadin
    cd01781
    Location:249 → 349
    RA2_Afadin; Ras-associating (RA) domain 2 found in Afadin
    cd01782
    Location:21 → 133
    RA1_Afadin; Ras-associating (RA) domain 1 found in Afadin

  14. XM_040698595.2 → XP_040554529.1  afadin isoform X9

    UniProtKB/TrEMBL
    A0A8V0XEE1
    Related
    ENSGALP00010006497.1, ENSGALT00010011622.1
    Conserved Domains (5) summary
    cd00060
    Location:419 → 501
    FHA; Forkhead associated domain (FHA); found in eukaryotic and prokaryotic proteins. Putative nuclear signalling domain. FHA domains may bind phosphothreonine, phosphoserine and sometimes phosphotyrosine. In eukaryotes, many FHA domain-containing proteins ...
    cd00992
    Location:1016 → 1099
    PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
    cd15471
    Location:613 → 941
    Myo5p-like_CBD_afadin; cargo binding domain of myosin 5-like of afadin
    cd01781
    Location:249 → 349
    RA2_Afadin; Ras-associating (RA) domain 2 found in Afadin
    cd01782
    Location:21 → 133
    RA1_Afadin; Ras-associating (RA) domain 1 found in Afadin

  15. XM_015284347.4 → XP_015139833.2  afadin isoform X4

    UniProtKB/TrEMBL
    A0A8V0XEE1
    Conserved Domains (6) summary
    cd00060
    Location:419 → 501
    FHA; Forkhead associated domain (FHA); found in eukaryotic and prokaryotic proteins. Putative nuclear signalling domain. FHA domains may bind phosphothreonine, phosphoserine and sometimes phosphotyrosine. In eukaryotes, many FHA domain-containing proteins ...
    cd00992
    Location:1016 → 1099
    PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
    cd15471
    Location:613 → 941
    Myo5p-like_CBD_afadin; cargo binding domain of myosin 5-like of afadin
    cd01781
    Location:249 → 349
    RA2_Afadin; Ras-associating (RA) domain 2 found in Afadin
    cd01782
    Location:21 → 133
    RA1_Afadin; Ras-associating (RA) domain 1 found in Afadin
    pfam17380
    Location:1529 → 1715
    DUF5401; Family of unknown function (DUF5401)

  16. XM_040698602.2 → XP_040554536.1  afadin isoform X24

    UniProtKB/TrEMBL
    A0A8V0XQW9
    Conserved Domains (5) summary
    cd00060
    Location:419 → 501
    FHA; Forkhead associated domain (FHA); found in eukaryotic and prokaryotic proteins. Putative nuclear signalling domain. FHA domains may bind phosphothreonine, phosphoserine and sometimes phosphotyrosine. In eukaryotes, many FHA domain-containing proteins ...
    cd00992
    Location:1016 → 1099
    PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
    cd15471
    Location:613 → 941
    Myo5p-like_CBD_afadin; cargo binding domain of myosin 5-like of afadin
    cd01781
    Location:249 → 349
    RA2_Afadin; Ras-associating (RA) domain 2 found in Afadin
    cd01782
    Location:21 → 133
    RA1_Afadin; Ras-associating (RA) domain 1 found in Afadin

  17. XM_015284350.4 → XP_015139836.2  afadin isoform X7

    UniProtKB/TrEMBL
    A0A8V0XEE1, A0A8V0XL29
    Conserved Domains (5) summary
    cd00060
    Location:419 → 501
    FHA; Forkhead associated domain (FHA); found in eukaryotic and prokaryotic proteins. Putative nuclear signalling domain. FHA domains may bind phosphothreonine, phosphoserine and sometimes phosphotyrosine. In eukaryotes, many FHA domain-containing proteins ...
    cd00992
    Location:1016 → 1099
    PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
    cd15471
    Location:613 → 941
    Myo5p-like_CBD_afadin; cargo binding domain of myosin 5-like of afadin
    cd01781
    Location:249 → 349
    RA2_Afadin; Ras-associating (RA) domain 2 found in Afadin
    cd01782
    Location:21 → 133
    RA1_Afadin; Ras-associating (RA) domain 1 found in Afadin

  18. XM_015284358.4 → XP_015139844.2  afadin isoform X23

    UniProtKB/TrEMBL
    A0A8V0XQW9
    Conserved Domains (6) summary
    cd00060
    Location:419 → 501
    FHA; Forkhead associated domain (FHA); found in eukaryotic and prokaryotic proteins. Putative nuclear signalling domain. FHA domains may bind phosphothreonine, phosphoserine and sometimes phosphotyrosine. In eukaryotes, many FHA domain-containing proteins ...
    cd00992
    Location:1016 → 1099
    PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
    cd15471
    Location:613 → 941
    Myo5p-like_CBD_afadin; cargo binding domain of myosin 5-like of afadin
    cd01781
    Location:249 → 349
    RA2_Afadin; Ras-associating (RA) domain 2 found in Afadin
    cd01782
    Location:21 → 133
    RA1_Afadin; Ras-associating (RA) domain 1 found in Afadin
    pfam17380
    Location:1496 → 1639
    DUF5401; Family of unknown function (DUF5401)

