SSPO SCO-spondin [Gallus gallus (chicken)] - Gene

Summary

Symbol: SSPOprovided by CGNC
Full Name: SCO-spondinprovided by CGNC
Primary source: CGNC:51238
See related: Ensembl:ENSGALG00010027228
Gene type: protein coding
RefSeq status: PROVISIONAL
Organism: Gallus gallus
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda; Coelurosauria; Aves; Neognathae; Galloanserae; Galliformes; Phasianidae; Phasianinae; Gallus
NEW: Try the new Gene table
Try the new Transcript table

Genomic context

Location:: chromosome: 2

Exon count:: 106

Annotation release	Status	Assembly	Chr	Location
106	current	bGalGal1.mat.broiler.GRCg7b (GCF_016699485.2)	2	NC_052533.1 (456244..492778)
106	current	bGalGal1.pat.whiteleghornlayer.GRCg7w (GCF_016700215.2)	2	NC_052574.1 (455419..492229)

Chromosome 2 - NC_052533.1 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

Go to the top of the page Help

Go to reference sequence details

Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

Bibliography

Go to the top of the page Help

GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Results suggest that SCO-spondin has a role in the development of the PC through its interaction with integrin beta1.
Title: Polarized expression of integrin beta1 in diencephalic roof plate during chick development, a possible receptor for SCO-spondin.

Submit: New GeneRIF Correction

General gene information

Go to the top of the page Help

Gene Ontology Provided by RefSeq

Function	Evidence Code	Pubs
enables protein binding	IEA Inferred from Electronic Annotation more info	PubMed

Component	Evidence Code	Pubs
located_in extracellular matrix	IEA Inferred from Electronic Annotation more info	PubMed
located_in extracellular space	IEA Inferred from Electronic Annotation more info	PubMed

General protein information

Go to the top of the page Help

Preferred Names: SCO-spondin

Names: SCO-spondin homolog (Bos taurus); subcommissural organ spondin

NCBI Reference Sequences (RefSeq)

Go to the top of the page Help

NEW Try the new Transcript table

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

NM_001006351.3 → NP_001006351.3 SCO-spondin precursor

Status: PROVISIONAL

Source sequence(s)

JAENSK010000035

UniProtKB/TrEMBL

A0A8V1A327

Related

ENSGALP00010040288.1, ENSGALT00010066022.1

Conserved Domains (9) summary

smart00192
Location:1570 → 1602

LDLa; Low-density lipoprotein receptor domain class A

smart00209
Location:2648 → 2699

TSP1; Thrombospondin type 1 repeats

smart00216
Location:1004 → 1163

VWD; von Willebrand factor (vWF) type D domain

smart00832
Location:752 → 820

C8; This domain contains 8 conserved cysteine residues

cd00057
Location:2179 → 2324

FA58C; Coagulation factor 5/8 C-terminal domain, discoidin domain; Cell surface-attached carbohydrate-binding domain, present in eukaryotes and assumed to have horizontally transferred to eubacterial genomes.

cd00112
Location:1632 → 1666

LDLa; Low Density Lipoprotein Receptor Class A domain, a cysteine-rich repeat that plays a central role in mammalian cholesterol metabolism; the receptor protein binds LDL and transports it into cells by endocytosis; 7 successive cysteine-rich repeats of about ...

PTZ00441
Location:3134 → 3182

PTZ00441; sporozoite surface protein 2 (SSP2); Provisional

cl17735
Location:5109 → 5164

VWC; von Willebrand factor type C domain

cl15278
Location:3972 → 4024

TSP_1; Thrombospondin type 1 domain