ampd1 adenosine monophosphate deaminase 1 (isoform M) [Danio rerio (zebrafish)] - Gene

Summary

Official Symbol: ampd1provided by ZNC
Official Full Name: adenosine monophosphate deaminase 1 (isoform M)provided by ZNC
Primary source: ZFIN:ZDB-GENE-040426-1906
See related: Ensembl:ENSDARG00000033832 AllianceGenome:ZFIN:ZDB-GENE-040426-1906
Gene type: protein coding
RefSeq status: PROVISIONAL
Organism: Danio rerio
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
Also known as: zgc:77905
Summary: Predicted to enable AMP deaminase activity. Predicted to be involved in AMP metabolic process and IMP biosynthetic process. Predicted to act upstream of or within purine ribonucleoside monophosphate biosynthetic process. Predicted to be active in cytosol. Is expressed in cephalic musculature; myotome; pectoral fin musculature; and trunk musculature. Orthologous to human AMPD1 (adenosine monophosphate deaminase 1). [provided by Alliance of Genome Resources, Apr 2022]
Orthologs: human mouse all
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Genomic context

Location:: chromosome: 8

Exon count:: 17

Annotation release	Status	Assembly	Chr	Location
106	current	GRCz11 (GCF_000002035.6)	8	NC_007119.7 (11080571..11112024, complement)
105	previous assembly	GRCz10 (GCF_000002035.5)	8	NC_007119.6 (11042866..11074319, complement)

Chromosome 8 - NC_007119.7 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

Expression

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See details

Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
BioProject: PRJEB1986
Analysis date: Fri Dec 8 19:48:10 2017

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

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General gene information

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Markers

MARC_6295-6296:992007206:1 (e-PCR)
- UniSTS:231224

MARC_6295-6296:997299508:1 (e-PCR)
- UniSTS:231224

fi70e06.x1 (e-PCR)
- UniSTS:197886

Gene Ontology Provided by ZFIN

Function	Evidence Code	Pubs
enables AMP deaminase activity	IBA Inferred from Biological aspect of Ancestor more info
enables AMP deaminase activity	IEA Inferred from Electronic Annotation more info
enables deaminase activity	IEA Inferred from Electronic Annotation more info
enables hydrolase activity	IEA Inferred from Electronic Annotation more info
enables metal ion binding	IEA Inferred from Electronic Annotation more info

Process	Evidence Code	Pubs
involved_in AMP metabolic process	IBA Inferred from Biological aspect of Ancestor more info
involved_in IMP biosynthetic process	IBA Inferred from Biological aspect of Ancestor more info
acts_upstream_of_or_within IMP salvage	IEA Inferred from Electronic Annotation more info
involved_in IMP salvage	IEA Inferred from Electronic Annotation more info
acts_upstream_of_or_within purine ribonucleoside monophosphate biosynthetic process	IEA Inferred from Electronic Annotation more info

Component	Evidence Code	Pubs
is_active_in cytosol	IBA Inferred from Biological aspect of Ancestor more info

General protein information

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Preferred Names: AMP deaminase 1

NP_957187.1

EC 3.5.4.6

XP_017212786.1

EC 3.5.4.6

XP_017212787.1

EC 3.5.4.6

XP_017212788.1

EC 3.5.4.6

XP_017212789.1

EC 3.5.4.6

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

NM_200893.1 → NP_957187.1 AMP deaminase 1

See identical proteins and their annotated locations for NP_957187.1

Status: PROVISIONAL

Source sequence(s)

BC063996

UniProtKB/TrEMBL

A0A8M1PBX8, Q6P3G5

Related

ENSDARP00000042754.6, ENSDART00000042755.7

Conserved Domains (2) summary

PLN03055
Location:102 → 714

PLN03055; AMP deaminase; Provisional

cl00281
Location:102 → 710

metallo-dependent_hydrolases; Superfamily of metallo-dependent hydrolases (also called amidohydrolase superfamily) is a large group of proteins that show conservation in their 3-dimensional fold (TIM barrel) and in details of their active site. The vast majority of the members have a ...