  19. XM_040698597.2 → XP_040554531.1  afadin isoform X14

    UniProtKB/TrEMBL
    A0A8V0XQW9
    Conserved Domains (5) summary
    cd00060
    Location:419 → 501
    FHA; Forkhead associated domain (FHA); found in eukaryotic and prokaryotic proteins. Putative nuclear signalling domain. FHA domains may bind phosphothreonine, phosphoserine and sometimes phosphotyrosine. In eukaryotes, many FHA domain-containing proteins ...
    cd00992
    Location:1016 → 1099
    PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
    cd15471
    Location:613 → 941
    Myo5p-like_CBD_afadin; cargo binding domain of myosin 5-like of afadin
    cd01781
    Location:249 → 349
    RA2_Afadin; Ras-associating (RA) domain 2 found in Afadin
    cd01782
    Location:21 → 133
    RA1_Afadin; Ras-associating (RA) domain 1 found in Afadin

  20. XM_015284349.4 → XP_015139835.2  afadin isoform X6

    UniProtKB/TrEMBL
    A0A8V0XEE1, A0A8V0XL29
    Conserved Domains (5) summary
    cd00060
    Location:419 → 501
    FHA; Forkhead associated domain (FHA); found in eukaryotic and prokaryotic proteins. Putative nuclear signalling domain. FHA domains may bind phosphothreonine, phosphoserine and sometimes phosphotyrosine. In eukaryotes, many FHA domain-containing proteins ...
    cd00992
    Location:1016 → 1099
    PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
    cd15471
    Location:613 → 941
    Myo5p-like_CBD_afadin; cargo binding domain of myosin 5-like of afadin
    cd01781
    Location:249 → 349
    RA2_Afadin; Ras-associating (RA) domain 2 found in Afadin
    cd01782
    Location:21 → 133
    RA1_Afadin; Ras-associating (RA) domain 1 found in Afadin

  21. XM_046939019.1 → XP_046794975.1  afadin isoform X22

  22. XM_015284346.4 → XP_015139832.2  afadin isoform X3

    UniProtKB/TrEMBL
    A0A8V0XEE1, A0A8V0XL29
    Conserved Domains (5) summary
    cd00060
    Location:419 → 501
    FHA; Forkhead associated domain (FHA); found in eukaryotic and prokaryotic proteins. Putative nuclear signalling domain. FHA domains may bind phosphothreonine, phosphoserine and sometimes phosphotyrosine. In eukaryotes, many FHA domain-containing proteins ...
    cd00992
    Location:1016 → 1099
    PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
    cd15471
    Location:613 → 941
    Myo5p-like_CBD_afadin; cargo binding domain of myosin 5-like of afadin
    cd01781
    Location:249 → 349
    RA2_Afadin; Ras-associating (RA) domain 2 found in Afadin
    cd01782
    Location:21 → 133
    RA1_Afadin; Ras-associating (RA) domain 1 found in Afadin

  23. XM_015284357.4 → XP_015139843.2  afadin isoform X21

    UniProtKB/TrEMBL
    A0A8V0XQW9
    Conserved Domains (5) summary
    cd00060
    Location:419 → 501
    FHA; Forkhead associated domain (FHA); found in eukaryotic and prokaryotic proteins. Putative nuclear signalling domain. FHA domains may bind phosphothreonine, phosphoserine and sometimes phosphotyrosine. In eukaryotes, many FHA domain-containing proteins ...
    cd00992
    Location:1016 → 1099
    PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
    cd15471
    Location:613 → 941
    Myo5p-like_CBD_afadin; cargo binding domain of myosin 5-like of afadin
    cd01781
    Location:249 → 349
    RA2_Afadin; Ras-associating (RA) domain 2 found in Afadin
    cd01782
    Location:21 → 133
    RA1_Afadin; Ras-associating (RA) domain 1 found in Afadin

  24. XM_015284354.4 → XP_015139840.2  afadin isoform X13

    UniProtKB/TrEMBL
    A0A8V0XQW9
    Related
    ENSGALP00010006503.1, ENSGALT00010011632.1
    Conserved Domains (6) summary
    cd00060
    Location:419 → 501
    FHA; Forkhead associated domain (FHA); found in eukaryotic and prokaryotic proteins. Putative nuclear signalling domain. FHA domains may bind phosphothreonine, phosphoserine and sometimes phosphotyrosine. In eukaryotes, many FHA domain-containing proteins ...
    cd00992
    Location:1016 → 1099
    PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
    cd15471
    Location:613 → 941
    Myo5p-like_CBD_afadin; cargo binding domain of myosin 5-like of afadin
    cd01781
    Location:249 → 349
    RA2_Afadin; Ras-associating (RA) domain 2 found in Afadin
    cd01782
    Location:21 → 133
    RA1_Afadin; Ras-associating (RA) domain 1 found in Afadin
    pfam17380
    Location:1536 → 1722
    DUF5401; Family of unknown function (DUF5401)

