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CG12111 [ Drosophila melanogaster (fruit fly) ]

Gene ID: 31796, updated on 4-Apr-2024

Summary

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Official Symbol
CG12111provided by FlyBase
Primary source
FLYBASE:FBgn0030050
Locus tag
Dmel_CG12111
See related
AllianceGenome:FB:FBgn0030050
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Drosophila melanogaster
Lineage
Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
Also known as
Dmel\CG12111
Summary
Predicted to enable carbohydrate binding activity. Predicted to be active in external side of plasma membrane. Is expressed in adult head and organism. Orthologous to human CLEC6A (C-type lectin domain containing 6A) and CLEC4E (C-type lectin domain family 4 member E). [provided by Alliance of Genome Resources, Apr 2022]
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Genomic context

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Location:
7F4-7F5; 1-23 cM
Exon count:
2
Annotation release Status Assembly Chr Location
Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) X NC_004354.4 (8570208..8570948, complement)
Release 5.57 previous assembly Release 5 (GCF_000001215.2) X NC_004354.3 (8464241..8464981, complement)

Chromosome X - NC_004354.4Genomic Context describing neighboring genes Neighboring gene uncharacterized protein Neighboring gene Topoisomerase related function 4-1 Neighboring gene antisense RNA:CR46195 Neighboring gene Serine Protease Immune Response Integrator Neighboring gene uncharacterized protein

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Lectin-like proteins in model organisms: implications for evolution of carbohydrate-binding activity. Dodd RB, et al. Glycobiology, 2001 May. PMID 11425795
  2. Comparative genomic analysis of C-type lectin-domain genes in seven holometabolous insect species. Lu Y, et al. Insect Biochem Mol Biol, 2020 Nov. PMID 32841718
  3. Participation of a galactose-specific C-type lectin in Drosophila immunity. Tanji T, et al. Biochem J, 2006 May 15. PMID 16475980, Free PMC Article
  4. The chromosomal high-affinity binding sites for the Drosophila dosage compensation complex. Straub T, et al. PLoS Genet, 2008 Dec. PMID 19079572, Free PMC Article
  5. Reproductive status alters transcriptomic response to infection in female Drosophila melanogaster. Short SM, et al. G3 (Bethesda), 2013 May 20. PMID 23550122, Free PMC Article

See all (27) citations in PubMed

GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by FlyBase

Function Evidence Code Pubs
enables carbohydrate binding IBA
Inferred from Biological aspect of Ancestor
more info
  
enables carbohydrate binding ISS
Inferred from Sequence or Structural Similarity
more info
 PubMed 
Process Evidence Code Pubs
involved_in biological process involved in interspecies interaction between organisms IBA
Inferred from Biological aspect of Ancestor
more info
  
Component Evidence Code Pubs
is_active_in external side of plasma membrane IBA
Inferred from Biological aspect of Ancestor
more info
  

General protein information

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Preferred Names
uncharacterized protein
Names
CG12111-PA
CG12111-PB

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_004354.4 Reference assembly

    Range
    8570208..8570948 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001272412.1 → NP_001259341.1  uncharacterized protein Dmel_CG12111, isoform B [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_001259341.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    Q9W3D8
    Conserved Domains (1) summary
    cd00037
    Location:55 → 174
    CLECT; C-type lectin (CTL)/C-type lectin-like (CTLD) domain

  2. NM_132263.4 → NP_572491.1  uncharacterized protein Dmel_CG12111, isoform A [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_572491.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    Q9W3D8
    Related
    FBpp0071176
    Conserved Domains (1) summary
    cd00037
    Location:55 → 174
    CLECT; C-type lectin (CTL)/C-type lectin-like (CTLD) domain
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q9W3D8 Q9W3D8

Gene LinkOut

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