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MYL12A myosin, light chain 12A, regulatory, non-sarcomeric [ Gallus gallus (chicken) ]

Gene ID: 396284, updated on 3-Apr-2024

Summary

Official Symbol
MYL12Aprovided by CGNC
Official Full Name
myosin, light chain 12A, regulatory, non-sarcomericprovided by CGNC
Primary source
CGNC:49735
See related
Ensembl:ENSGALG00010001297
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Gallus gallus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda; Coelurosauria; Aves; Neognathae; Galloanserae; Galliformes; Phasianidae; Phasianinae; Gallus
Also known as
G1; MLC-2; MRCL3
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Genomic context

Location:
chromosome: 2
Exon count:
4
Annotation release Status Assembly Chr Location
106 current bGalGal1.mat.broiler.GRCg7b (GCF_016699485.2) 2 NC_052533.1 (100505446..100512629, complement)
106 current bGalGal1.pat.whiteleghornlayer.GRCg7w (GCF_016700215.2) 2 NC_052574.1 (100565542..100572707, complement)

Chromosome 2 - NC_052533.1Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC107052699 Neighboring gene uncharacterized LOC121110052 Neighboring gene myosin light chain 12B Neighboring gene uncharacterized LOC121110054 Neighboring gene myomesin 1 Neighboring gene lipin 2

Genomic regions, transcripts, and products

Pathways from PubChem

General protein information

Preferred Names
myosin regulatory light chain 2, smooth muscle minor isoform
Names
isoform L20-B
isoform L20-B1
myosin regulatory light chain MRCL3

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_205341.4NP_990672.1  myosin regulatory light chain 2, smooth muscle minor isoform

    See identical proteins and their annotated locations for NP_990672.1

    Status: VALIDATED

    Source sequence(s)
    JAENSK010000043
    UniProtKB/Swiss-Prot
    P24032
    UniProtKB/TrEMBL
    A0A8V0ZIV3
    Conserved Domains (1) summary
    COG5126
    Location:19169
    FRQ1; Ca2+-binding protein, EF-hand superfamily [Signal transduction mechanisms]

RefSeqs of Annotated Genomes: Gallus gallus Annotation Release 106 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference bGalGal1.mat.broiler.GRCg7b Primary Assembly

Genomic

  1. NC_052533.1 Reference bGalGal1.mat.broiler.GRCg7b Primary Assembly

    Range
    100505446..100512629 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_015282584.4XP_015138070.1  myosin regulatory light chain 2, smooth muscle minor isoform isoform X1

    UniProtKB/TrEMBL
    A0A1L1RM08, A0A8V0ZIV3
    Related
    ENSGALP00010001537.1, ENSGALT00010003001.1
    Conserved Domains (3) summary
    COG5126
    Location:45195
    FRQ1; Ca2+-binding protein, EF-hand superfamily [Signal transduction mechanisms]
    cd00051
    Location:59103
    EFh; EF-hand, calcium binding motif; A diverse superfamily of calcium sensors and calcium signal modulators; most examples in this alignment model have 2 active canonical EF hands. Ca2+ binding induces a conformational change in the EF-hand motif, leading to ...
    cl08302
    Location:129190
    EFh; EF-hand, calcium binding motif; A diverse superfamily of calcium sensors and calcium signal modulators; most examples in this alignment model have 2 active canonical EF hands. Ca2+ binding induces a conformational change in the EF-hand motif, leading to ...

Alternate bGalGal1.pat.whiteleghornlayer.GRCg7w

Genomic

  1. NC_052574.1 Alternate bGalGal1.pat.whiteleghornlayer.GRCg7w

    Range
    100565542..100572707 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_046910477.1XP_046766433.1  myosin regulatory light chain 2, smooth muscle minor isoform isoform X1

    UniProtKB/TrEMBL
    A0A1L1RM08