  25. XM_015284344.4 → XP_015139830.2  afadin isoform X1

    UniProtKB/TrEMBL
    A0A8V0XEE1, A0A8V0XL29
    Conserved Domains (6) summary
    cd00060
    Location:419 → 501
    FHA; Forkhead associated domain (FHA); found in eukaryotic and prokaryotic proteins. Putative nuclear signalling domain. FHA domains may bind phosphothreonine, phosphoserine and sometimes phosphotyrosine. In eukaryotes, many FHA domain-containing proteins ...
    cd00992
    Location:1016 → 1099
    PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
    cd15471
    Location:613 → 941
    Myo5p-like_CBD_afadin; cargo binding domain of myosin 5-like of afadin
    cd01781
    Location:249 → 349
    RA2_Afadin; Ras-associating (RA) domain 2 found in Afadin
    cd01782
    Location:21 → 133
    RA1_Afadin; Ras-associating (RA) domain 1 found in Afadin
    pfam17380
    Location:1536 → 1722
    DUF5401; Family of unknown function (DUF5401)

  26. XM_040698596.2 → XP_040554530.1  afadin isoform X12

    UniProtKB/TrEMBL
    A0A8V0XEE1, A0A8V0XL29
    Conserved Domains (6) summary
    cd00060
    Location:376 → 458
    FHA; Forkhead associated domain (FHA); found in eukaryotic and prokaryotic proteins. Putative nuclear signalling domain. FHA domains may bind phosphothreonine, phosphoserine and sometimes phosphotyrosine. In eukaryotes, many FHA domain-containing proteins ...
    cd00992
    Location:973 → 1056
    PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
    cd15471
    Location:570 → 898
    Myo5p-like_CBD_afadin; cargo binding domain of myosin 5-like of afadin
    cd01781
    Location:206 → 306
    RA2_Afadin; Ras-associating (RA) domain 2 found in Afadin
    pfam17380
    Location:1493 → 1679
    DUF5401; Family of unknown function (DUF5401)
    cl28922
    Location:1 → 90
    Ubiquitin_like_fold; Beta-grasp ubiquitin-like fold

  27. XM_015284359.4 → XP_015139845.2  afadin isoform X26

    UniProtKB/TrEMBL
    A0A8V0XIG9
    Related
    ENSGALP00010006491.1, ENSGALT00010011606.1
    Conserved Domains (5) summary
    cd00060
    Location:419 → 501
    FHA; Forkhead associated domain (FHA); found in eukaryotic and prokaryotic proteins. Putative nuclear signalling domain. FHA domains may bind phosphothreonine, phosphoserine and sometimes phosphotyrosine. In eukaryotes, many FHA domain-containing proteins ...
    cd00992
    Location:1016 → 1099
    PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
    cd15471
    Location:613 → 941
    Myo5p-like_CBD_afadin; cargo binding domain of myosin 5-like of afadin
    cd01781
    Location:249 → 349
    RA2_Afadin; Ras-associating (RA) domain 2 found in Afadin
    cd01782
    Location:21 → 133
    RA1_Afadin; Ras-associating (RA) domain 1 found in Afadin

RNA

  1. XR_001465955.4 RNA Sequence

Alternate bGalGal1.pat.whiteleghornlayer.GRCg7w

Genomic

  1. NC_052575.1 Alternate bGalGal1.pat.whiteleghornlayer.GRCg7w

    Range
    41693640..41807840 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_040669077.2 → XP_040525011.1  afadin isoform X27

    UniProtKB/TrEMBL
    A0A8V0XQW9
    Conserved Domains (6) summary
    cd00060
    Location:385 → 485
    FHA; Forkhead associated domain (FHA); found in eukaryotic and prokaryotic proteins. Putative nuclear signalling domain. FHA domains may bind phosphothreonine, phosphoserine and sometimes phosphotyrosine. In eukaryotes, many FHA domain-containing proteins ...
    cd00992
    Location:993 → 1076
    PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
    cd15471
    Location:597 → 918
    Myo5p-like_CBD_afadin; cargo binding domain of myosin 5-like of afadin
    cd01781
    Location:248 → 348
    RA2_Afadin; Ras-associating (RA) domain 2 found in Afadin
    cd01782
    Location:21 → 132
    RA1_Afadin; Ras-associating (RA) domain 1 found in Afadin
    pfam17380
    Location:1473 → 1616
    DUF5401; Family of unknown function (DUF5401)

