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CG9701 [ Drosophila melanogaster (fruit fly) ]

Gene ID: 39872, updated on 4-Apr-2024

Summary

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Official Symbol
CG9701provided by FlyBase
Primary source
FLYBASE:FBgn0036659
Locus tag
Dmel_CG9701
See related
AllianceGenome:FB:FBgn0036659
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Drosophila melanogaster
Lineage
Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
Also known as
Dmel\CG9701; Dmel_CG9701; klotho
Summary
Predicted to enable beta-glucosidase activity. Predicted to be involved in carbohydrate metabolic process. Is expressed in embryonic proventriculus and gastric caecum. Human ortholog(s) of this gene implicated in congenital lactase deficiency; coronary artery disease; intracranial embolism; and spondylosis. Orthologous to several human genes including LCTL (lactase like). [provided by Alliance of Genome Resources, Apr 2022]
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Genomic context

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Location:
73C2-73C2; 3-44 cM
Exon count:
4
Annotation release Status Assembly Chr Location
Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 3L NT_037436.4 (16733546..16739364)
Release 5.57 previous assembly Release 5 (GCF_000001215.2) 3L NT_037436.3 (16726646..16732464)

Chromosome 3L - NT_037436.4Genomic Context describing neighboring genes Neighboring gene Peptidoglycan recognition protein SB1 Neighboring gene Dead box protein 73D Neighboring gene uncharacterized protein Neighboring gene long non-coding RNA:CR46214

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Transporters and tubule crystals in the insect Malpighian tubule. Reynolds CJ, et al. Curr Opin Insect Sci, 2021 Oct. PMID 34044181, Free PMC Article
  2. Age-dependent changes in the transcription profile of long-lived Drosophila over-expressing glutamate cysteine ligase. Radyuk SN, et al. Mech Ageing Dev, 2012 Jun. PMID 22579812
  3. Flying Together: Drosophila as a Tool to Understand the Genetics of Human Alcoholism. Lathen DR, et al. Int J Mol Sci, 2020 Sep 11. PMID 32932795, Free PMC Article
  4. Identification of Genes Contributing to a Long Circadian Period in Drosophila Melanogaster. Kumar S, et al. J Biol Rhythms, 2021 Jun. PMID 33274675, Free PMC Article
  5. Microgravity simulation by diamagnetic levitation: effects of a strong gradient magnetic field on the transcriptional profile of Drosophila melanogaster. Herranz R, et al. BMC Genomics, 2012 Feb 1. PMID 22296880, Free PMC Article

See all (32) citations in PubMed

GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by FlyBase

Function Evidence Code Pubs
enables beta-glucosidase activity IBA
Inferred from Biological aspect of Ancestor
more info
  
enables hydrolase activity, hydrolyzing O-glycosyl compounds IEA
Inferred from Electronic Annotation
more info
  
Process Evidence Code Pubs
involved_in carbohydrate metabolic process IEA
Inferred from Electronic Annotation
more info
  

General protein information

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Preferred Names
uncharacterized protein
Names
CG9701-PA
NP_648918.1

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NT_037436.4 Reference assembly

    Range
    16733546..16739364
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_140661.3 → NP_648918.1  uncharacterized protein Dmel_CG9701 [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_648918.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    Q8SZX2, Q9VV98
    Related
    FBpp0075080
    Conserved Domains (1) summary
    cl23725
    Location:22 → 492
    Glyco_hydro_1; Glycosyl hydrolase family 1
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q9VV98 Q9VV98

Gene LinkOut

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