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PF3D7_0612700 6-cysteine protein P12 [ Plasmodium falciparum 3D7 ]

Gene ID: 3885775, updated on 25-Jan-2024

Summary

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Gene symbol
PF3D7_0612700
Gene description
6-cysteine protein P12
Locus tag
PF3D7_0612700
Gene type
protein coding
RNA name
6-cysteine protein P12
RefSeq status
PROVISIONAL
Organism
Plasmodium falciparum 3D7 (isolate: 3D7)
Lineage
Eukaryota; Sar; Alveolata; Apicomplexa; Aconoidasida; Haemosporida; Plasmodiidae; Plasmodium; Plasmodium (Laverania)
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Genomic context

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Location:
chromosome: 6
Exon count:
1
Sequence:
Chromosome: 6; NC_004327.3 (525987..527030, complement)

Chromosome 6 - NC_004327.3Genomic Context describing neighboring genes Neighboring gene conserved Plasmodium protein, unknown function Neighboring gene cytoplasmic tRNA 2-thiolation protein 1, putative Neighboring gene 6-cysteine protein Neighboring gene nucleolar GTP-binding protein 1, putative

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_004327.3

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?
  1. Nanobody generation and structural characterization of Plasmodium falciparum 6-cysteine protein Pf12p.
    Title: Nanobody generation and structural characterization of Plasmodium falciparum 6-cysteine protein Pf12p.
  2. the localization and structure of Pf12 and details of its interaction with Pf41 reveal important insight into the structural and functional properties of this archetypal member of the 6-Cys protein family.
    Title: Structural and biochemical characterization of Plasmodium falciparum 12 (Pf12) reveals a unique interdomain organization and the potential for an antiparallel arrangement with Pf41.
Submit: New GeneRIF Correction

General gene information

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Markers

Homology

Gene Ontology Provided by GeneDB

Function Evidence Code Pubs
enables protein binding IPI
Inferred from Physical Interaction
more info
 PubMed 
Process Evidence Code Pubs
acts_upstream_of_or_within symbiont entry into host IMP
Inferred from Mutant Phenotype
more info
 PubMed 
Component Evidence Code Pubs
located_in cell surface IDA
Inferred from Direct Assay
more info
 PubMed 
located_in plasma membrane IDA
Inferred from Direct Assay
more info
 PubMed 
located_in rhoptry IDA
Inferred from Direct Assay
more info
 PubMed 
located_in symbiont-containing vacuolar space IDA
Inferred from Direct Assay
more info
 PubMed 

General protein information

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Preferred Names
6-cysteine protein P12

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_004327.3 Reference assembly

    Range
    525987..527030 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_961021.1 → XP_966114.1  6-cysteine protein P12 [Plasmodium falciparum 3D7]

    See identical proteins and their annotated locations for XP_966114.1

    Status: PROVISIONAL

    UniProtKB/Swiss-Prot
    C6KSX0
    UniProtKB/TrEMBL
    A0A024VUS4, A0A024WBX4, A0A024WTY7, A0A024XC13, A0A0L0CW30, A0A0L1ID76, A0A0L7K5Y3, A0A0L7M6A2, W4IM91, W4ITU7, W7FGQ9, W7GAI1, W7JFN6, W7JXS2
    Conserved Domains (1) summary
    PTZ00442
    Location:3 → 347
    PTZ00442; sexual stage antigen s48/45-like protein; Provisional
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
C6KSX0.1

Gene LinkOut

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Molecular Biology Databases
Research Materials