  2. XM_040669070.2 → XP_040525004.1  afadin isoform X19

    UniProtKB/TrEMBL
    A0A8V0XQW9
    Conserved Domains (5) summary
    cd00060
    Location:418 → 500
    FHA; Forkhead associated domain (FHA); found in eukaryotic and prokaryotic proteins. Putative nuclear signalling domain. FHA domains may bind phosphothreonine, phosphoserine and sometimes phosphotyrosine. In eukaryotes, many FHA domain-containing proteins ...
    cd00992
    Location:1008 → 1091
    PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
    cd15471
    Location:612 → 933
    Myo5p-like_CBD_afadin; cargo binding domain of myosin 5-like of afadin
    cd01781
    Location:248 → 348
    RA2_Afadin; Ras-associating (RA) domain 2 found in Afadin
    cd01782
    Location:21 → 132
    RA1_Afadin; Ras-associating (RA) domain 1 found in Afadin

  3. XM_040669061.2 → XP_040524995.1  afadin isoform X10

    UniProtKB/TrEMBL
    A0A8V0XL29
    Conserved Domains (5) summary
    cd00060
    Location:418 → 500
    FHA; Forkhead associated domain (FHA); found in eukaryotic and prokaryotic proteins. Putative nuclear signalling domain. FHA domains may bind phosphothreonine, phosphoserine and sometimes phosphotyrosine. In eukaryotes, many FHA domain-containing proteins ...
    cd00992
    Location:1008 → 1091
    PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
    cd15471
    Location:612 → 933
    Myo5p-like_CBD_afadin; cargo binding domain of myosin 5-like of afadin
    cd01781
    Location:248 → 348
    RA2_Afadin; Ras-associating (RA) domain 2 found in Afadin
    cd01782
    Location:21 → 132
    RA1_Afadin; Ras-associating (RA) domain 1 found in Afadin

  4. XM_040669068.2 → XP_040525002.1  afadin isoform X17

    UniProtKB/TrEMBL
    A0A8V0XQW9
    Conserved Domains (5) summary
    cd00060
    Location:418 → 500
    FHA; Forkhead associated domain (FHA); found in eukaryotic and prokaryotic proteins. Putative nuclear signalling domain. FHA domains may bind phosphothreonine, phosphoserine and sometimes phosphotyrosine. In eukaryotes, many FHA domain-containing proteins ...
    cd00992
    Location:1008 → 1091
    PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
    cd15471
    Location:612 → 933
    Myo5p-like_CBD_afadin; cargo binding domain of myosin 5-like of afadin
    cd01781
    Location:248 → 348
    RA2_Afadin; Ras-associating (RA) domain 2 found in Afadin
    cd01782
    Location:21 → 132
    RA1_Afadin; Ras-associating (RA) domain 1 found in Afadin

  5. XM_040669066.2 → XP_040525000.1  afadin isoform X15

    UniProtKB/TrEMBL
    A0A8V0XQW9
    Conserved Domains (5) summary
    cd00060
    Location:418 → 500
    FHA; Forkhead associated domain (FHA); found in eukaryotic and prokaryotic proteins. Putative nuclear signalling domain. FHA domains may bind phosphothreonine, phosphoserine and sometimes phosphotyrosine. In eukaryotes, many FHA domain-containing proteins ...
    cd00992
    Location:1015 → 1098
    PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
    cd15471
    Location:612 → 940
    Myo5p-like_CBD_afadin; cargo binding domain of myosin 5-like of afadin
    cd01781
    Location:248 → 348
    RA2_Afadin; Ras-associating (RA) domain 2 found in Afadin
    cd01782
    Location:21 → 132
    RA1_Afadin; Ras-associating (RA) domain 1 found in Afadin

  6. XM_040669053.2 → XP_040524987.1  afadin isoform X2

    UniProtKB/TrEMBL
    A0A8V0XEE1, A0A8V0XL29
    Conserved Domains (6) summary
    cd00060
    Location:418 → 500
    FHA; Forkhead associated domain (FHA); found in eukaryotic and prokaryotic proteins. Putative nuclear signalling domain. FHA domains may bind phosphothreonine, phosphoserine and sometimes phosphotyrosine. In eukaryotes, many FHA domain-containing proteins ...
    cd00992
    Location:1015 → 1098
    PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
    cd15471
    Location:612 → 940
    Myo5p-like_CBD_afadin; cargo binding domain of myosin 5-like of afadin
    cd01781
    Location:248 → 348
    RA2_Afadin; Ras-associating (RA) domain 2 found in Afadin
    cd01782
    Location:21 → 132
    RA1_Afadin; Ras-associating (RA) domain 1 found in Afadin
    pfam17380
    Location:1535 → 1721
    DUF5401; Family of unknown function (DUF5401)

