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bin3 bridging integrator 3 [ Danio rerio (zebrafish) ]

Gene ID: 323976, updated on 11-Apr-2024

Summary

Official Symbol
bin3provided by ZNC
Official Full Name
bridging integrator 3provided by ZNC
Primary source
ZFIN:ZDB-GENE-030131-2696
See related
Ensembl:ENSDARG00000099651 AllianceGenome:ZFIN:ZDB-GENE-030131-2696
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Danio rerio
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
Also known as
fc15h07; wu:fc15h07; zgc:158415
Summary
Predicted to contribute to lipid binding activity. Predicted to be involved in actin cortical patch localization; endocytosis; and plasma membrane tubulation. Predicted to be located in cytoplasm. Orthologous to human BIN3 (bridging integrator 3). [provided by Alliance of Genome Resources, Apr 2022]
Annotation information
Annotation category: partial on reference assembly
Orthologs
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Genomic context

Location:
chromosome: 8
Exon count:
15
Annotation release Status Assembly Chr Location
106 current GRCz11 (GCF_000002035.6) 8 NC_007119.7 (50743037..50839565)
105 previous assembly GRCz10 (GCF_000002035.5) 8 NC_007119.6 (50823939..50851228, complement)

Chromosome 8 - NC_007119.7Genomic Context describing neighboring genes Neighboring gene phosphatidylethanolamine binding protein 4 Neighboring gene early growth response 3 Neighboring gene acyl-CoA synthetase long chain family member 2 Neighboring gene protein kinase cGMP-dependent 1, like

Genomic regions, transcripts, and products

Expression

  • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • BioProject: PRJEB1986
  • Analysis date: Fri Dec 8 19:48:10 2017

General gene information

Markers

Gene Ontology Provided by ZFIN

Function Evidence Code Pubs
contributes_to lipid binding IBA
Inferred from Biological aspect of Ancestor
more info
 
Process Evidence Code Pubs
involved_in actin cortical patch localization IBA
Inferred from Biological aspect of Ancestor
more info
 
acts_upstream_of_or_within actin cortical patch localization IEA
Inferred from Electronic Annotation
more info
 
involved_in endocytosis IBA
Inferred from Biological aspect of Ancestor
more info
 
acts_upstream_of_or_within endocytosis IEA
Inferred from Electronic Annotation
more info
 
involved_in plasma membrane tubulation IBA
Inferred from Biological aspect of Ancestor
more info
 
Component Evidence Code Pubs
is_active_in actin cytoskeleton IBA
Inferred from Biological aspect of Ancestor
more info
 
located_in cytoplasm IEA
Inferred from Electronic Annotation
more info
 
located_in cytoskeleton IEA
Inferred from Electronic Annotation
more info
 

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001123044.2NP_001116516.1  bridging integrator 3

    See identical proteins and their annotated locations for NP_001116516.1

    Status: VALIDATED

    Source sequence(s)
    CABZ01070717, CABZ01070718, CABZ01113849, CU855695
    UniProtKB/TrEMBL
    A0A0G2KTR0, A0A8N7UYU5, B1H1H2
    Related
    ENSDARP00000135811.2, ENSDART00000160612.2
    Conserved Domains (1) summary
    cd07590
    Location:12236
    BAR_Bin3; The Bin/Amphiphysin/Rvs (BAR) domain of Bridging integrator 3

RefSeqs of Annotated Genomes: Danio rerio Annotation Release 106 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCz11 Primary Assembly

Genomic

  1. NC_007119.7 Reference GRCz11 Primary Assembly

    Range
    50743037..50839565
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)