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mafgb v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog Gb [ Danio rerio (zebrafish) ]

Gene ID: 405877, updated on 27-Mar-2024

Summary

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Official Symbol
mafgbprovided by ZNC
Official Full Name
v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog Gbprovided by ZNC
Primary source
ZFIN:ZDB-GENE-040426-2403
See related
Ensembl:ENSDARG00000100097 AllianceGenome:ZFIN:ZDB-GENE-040426-2403
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Danio rerio
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
Also known as
mafg2; zgc:85896
Summary
Enables protein heterodimerization activity. Contributes to DNA binding activity and DNA-binding transcription factor activity. Acts upstream of or within positive regulation of transcription, DNA-templated. Part of transcription regulator complex. Orthologous to human MAFG (MAF bZIP transcription factor G). [provided by Alliance of Genome Resources, Apr 2022]
Orthologs
all
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Genomic context

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Location:
chromosome: 11
Exon count:
4
Annotation release Status Assembly Chr Location
106 current GRCz11 (GCF_000002035.6) 11 NC_007122.7 (45299285..45328509)
105 previous assembly GRCz10 (GCF_000002035.5) 11 NC_007122.6 (44921767..44951272)

Chromosome 11 - NC_007122.7Genomic Context describing neighboring genes Neighboring gene ASPSCR1 tether for SLC2A4, UBX domain containing Neighboring gene pyrroline-5-carboxylate reductase 1b Neighboring gene centriolar coiled-coil protein 110 Neighboring gene trafficking protein particle complex subunit 10

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • BioProject: PRJEB1986
  • Analysis date: Fri Dec 8 19:48:10 2017

Bibliography

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Related articles in PubMed

  1. MafT, a new member of the small Maf protein family in zebrafish. Takagi Y, et al. Biochem Biophys Res Commun, 2004 Jul 16. PMID 15207702
  2. H(2)O(2)/DEM-Promoted Maft Promoter Demethylation Drives Nrf2/ARE Activation in Zebrafish. Chen C, et al. Life (Basel), 2022 Sep 15. PMID 36143473, Free PMC Article
  3. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article
  4. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Markers

Homology

Clone Names

  • MGC85896

Gene Ontology Provided by ZFIN

Function Evidence Code Pubs
enables DNA binding IEA
Inferred from Electronic Annotation
more info
  
contributes_to DNA binding IPI
Inferred from Physical Interaction
more info
 PubMed 
enables DNA-binding transcription factor activity IEA
Inferred from Electronic Annotation
more info
  
contributes_to DNA-binding transcription factor activity IGI
Inferred from Genetic Interaction
more info
 PubMed 
enables DNA-binding transcription factor activity, RNA polymerase II-specific IBA
Inferred from Biological aspect of Ancestor
more info
  
enables RNA polymerase II cis-regulatory region sequence-specific DNA binding IBA
Inferred from Biological aspect of Ancestor
more info
  
enables protein heterodimerization activity IPI
Inferred from Physical Interaction
more info
 PubMed 
Process Evidence Code Pubs
acts_upstream_of_or_within positive regulation of DNA-templated transcription IGI
Inferred from Genetic Interaction
more info
 PubMed 
acts_upstream_of_or_within regulation of DNA-templated transcription IEA
Inferred from Electronic Annotation
more info
  
involved_in regulation of epidermal cell differentiation IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in regulation of transcription by RNA polymerase II IBA
Inferred from Biological aspect of Ancestor
more info
  
Component Evidence Code Pubs
is_active_in nucleus IBA
Inferred from Biological aspect of Ancestor
more info
  
located_in nucleus IEA
Inferred from Electronic Annotation
more info
  
part_of transcription regulator complex IDA
Inferred from Direct Assay
more info
 PubMed 

General protein information

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Preferred Names
v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog Gb
Names
v-maf musculoaponeurotic fibrosarcoma oncogene homolog g, 2

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_212941.1 → NP_998106.1  v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog Gb

    See identical proteins and their annotated locations for NP_998106.1

    Status: PROVISIONAL

    Source sequence(s)
    BC067680
    UniProtKB/TrEMBL
    A0A140LG44, A0A2R8QBH0, Q6NW89
    Related
    ENSDARP00000138294.1, ENSDART00000172238.2
    Conserved Domains (1) summary
    cd14717
    Location:46 → 115
    bZIP_Maf_small; Basic leucine zipper (bZIP) domain of small musculoaponeurotic fibrosarcoma (Maf) proteins: a DNA-binding and dimerization domain

RefSeqs of Annotated Genomes: Danio rerio Annotation Release 106 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCz11 Primary Assembly

Genomic

  1. NC_007122.7 Reference GRCz11 Primary Assembly

    Range
    45299285..45328509
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_005169422.4 → XP_005169479.1  v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog Gb isoform X1

    UniProtKB/TrEMBL
    A0A8M2BGQ2
    Conserved Domains (1) summary
    cd14717
    Location:109 → 178
    bZIP_Maf_small; Basic leucine zipper (bZIP) domain of small musculoaponeurotic fibrosarcoma (Maf) proteins: a DNA-binding and dimerization domain

  2. XM_009306341.3 → XP_009304616.1  v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog Gb isoform X2

    See identical proteins and their annotated locations for XP_009304616.1

    UniProtKB/TrEMBL
    A0A140LG44, A0A2R8QBH0, Q6NW89
    Related
    ENSDARP00000142222.1, ENSDART00000172999.2
    Conserved Domains (1) summary
    cd14717
    Location:46 → 115
    bZIP_Maf_small; Basic leucine zipper (bZIP) domain of small musculoaponeurotic fibrosarcoma (Maf) proteins: a DNA-binding and dimerization domain
Nucleotide Protein Strain
Heading Accession and Version

Gene LinkOut

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