CXCL2 chemokine (C-X-C motif) ligand 2 [Sus scrofa (pig)] - Gene

Summary

Gene symbol: CXCL2
Gene description: chemokine (C-X-C motif) ligand 2
See related: Ensembl:ENSSSCG00000008959
Gene type: protein coding
RefSeq status: PROVISIONAL
Organism: Sus scrofa
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Artiodactyla; Suina; Suidae; Sus
Also known as: GRO2; GROB; MIP2; MIP2A; SCYB2
Expression: Broad expression in subcutaneous adipose (RPKM 11.6), lung (RPKM 9.2) and 7 other tissues See more
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Genomic context

Location:: chromosome: 8

Exon count:: 4

Annotation release	Status	Assembly	Chr	Location
106	current	Sscrofa11.1 (GCF_000003025.6)	8	NC_010450.4 (70157253..70159145)
105	previous assembly	Sscrofa10.2 (GCF_000003025.5)	8	NC_010450.3 (74310094..74311988)

Chromosome 8 - NC_010450.4 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

Expression

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See details

Project title: Transcriptome data used for gene annotation
Description: Nine kinds of tissues and a mixture of multiple tissues were sequenced for genome annotation
BioProject: PRJNA311523
Publication: PMID 27646534
Analysis date: Thu Dec 14 17:10:49 2017

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

reports transmural and perivascular expression patterns of chemokines CCL2 and CXCL2 and of chemokine receptors CCR2, CCR5, and CXCR4 following coronary angioplasty
Title: Sequential patterns of chemokine- and chemokine receptor-synthesis following vessel wall injury in porcine coronary arteries.

Submit: New GeneRIF Correction

General gene information

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Gene Ontology Provided by RefSeq

Function	Evidence Code	Pubs
enables CXCR chemokine receptor binding	IEA Inferred from Electronic Annotation more info	PubMed
enables chemokine activity	IEA Inferred from Electronic Annotation more info	PubMed

Process	Evidence Code	Pubs
involved_in antimicrobial humoral immune response mediated by antimicrobial peptide	IEA Inferred from Electronic Annotation more info	PubMed
involved_in cellular response to lipopolysaccharide	IEA Inferred from Electronic Annotation more info	PubMed
involved_in chemokine-mediated signaling pathway	IEA Inferred from Electronic Annotation more info	PubMed
involved_in inflammatory response	IEA Inferred from Electronic Annotation more info	PubMed
involved_in neutrophil chemotaxis	IEA Inferred from Electronic Annotation more info	PubMed

Component	Evidence Code	Pubs
located_in extracellular region	IEA Inferred from Electronic Annotation more info	PubMed
located_in extracellular space	IEA Inferred from Electronic Annotation more info	PubMed

General protein information

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Preferred Names: C-X-C motif chemokine 2

Names: chemokine ligand 2

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

NM_001001861.2 → NP_001001861.1 C-X-C motif chemokine 2 precursor

See identical proteins and their annotated locations for NP_001001861.1

Status: PROVISIONAL

Source sequence(s)

AY577905

UniProtKB/TrEMBL

A0A4X1T3L2, A0A4X1T4W1, A0A8D0WNB6, F1RUK7, Q6PUD4, Q6PUJ1

Related

ENSSSCP00000042681.2, ENSSSCT00000040395.3

Conserved Domains (1) summary

cd00273
Location:40 → 102

Chemokine_CXC; Chemokine_CXC: 1 of 4 subgroup designations based on the arrangement of the two N-terminal cysteine residues; includes a number of secreted growth factors and interferons involved in mitogenic, chemotactic, and inflammatory activity; many members ...