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CG1441 [ Drosophila melanogaster (fruit fly) ]

Gene ID: 36029, updated on 4-Apr-2024

Summary

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Official Symbol
CG1441provided by FlyBase
Primary source
FLYBASE:FBgn0033464
Locus tag
Dmel_CG1441
See related
AllianceGenome:FB:FBgn0033464
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Drosophila melanogaster
Lineage
Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
Also known as
Dmel\CG1441
Summary
Predicted to enable fatty-acyl-CoA reductase (alcohol-forming) activity. Predicted to be involved in long-chain fatty-acyl-CoA metabolic process. Predicted to be active in peroxisome. Is expressed in adult fat body; adult head; embryonic epidermis; embryonic/larval posterior spiracle; and sensory nervous system primordium. Orthologous to human FAR1 (fatty acyl-CoA reductase 1). [provided by Alliance of Genome Resources, Apr 2022]
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Genomic context

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Location:
46C4-46C4; 2-61 cM
Exon count:
6
Annotation release Status Assembly Chr Location
Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 2R NT_033778.4 (9899018..9903287, complement)
Release 5.57 previous assembly Release 5 (GCF_000001215.2) 2R NT_033778.3 (5786523..5790792, complement)

Chromosome 2R - NT_033778.4Genomic Context describing neighboring genes Neighboring gene uncharacterized protein Neighboring gene uncharacterized protein Neighboring gene telomere ends associated Neighboring gene FMRFamide Neighboring gene Electron transfer flavoprotein-ubiquinone oxidoreductase

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Birth-and-Death Evolution of the Fatty Acyl-CoA Reductase (FAR) Gene Family and Diversification of Cuticular Hydrocarbon Synthesis in Drosophila. Finet C, et al. Genome Biol Evol, 2019 Jun 1. PMID 31076758, Free PMC Article
  2. tBRD-1 and tBRD-2 regulate expression of genes necessary for spermatid differentiation. Theofel I, et al. Biol Open, 2017 Apr 15. PMID 28235844, Free PMC Article
  3. tBRD-1 selectively controls gene activity in the Drosophila testis and interacts with two new members of the bromodomain and extra-terminal (BET) family. Theofel I, et al. PLoS One, 2014. PMID 25251222, Free PMC Article
  4. The ups and downs of daily life: profiling circadian gene expression in Drosophila. Etter PD, et al. Bioessays, 2002 Jun. PMID 12111731
  5. Transcriptome analysis provides insights for understanding the adverse effects of endosulfan in Drosophila melanogaster. Sharma A, et al. Chemosphere, 2011 Jan. PMID 21036383

See all (35) citations in PubMed

GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by FlyBase

Function Evidence Code Pubs
enables alcohol-forming very long-chain fatty acyl-CoA reductase activity IBA
Inferred from Biological aspect of Ancestor
more info
  
enables alcohol-forming very long-chain fatty acyl-CoA reductase activity IEA
Inferred from Electronic Annotation
more info
  
enables alcohol-forming very long-chain fatty acyl-CoA reductase activity ISS
Inferred from Sequence or Structural Similarity
more info
 PubMed 
Process Evidence Code Pubs
involved_in long-chain fatty-acyl-CoA metabolic process IBA
Inferred from Biological aspect of Ancestor
more info
  
Component Evidence Code Pubs
is_active_in peroxisome IBA
Inferred from Biological aspect of Ancestor
more info
  

General protein information

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Preferred Names
uncharacterized protein
Names
CG1441-PA
CG1441-PB

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NT_033778.4 Reference assembly

    Range
    9899018..9903287 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_136691.4 → NP_610535.1  uncharacterized protein Dmel_CG1441, isoform B [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_610535.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    Q7K3T3
    Related
    FBpp0087534
    Conserved Domains (3) summary
    cd05236
    Location:35 → 348
    FAR-N_SDR_e; fatty acyl CoA reductases (FARs), extended (e) SDRs
    PLN02996
    Location:24 → 464
    PLN02996; fatty acyl-CoA reductase
    pfam03015
    Location:385 → 475
    Sterile; Male sterility protein

  2. NM_165720.4 → NP_724856.1  uncharacterized protein Dmel_CG1441, isoform A [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_724856.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    Q7K3T3
    Related
    FBpp0087533
    Conserved Domains (3) summary
    cd05236
    Location:35 → 348
    FAR-N_SDR_e; fatty acyl CoA reductases (FARs), extended (e) SDRs
    PLN02996
    Location:24 → 464
    PLN02996; fatty acyl-CoA reductase
    pfam03015
    Location:385 → 475
    Sterile; Male sterility protein
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q7K3T3 Q7K3T3

Gene LinkOut

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