Gene description

7-cyano-7-deazaguanine reductase

Locus Tag

BTH_I0548

Gene type

protein coding

RefSeq status

Provisional

Organism

Burkholderia thailandensis E264

Lineage

Bacteria; Proteobacteria; Betaproteobacteria; Burkholderiales; Burkholderiaceae; Burkholderia; pseudomallei group

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Names

7-cyano-7-deazaguanine reductase

YP_441105.1

catalyzes the NADPH-dependent reduction of 7-cyano-7-deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1) in queuosine biosynthesis

Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

This section includes genomic Reference Sequences (RefSeqs) from all assemblies on which this gene is annotated, such as RefSeqs for chromosomes and scaffolds (contigs) from both reference and alternate assemblies. Model RNAs and proteins are also reported here.

mRNA and Protein(s)

1. YP_441105.1 7-cyano-7-deazaguanine reductase [Burkholderia thailandensis E264]

   UniProtKB/Swiss-Prot

   Q2T144

   Conserved Domains (3) summary

   COG2904
   Location:4 – 129
   Blast Score: 481

   COG2904; Uncharacterized protein conserved in bacteria [Function unknown]

   PRK11792
   Location:3 – 274
   Blast Score: 1351

   queF; 7-cyano-7-deazaguanine reductase; Provisional

   cl00263
   Location:163 – 274
   Blast Score: 373

   TFold; Tunnelling fold (T-fold). The five known T-folds are found in five different enzymes with different functions: dihydroneopterin-triphosphate epimerase (DHNTPE), dihydroneopterin aldolase (DHNA) , GTP cyclohydrolase I (GTPCH-1), 6-pyrovoyl...