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Jkamp JNK1/MAPK8-associated membrane protein [ Rattus norvegicus (Norway rat) ]

Gene ID: 299127, updated on 11-Apr-2024

Summary

Official Symbol
Jkampprovided by RGD
Official Full Name
JNK1/MAPK8-associated membrane proteinprovided by RGD
Primary source
RGD:1308917
See related
Ensembl:ENSRNOG00000004751 AllianceGenome:RGD:1308917
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Rattus norvegicus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
Also known as
RGD1308917
Summary
Predicted to enable ubiquitin protein ligase binding activity. Predicted to be involved in ubiquitin-dependent ERAD pathway. Predicted to be integral component of membrane. Orthologous to human JKAMP (JNK1/MAPK8 associated membrane protein). [provided by Alliance of Genome Resources, Apr 2022]
Expression
Biased expression in Brain (RPKM 179.7), Kidney (RPKM 146.3) and 9 other tissues See more
Orthologs
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Genomic context

See Jkamp in Genome Data Viewer
Location:
6q24
Exon count:
7
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCr8 (GCF_036323735.1) 6 NC_086024.1 (96383976..96397917)
RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 6 NC_051341.1 (90648043..90661985)
106 previous assembly Rnor_6.0 (GCF_000001895.5) 6 NC_005105.4 (94835845..94849784)

Chromosome 6 - NC_086024.1Genomic Context describing neighboring genes Neighboring gene 60S ribosomal protein L9 pseudogene Neighboring gene trans-L-3-hydroxyproline dehydratase Neighboring gene coiled-coil domain containing 175 Neighboring gene reticulon 1 Neighboring gene peptidylprolyl isomerase D, pseudogene 7

Genomic regions, transcripts, and products

Expression

  • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
  • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
  • BioProject: PRJNA238328
  • Publication: PMID 24510058
  • Analysis date: Mon Jun 6 17:44:12 2016

General gene information

Markers

Gene Ontology Provided by RGD

Function Evidence Code Pubs
enables ubiquitin protein ligase binding IBA
Inferred from Biological aspect of Ancestor
more info
 
enables ubiquitin protein ligase binding ISO
Inferred from Sequence Orthology
more info
 
Process Evidence Code Pubs
involved_in ERAD pathway IBA
Inferred from Biological aspect of Ancestor
more info
 
involved_in ERAD pathway ISO
Inferred from Sequence Orthology
more info
 
involved_in response to unfolded protein IEA
Inferred from Electronic Annotation
more info
 
Component Evidence Code Pubs
located_in membrane IEA
Inferred from Electronic Annotation
more info
 

General protein information

Preferred Names
JNK1/MAPK8-associated membrane protein

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001106738.1NP_001100208.1  JNK1/MAPK8-associated membrane protein

    See identical proteins and their annotated locations for NP_001100208.1

    Status: PROVISIONAL

    Source sequence(s)
    CH473947
    UniProtKB/TrEMBL
    A6HC30, D3ZZT8
    Related
    ENSRNOP00000006321.3, ENSRNOT00000006321.5
    Conserved Domains (1) summary
    pfam05571
    Location:9300
    DUF766; Protein of unknown function (DUF766)

RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCr8

Genomic

  1. NC_086024.1 Reference GRCr8

    Range
    96383976..96397917
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)