P2RX4 purinergic receptor P2X 4 [Gallus gallus (chicken)] - Gene

Summary

Symbol: P2RX4provided by CGNC
Full Name: purinergic receptor P2X 4provided by CGNC
Primary source: CGNC:2857
See related: Ensembl:ENSGALG00010025212
Gene type: protein coding
RefSeq status: VALIDATED
Organism: Gallus gallus
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda; Coelurosauria; Aves; Neognathae; Galloanserae; Galliformes; Phasianidae; Phasianinae; Gallus
Orthologs: human mouse all
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Genomic context

Location:: chromosome: 15

Exon count:: 12

Annotation release	Status	Assembly	Chr	Location
106	current	bGalGal1.mat.broiler.GRCg7b (GCF_016699485.2)	15	NC_052546.1 (5446554..5452970)
106	current	bGalGal1.pat.whiteleghornlayer.GRCg7w (GCF_016700215.2)	15	NC_052587.1 (5457203..5463620)

Chromosome 15 - NC_052546.1 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Data suggest a role of ionotropic purinergic signalling of P2X(4) in the generation of ATP-dependent Ca(2+) transients of differentiating chondroblasts.
Title: Ionotropic purinergic receptor P2X4 is involved in the regulation of chondrogenesis in chicken micromass cell cultures.

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General gene information

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Gene Ontology Provided by RefSeq

Function	Evidence Code	Pubs
enables ATP binding	IEA Inferred from Electronic Annotation more info	PubMed
enables extracellularly ATP-gated monoatomic cation channel activity	IEA Inferred from Electronic Annotation more info	PubMed
enables purinergic nucleotide receptor activity	IEA Inferred from Electronic Annotation more info	PubMed

Process	Evidence Code	Pubs
involved_in monoatomic cation transmembrane transport	IEA Inferred from Electronic Annotation more info	PubMed
involved_in response to ATP	IEA Inferred from Electronic Annotation more info	PubMed

Component	Evidence Code	Pubs
located_in nuclear inner membrane	IEA Inferred from Electronic Annotation more info	PubMed
located_in plasma membrane	IEA Inferred from Electronic Annotation more info	PubMed

General protein information

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Preferred Names: P2X purinoceptor 4

Names: purinergic receptor P2X, ligand-gated ion channel, 4

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

NM_001397754.1 → NP_001384683.1 P2X purinoceptor 4 isoform 2

Status: VALIDATED

Source sequence(s)

JAENSK010000260
NM_001397755.1 → NP_001384684.1 P2X purinoceptor 4 isoform 3

Status: VALIDATED

Source sequence(s)

JAENSK010000260
NM_204291.2 → NP_989622.2 P2X purinoceptor 4 isoform 1

Status: VALIDATED

Source sequence(s)

JAENSK010000260

UniProtKB/TrEMBL

A0A8V1A1U9

Related

ENSGALP00010037994.1, ENSGALT00010061502.1

RNA

NR_174017.1 RNA Sequence

Status: VALIDATED

Source sequence(s)

JAENSK010000260
NR_174018.1 RNA Sequence

Status: VALIDATED

Source sequence(s)

JAENSK010000260