  7. XM_040669062.2 → XP_040524996.1  afadin isoform X11

    UniProtKB/TrEMBL
    A0A8V0XL29
    Conserved Domains (6) summary
    cd00060
    Location:386 → 486
    FHA; Forkhead associated domain (FHA); found in eukaryotic and prokaryotic proteins. Putative nuclear signalling domain. FHA domains may bind phosphothreonine, phosphoserine and sometimes phosphotyrosine. In eukaryotes, many FHA domain-containing proteins ...
    cd00992
    Location:994 → 1077
    PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
    cd15471
    Location:598 → 919
    Myo5p-like_CBD_afadin; cargo binding domain of myosin 5-like of afadin
    cd01781
    Location:249 → 349
    RA2_Afadin; Ras-associating (RA) domain 2 found in Afadin
    cd01782
    Location:21 → 133
    RA1_Afadin; Ras-associating (RA) domain 1 found in Afadin
    pfam17380
    Location:1514 → 1700
    DUF5401; Family of unknown function (DUF5401)

  8. XM_040669071.2 → XP_040525005.1  afadin isoform X20

    UniProtKB/TrEMBL
    A0A8V0XEE1, A0A8V0XL29
    Conserved Domains (5) summary
    cd00060
    Location:386 → 486
    FHA; Forkhead associated domain (FHA); found in eukaryotic and prokaryotic proteins. Putative nuclear signalling domain. FHA domains may bind phosphothreonine, phosphoserine and sometimes phosphotyrosine. In eukaryotes, many FHA domain-containing proteins ...
    cd00992
    Location:1001 → 1084
    PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
    cd15471
    Location:598 → 926
    Myo5p-like_CBD_afadin; cargo binding domain of myosin 5-like of afadin
    cd01781
    Location:249 → 349
    RA2_Afadin; Ras-associating (RA) domain 2 found in Afadin
    cd01782
    Location:21 → 133
    RA1_Afadin; Ras-associating (RA) domain 1 found in Afadin

  9. XM_040669059.2 → XP_040524993.1  afadin isoform X8

    UniProtKB/TrEMBL
    A0A8V0XEE1, A0A8V0XL29
    Conserved Domains (6) summary
    cd00060
    Location:386 → 486
    FHA; Forkhead associated domain (FHA); found in eukaryotic and prokaryotic proteins. Putative nuclear signalling domain. FHA domains may bind phosphothreonine, phosphoserine and sometimes phosphotyrosine. In eukaryotes, many FHA domain-containing proteins ...
    cd00992
    Location:1001 → 1084
    PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
    cd15471
    Location:598 → 926
    Myo5p-like_CBD_afadin; cargo binding domain of myosin 5-like of afadin
    cd01781
    Location:249 → 349
    RA2_Afadin; Ras-associating (RA) domain 2 found in Afadin
    cd01782
    Location:21 → 133
    RA1_Afadin; Ras-associating (RA) domain 1 found in Afadin
    pfam17380
    Location:1521 → 1707
    DUF5401; Family of unknown function (DUF5401)

  10. XM_040669069.2 → XP_040525003.1  afadin isoform X18

    UniProtKB/TrEMBL
    A0A8V0XQW9
    Conserved Domains (5) summary
    cd00060
    Location:419 → 501
    FHA; Forkhead associated domain (FHA); found in eukaryotic and prokaryotic proteins. Putative nuclear signalling domain. FHA domains may bind phosphothreonine, phosphoserine and sometimes phosphotyrosine. In eukaryotes, many FHA domain-containing proteins ...
    cd00992
    Location:1009 → 1092
    PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
    cd15471
    Location:613 → 934
    Myo5p-like_CBD_afadin; cargo binding domain of myosin 5-like of afadin
    cd01781
    Location:249 → 349
    RA2_Afadin; Ras-associating (RA) domain 2 found in Afadin
    cd01782
    Location:21 → 133
    RA1_Afadin; Ras-associating (RA) domain 1 found in Afadin

  11. XM_040669056.2 → XP_040524990.1  afadin isoform X5

    UniProtKB/TrEMBL
    A0A8V0XL29
    Conserved Domains (6) summary
    cd00060
    Location:419 → 501
    FHA; Forkhead associated domain (FHA); found in eukaryotic and prokaryotic proteins. Putative nuclear signalling domain. FHA domains may bind phosphothreonine, phosphoserine and sometimes phosphotyrosine. In eukaryotes, many FHA domain-containing proteins ...
    cd00992
    Location:1009 → 1092
    PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
    cd15471
    Location:613 → 934
    Myo5p-like_CBD_afadin; cargo binding domain of myosin 5-like of afadin
    cd01781
    Location:249 → 349
    RA2_Afadin; Ras-associating (RA) domain 2 found in Afadin
    cd01782
    Location:21 → 133
    RA1_Afadin; Ras-associating (RA) domain 1 found in Afadin
    pfam17380
    Location:1529 → 1715
    DUF5401; Family of unknown function (DUF5401)

