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Slc25a30 solute carrier family 25, member 30 [ Rattus norvegicus (Norway rat) ]

Gene ID: 361074, updated on 13-Apr-2024

Summary

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Symbol
Slc25a30provided by RGD
Full Name
solute carrier family 25, member 30provided by RGD
Primary source
RGD:1359702
See related
Ensembl:ENSRNOG00000001052 AllianceGenome:RGD:1359702
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Rattus norvegicus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
Summary
Predicted to enable C4-dicarboxylate transmembrane transporter activity; antiporter activity; and sulfur compound transmembrane transporter activity. Predicted to be involved in anion transport. Predicted to be located in mitochondrion. Orthologous to human SLC25A30 (solute carrier family 25 member 30). [provided by Alliance of Genome Resources, Apr 2022]
Expression
Biased expression in Adrenal (RPKM 602.1), Kidney (RPKM 540.1) and 9 other tissues See more
Orthologs
human mouse all
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Genomic context

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Location:
15q11
Exon count:
12
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCr8 (GCF_036323735.1) 15 NC_086033.1 (57486346..57508981, complement)
RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 15 NC_051350.1 (51076998..51099613, complement)
106 previous assembly Rnor_6.0 (GCF_000001895.5) 15 NC_005114.4 (57811612..57834173, complement)

Chromosome 15 - NC_086033.1Genomic Context describing neighboring genes Neighboring gene siah E3 ubiquitin protein ligase family member 3 Neighboring gene uncharacterized LOC120097040 Neighboring gene chibby family member 2 Neighboring gene GABA type A receptor associated protein like 2, pseudogene 2 Neighboring gene glutamate-rich 6B Neighboring gene component of oligomeric golgi complex 3 Neighboring gene uncharacterized LOC102552389 Neighboring gene small nucleolar RNA, H/ACA box 31 Neighboring gene tumor protein, translationally-controlled 1

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
  • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
  • BioProject: PRJNA238328
  • Publication: PMID 24510058
  • Analysis date: Mon Jun 6 17:44:12 2016

Bibliography

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Related articles in PubMed

  1. A new renal mitochondrial carrier, KMCP1, is up-regulated during tubular cell regeneration and induction of antioxidant enzymes. Haguenauer A, et al. J Biol Chem, 2005 Jun 10. PMID 15809292
  2. Noncanonical and canonical splice sites: a novel mutation at the rare noncanonical splice-donor cut site (IVS4+1A>G) of SEDL causes variable splicing isoforms in X-linked spondyloepiphyseal dysplasia tarda. Xiong F, et al. Eur J Hum Genet, 2009 Apr. PMID 19002213, Free PMC Article
  3. A mitochondrial protein compendium elucidates complex I disease biology. Pagliarini DJ, et al. Cell, 2008 Jul 11. PMID 18614015, Free PMC Article
  4. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article
  5. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Markers

Homology

Gene Ontology Provided by RGD

Function Evidence Code Pubs
enables solute:inorganic anion antiporter activity ISO
Inferred from Sequence Orthology
more info
  
enables solute:inorganic anion antiporter activity ISS
Inferred from Sequence or Structural Similarity
more info
  
enables transmembrane transporter activity IBA
Inferred from Biological aspect of Ancestor
more info
  
Process Evidence Code Pubs
involved_in inorganic anion transport ISO
Inferred from Sequence Orthology
more info
  
involved_in inorganic anion transport ISS
Inferred from Sequence or Structural Similarity
more info
  
involved_in transmembrane transport IEA
Inferred from Electronic Annotation
more info
  
Component Evidence Code Pubs
located_in mitochondrial inner membrane IEA
Inferred from Electronic Annotation
more info
  
located_in mitochondrion ISO
Inferred from Sequence Orthology
more info
  

General protein information

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Preferred Names
kidney mitochondrial carrier protein 1

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001013187.2 → NP_001013205.1  kidney mitochondrial carrier protein 1

    See identical proteins and their annotated locations for NP_001013205.1

    Status: PROVISIONAL

    Source sequence(s)
    JAXUCZ010000015
    UniProtKB/Swiss-Prot
    Q5PQM9
    UniProtKB/TrEMBL
    F1LR53
    Related
    ENSRNOP00000097957.1, ENSRNOT00000104191.1
    Conserved Domains (2) summary
    PTZ00169
    Location:9 → 289
    PTZ00169; ADP/ATP transporter on adenylate translocase; Provisional
    pfam00153
    Location:199 → 289
    Mito_carr; Mitochondrial carrier protein

RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCr8

Genomic

  1. NC_086033.1 Reference GRCr8

    Range
    57486346..57508981 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_008770873.4 → XP_008769095.2  kidney mitochondrial carrier protein 1 isoform X1

    UniProtKB/Swiss-Prot
    Q5PQM9
    UniProtKB/TrEMBL
    F1LR53
    Conserved Domains (2) summary
    PTZ00169
    Location:9 → 289
    PTZ00169; ADP/ATP transporter on adenylate translocase; Provisional
    pfam00153
    Location:199 → 289
    Mito_carr; Mitochondrial carrier protein

  2. XM_063274438.1 → XP_063130508.1  kidney mitochondrial carrier protein 1 isoform X1

    UniProtKB/Swiss-Prot
    Q5PQM9
Nucleotide Protein Strain
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q5PQM9.1 GenPept UniProtKB/Swiss-Prot:Q5PQM9

Gene LinkOut

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