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TGFA transforming growth factor alpha [ Sus scrofa (pig) ]

Gene ID: 397484, updated on 5-Mar-2024

Summary

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Official Symbol
TGFAprovided by VGNC
Official Full Name
transforming growth factor alphaprovided by VGNC
Primary source
VGNC:VGNC:93928
See related
Ensembl:ENSSSCG00000008326
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Sus scrofa
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Artiodactyla; Suina; Suidae; Sus
Expression
Biased expression in spleen (RPKM 4.1), ovary (RPKM 2.8) and 4 other tissues See more
Orthologs
human mouse all
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Genomic context

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Location:
chromosome: 3
Exon count:
6
Annotation release Status Assembly Chr Location
106 current Sscrofa11.1 (GCF_000003025.6) 3 NC_010445.4 (71948232..72054257)
105 previous assembly Sscrofa10.2 (GCF_000003025.5) 3 NC_010445.3 (75409715..75437890, complement)

Chromosome 3 - NC_010445.4Genomic Context describing neighboring genes Neighboring gene folliculogenesis specific bHLH transcription factor Neighboring gene adducin 2 Neighboring gene uncharacterized LOC110259992 Neighboring gene uncharacterized LOC110260138 Neighboring gene family with sequence similarity 136 member A

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: Transcriptome data used for gene annotation
  • Description: Nine kinds of tissues and a mixture of multiple tissues were sequenced for genome annotation
  • BioProject: PRJNA311523
  • Publication: PMID 27646534
  • Analysis date: Thu Dec 14 17:10:49 2017

Bibliography

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Related articles in PubMed

  1. Molecular cloning and tissue distribution of pig transforming growth factor alpha. Vaughan TJ, et al. Biochem J, 1993 Dec 15. PMID 8280083, Free PMC Article
  2. Expression of FGF2 and TGFalpha and testis morphology during testicular hypertrophy subsequent to hemicastration in the neonatal boar. Wells R, et al. Mol Reprod Dev, 2008 Jun. PMID 18278782
  3. PEDE (Pig EST Data Explorer) has been expanded into Pig Expression Data Explorer, including 10 147 porcine full-length cDNA sequences. Uenishi H, et al. Nucleic Acids Res, 2007 Jan. PMID 17145712, Free PMC Article
  4. PEDE (Pig EST Data Explorer): construction of a database for ESTs derived from porcine full-length cDNA libraries. Uenishi H, et al. Nucleic Acids Res, 2004 Jan 1. PMID 14681463, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Markers

Homology

Gene Ontology Provided by RefSeq

Process Evidence Code Pubs
involved_in epidermal growth factor receptor signaling pathway IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in positive regulation of cell population proliferation IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in positive regulation of epidermal growth factor-activated receptor activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in positive regulation of mitotic nuclear division IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
protransforming growth factor alpha

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_214251.1 → NP_999416.1  protransforming growth factor alpha precursor

    See identical proteins and their annotated locations for NP_999416.1

    Status: PROVISIONAL

    Source sequence(s)
    X71014
    UniProtKB/Swiss-Prot
    Q06922
    UniProtKB/TrEMBL
    A0A8D0K2Q4
    Related
    ENSSSCP00000008889.2, ENSSSCT00000009118.4
    Conserved Domains (2) summary
    PHA02887
    Location:44 → 83
    PHA02887; EGF-like protein; Provisional
    PHA03099
    Location:47 → 121
    PHA03099; epidermal growth factor-like protein (EGF-like protein); Provisional

RefSeqs of Annotated Genomes: Sus scrofa Annotation Release 106 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference Sscrofa11.1 Primary Assembly

Genomic

  1. NC_010445.4 Reference Sscrofa11.1 Primary Assembly

    Range
    71948232..72054257
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_021085860.1 → XP_020941519.1  protransforming growth factor alpha isoform X1

    UniProtKB/TrEMBL
    A0A8D0K2Q4
    Conserved Domains (1) summary
    cl28647
    Location:43 → 82
    PHA02887; EGF-like protein; Provisional
Nucleotide Protein Strain
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q06922.1 GenPept UniProtKB/Swiss-Prot:Q06922

Gene LinkOut

The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

Molecular Biology Databases
Miscellaneous