  12. XM_040669075.2 → XP_040525009.1  afadin isoform X25

    UniProtKB/TrEMBL
    A0A8V0XQW9
    Conserved Domains (6) summary
    cd00060
    Location:419 → 501
    FHA; Forkhead associated domain (FHA); found in eukaryotic and prokaryotic proteins. Putative nuclear signalling domain. FHA domains may bind phosphothreonine, phosphoserine and sometimes phosphotyrosine. In eukaryotes, many FHA domain-containing proteins ...
    cd00992
    Location:1016 → 1099
    PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
    cd15471
    Location:613 → 941
    Myo5p-like_CBD_afadin; cargo binding domain of myosin 5-like of afadin
    cd01781
    Location:249 → 349
    RA2_Afadin; Ras-associating (RA) domain 2 found in Afadin
    cd01782
    Location:21 → 133
    RA1_Afadin; Ras-associating (RA) domain 1 found in Afadin
    pfam17380
    Location:1489 → 1632
    DUF5401; Family of unknown function (DUF5401)

  13. XM_040669067.2 → XP_040525001.1  afadin isoform X16

    UniProtKB/TrEMBL
    A0A8V0XQW9
    Conserved Domains (5) summary
    cd00060
    Location:419 → 501
    FHA; Forkhead associated domain (FHA); found in eukaryotic and prokaryotic proteins. Putative nuclear signalling domain. FHA domains may bind phosphothreonine, phosphoserine and sometimes phosphotyrosine. In eukaryotes, many FHA domain-containing proteins ...
    cd00992
    Location:1016 → 1099
    PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
    cd15471
    Location:613 → 941
    Myo5p-like_CBD_afadin; cargo binding domain of myosin 5-like of afadin
    cd01781
    Location:249 → 349
    RA2_Afadin; Ras-associating (RA) domain 2 found in Afadin
    cd01782
    Location:21 → 133
    RA1_Afadin; Ras-associating (RA) domain 1 found in Afadin

  14. XM_040669060.2 → XP_040524994.1  afadin isoform X9

    UniProtKB/TrEMBL
    A0A8V0XEE1
    Conserved Domains (5) summary
    cd00060
    Location:419 → 501
    FHA; Forkhead associated domain (FHA); found in eukaryotic and prokaryotic proteins. Putative nuclear signalling domain. FHA domains may bind phosphothreonine, phosphoserine and sometimes phosphotyrosine. In eukaryotes, many FHA domain-containing proteins ...
    cd00992
    Location:1016 → 1099
    PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
    cd15471
    Location:613 → 941
    Myo5p-like_CBD_afadin; cargo binding domain of myosin 5-like of afadin
    cd01781
    Location:249 → 349
    RA2_Afadin; Ras-associating (RA) domain 2 found in Afadin
    cd01782
    Location:21 → 133
    RA1_Afadin; Ras-associating (RA) domain 1 found in Afadin

  15. XM_040669055.2 → XP_040524989.1  afadin isoform X4

    UniProtKB/TrEMBL
    A0A8V0XEE1
    Conserved Domains (6) summary
    cd00060
    Location:419 → 501
    FHA; Forkhead associated domain (FHA); found in eukaryotic and prokaryotic proteins. Putative nuclear signalling domain. FHA domains may bind phosphothreonine, phosphoserine and sometimes phosphotyrosine. In eukaryotes, many FHA domain-containing proteins ...
    cd00992
    Location:1016 → 1099
    PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
    cd15471
    Location:613 → 941
    Myo5p-like_CBD_afadin; cargo binding domain of myosin 5-like of afadin
    cd01781
    Location:249 → 349
    RA2_Afadin; Ras-associating (RA) domain 2 found in Afadin
    cd01782
    Location:21 → 133
    RA1_Afadin; Ras-associating (RA) domain 1 found in Afadin
    pfam17380
    Location:1529 → 1715
    DUF5401; Family of unknown function (DUF5401)

  16. XM_040669074.2 → XP_040525008.1  afadin isoform X24

    UniProtKB/TrEMBL
    A0A8V0XQW9
    Conserved Domains (5) summary
    cd00060
    Location:419 → 501
    FHA; Forkhead associated domain (FHA); found in eukaryotic and prokaryotic proteins. Putative nuclear signalling domain. FHA domains may bind phosphothreonine, phosphoserine and sometimes phosphotyrosine. In eukaryotes, many FHA domain-containing proteins ...
    cd00992
    Location:1016 → 1099
    PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
    cd15471
    Location:613 → 941
    Myo5p-like_CBD_afadin; cargo binding domain of myosin 5-like of afadin
    cd01781
    Location:249 → 349
    RA2_Afadin; Ras-associating (RA) domain 2 found in Afadin
    cd01782
    Location:21 → 133
    RA1_Afadin; Ras-associating (RA) domain 1 found in Afadin

  17. XM_040669058.2 → XP_040524992.1  afadin isoform X7

    UniProtKB/TrEMBL
    A0A8V0XEE1, A0A8V0XL29
    Conserved Domains (5) summary
    cd00060
    Location:419 → 501
    FHA; Forkhead associated domain (FHA); found in eukaryotic and prokaryotic proteins. Putative nuclear signalling domain. FHA domains may bind phosphothreonine, phosphoserine and sometimes phosphotyrosine. In eukaryotes, many FHA domain-containing proteins ...
    cd00992
    Location:1016 → 1099
    PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
    cd15471
    Location:613 → 941
    Myo5p-like_CBD_afadin; cargo binding domain of myosin 5-like of afadin
    cd01781
    Location:249 → 349
    RA2_Afadin; Ras-associating (RA) domain 2 found in Afadin
    cd01782
    Location:21 → 133
    RA1_Afadin; Ras-associating (RA) domain 1 found in Afadin

  18. XM_040669073.2 → XP_040525007.1  afadin isoform X23

    UniProtKB/TrEMBL
    A0A8V0XQW9
    Conserved Domains (6) summary
    cd00060
    Location:419 → 501
    FHA; Forkhead associated domain (FHA); found in eukaryotic and prokaryotic proteins. Putative nuclear signalling domain. FHA domains may bind phosphothreonine, phosphoserine and sometimes phosphotyrosine. In eukaryotes, many FHA domain-containing proteins ...
    cd00992
    Location:1016 → 1099
    PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
    cd15471
    Location:613 → 941
    Myo5p-like_CBD_afadin; cargo binding domain of myosin 5-like of afadin
    cd01781
    Location:249 → 349
    RA2_Afadin; Ras-associating (RA) domain 2 found in Afadin
    cd01782
    Location:21 → 133
    RA1_Afadin; Ras-associating (RA) domain 1 found in Afadin
    pfam17380
    Location:1496 → 1639
    DUF5401; Family of unknown function (DUF5401)

  19. XM_040669065.2 → XP_040524999.1  afadin isoform X14

    UniProtKB/TrEMBL
    A0A8V0XQW9
    Conserved Domains (5) summary
    cd00060
    Location:419 → 501
    FHA; Forkhead associated domain (FHA); found in eukaryotic and prokaryotic proteins. Putative nuclear signalling domain. FHA domains may bind phosphothreonine, phosphoserine and sometimes phosphotyrosine. In eukaryotes, many FHA domain-containing proteins ...
    cd00992
    Location:1016 → 1099
    PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
    cd15471
    Location:613 → 941
    Myo5p-like_CBD_afadin; cargo binding domain of myosin 5-like of afadin
    cd01781
    Location:249 → 349
    RA2_Afadin; Ras-associating (RA) domain 2 found in Afadin
    cd01782
    Location:21 → 133
    RA1_Afadin; Ras-associating (RA) domain 1 found in Afadin

  20. XM_040669057.2 → XP_040524991.1  afadin isoform X6

    UniProtKB/TrEMBL
    A0A8V0XEE1, A0A8V0XL29
    Conserved Domains (5) summary
    cd00060
    Location:419 → 501
    FHA; Forkhead associated domain (FHA); found in eukaryotic and prokaryotic proteins. Putative nuclear signalling domain. FHA domains may bind phosphothreonine, phosphoserine and sometimes phosphotyrosine. In eukaryotes, many FHA domain-containing proteins ...
    cd00992
    Location:1016 → 1099
    PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
    cd15471
    Location:613 → 941
    Myo5p-like_CBD_afadin; cargo binding domain of myosin 5-like of afadin
    cd01781
    Location:249 → 349
    RA2_Afadin; Ras-associating (RA) domain 2 found in Afadin
    cd01782
    Location:21 → 133
    RA1_Afadin; Ras-associating (RA) domain 1 found in Afadin

  21. XM_046914418.1 → XP_046770374.1  afadin isoform X22

  22. XM_040669054.2 → XP_040524988.1  afadin isoform X3

    UniProtKB/TrEMBL
    A0A8V0XEE1, A0A8V0XL29
    Conserved Domains (5) summary
    cd00060
    Location:419 → 501
    FHA; Forkhead associated domain (FHA); found in eukaryotic and prokaryotic proteins. Putative nuclear signalling domain. FHA domains may bind phosphothreonine, phosphoserine and sometimes phosphotyrosine. In eukaryotes, many FHA domain-containing proteins ...
    cd00992
    Location:1016 → 1099
    PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
    cd15471
    Location:613 → 941
    Myo5p-like_CBD_afadin; cargo binding domain of myosin 5-like of afadin
    cd01781
    Location:249 → 349
    RA2_Afadin; Ras-associating (RA) domain 2 found in Afadin
    cd01782
    Location:21 → 133
    RA1_Afadin; Ras-associating (RA) domain 1 found in Afadin

  23. XM_040669072.2 → XP_040525006.1  afadin isoform X21

    UniProtKB/TrEMBL
    A0A8V0XQW9
    Conserved Domains (5) summary
    cd00060
    Location:419 → 501
    FHA; Forkhead associated domain (FHA); found in eukaryotic and prokaryotic proteins. Putative nuclear signalling domain. FHA domains may bind phosphothreonine, phosphoserine and sometimes phosphotyrosine. In eukaryotes, many FHA domain-containing proteins ...
    cd00992
    Location:1016 → 1099
    PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
    cd15471
    Location:613 → 941
    Myo5p-like_CBD_afadin; cargo binding domain of myosin 5-like of afadin
    cd01781
    Location:249 → 349
    RA2_Afadin; Ras-associating (RA) domain 2 found in Afadin
    cd01782
    Location:21 → 133
    RA1_Afadin; Ras-associating (RA) domain 1 found in Afadin

  24. XM_040669064.2 → XP_040524998.1  afadin isoform X13

    UniProtKB/TrEMBL
    A0A8V0XQW9
    Conserved Domains (6) summary
    cd00060
    Location:419 → 501
    FHA; Forkhead associated domain (FHA); found in eukaryotic and prokaryotic proteins. Putative nuclear signalling domain. FHA domains may bind phosphothreonine, phosphoserine and sometimes phosphotyrosine. In eukaryotes, many FHA domain-containing proteins ...
    cd00992
    Location:1016 → 1099
    PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
    cd15471
    Location:613 → 941
    Myo5p-like_CBD_afadin; cargo binding domain of myosin 5-like of afadin
    cd01781
    Location:249 → 349
    RA2_Afadin; Ras-associating (RA) domain 2 found in Afadin
    cd01782
    Location:21 → 133
    RA1_Afadin; Ras-associating (RA) domain 1 found in Afadin
    pfam17380
    Location:1536 → 1722
    DUF5401; Family of unknown function (DUF5401)

  25. XM_040669052.2 → XP_040524986.1  afadin isoform X1

    UniProtKB/TrEMBL
    A0A8V0XEE1, A0A8V0XL29
    Conserved Domains (6) summary
    cd00060
    Location:419 → 501
    FHA; Forkhead associated domain (FHA); found in eukaryotic and prokaryotic proteins. Putative nuclear signalling domain. FHA domains may bind phosphothreonine, phosphoserine and sometimes phosphotyrosine. In eukaryotes, many FHA domain-containing proteins ...
    cd00992
    Location:1016 → 1099
    PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
    cd15471
    Location:613 → 941
    Myo5p-like_CBD_afadin; cargo binding domain of myosin 5-like of afadin
    cd01781
    Location:249 → 349
    RA2_Afadin; Ras-associating (RA) domain 2 found in Afadin
    cd01782
    Location:21 → 133
    RA1_Afadin; Ras-associating (RA) domain 1 found in Afadin
    pfam17380
    Location:1536 → 1722
    DUF5401; Family of unknown function (DUF5401)

  26. XM_040669063.2 → XP_040524997.1  afadin isoform X12

    UniProtKB/TrEMBL
    A0A8V0XEE1, A0A8V0XL29
    Conserved Domains (6) summary
    cd00060
    Location:376 → 458
    FHA; Forkhead associated domain (FHA); found in eukaryotic and prokaryotic proteins. Putative nuclear signalling domain. FHA domains may bind phosphothreonine, phosphoserine and sometimes phosphotyrosine. In eukaryotes, many FHA domain-containing proteins ...
    cd00992
    Location:973 → 1056
    PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
    cd15471
    Location:570 → 898
    Myo5p-like_CBD_afadin; cargo binding domain of myosin 5-like of afadin
    cd01781
    Location:206 → 306
    RA2_Afadin; Ras-associating (RA) domain 2 found in Afadin
    pfam17380
    Location:1493 → 1679
    DUF5401; Family of unknown function (DUF5401)
    cl28922
    Location:1 → 90
    Ubiquitin_like_fold; Beta-grasp ubiquitin-like fold

  27. XM_040669076.2 → XP_040525010.1  afadin isoform X26

    UniProtKB/TrEMBL
    A0A8V0XIG9
    Conserved Domains (5) summary
    cd00060
    Location:419 → 501
    FHA; Forkhead associated domain (FHA); found in eukaryotic and prokaryotic proteins. Putative nuclear signalling domain. FHA domains may bind phosphothreonine, phosphoserine and sometimes phosphotyrosine. In eukaryotes, many FHA domain-containing proteins ...
    cd00992
    Location:1016 → 1099
    PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
    cd15471
    Location:613 → 941
    Myo5p-like_CBD_afadin; cargo binding domain of myosin 5-like of afadin
    cd01781
    Location:249 → 349
    RA2_Afadin; Ras-associating (RA) domain 2 found in Afadin
    cd01782
    Location:21 → 133
    RA1_Afadin; Ras-associating (RA) domain 1 found in Afadin

RNA

  1. XR_005848895.2 RNA Sequence

Nucleotide Protein Strain
Heading Accession and Version

Gene LinkOut

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