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Adgrf3 adhesion G protein-coupled receptor F3 [ Rattus norvegicus (Norway rat) ]

Gene ID: 298857, updated on 13-Apr-2024

Summary

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Official Symbol
Adgrf3provided by RGD
Official Full Name
adhesion G protein-coupled receptor F3provided by RGD
Primary source
RGD:1305868
See related
Ensembl:ENSRNOG00000024766 AllianceGenome:RGD:1305868
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Rattus norvegicus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
Also known as
Gpr113
Summary
Predicted to enable G protein-coupled receptor activity. Predicted to be involved in G protein-coupled receptor signaling pathway and cell surface receptor signaling pathway. Predicted to be located in plasma membrane. Predicted to be integral component of membrane. Orthologous to human ADGRF3 (adhesion G protein-coupled receptor F3). [provided by Alliance of Genome Resources, Apr 2022]
Expression
Biased expression in Liver (RPKM 6.9), Testes (RPKM 1.7) and 5 other tissues See more
Orthologs
human mouse all
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Genomic context

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Location:
6q14
Exon count:
14
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCr8 (GCF_036323735.1) 6 NC_086024.1 (31853018..31864441)
RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 6 NC_051341.1 (26133176..26144601)
106 previous assembly Rnor_6.0 (GCF_000001895.5) 6 NC_005105.4 (27534525..27546804)

Chromosome 6 - NC_086024.1Genomic Context describing neighboring genes Neighboring gene selenoprotein I Neighboring gene uncharacterized LOC120103489 Neighboring gene hydroxyacyl-CoA dehydrogenase trifunctional multienzyme complex subunit beta Neighboring gene hydroxyacyl-CoA dehydrogenase trifunctional multienzyme complex subunit alpha

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
  • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
  • BioProject: PRJNA238328
  • Publication: PMID 24510058
  • Analysis date: Mon Jun 6 17:44:12 2016

Bibliography

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Related articles in PubMed

  1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RGD

Function Evidence Code Pubs
enables G protein-coupled receptor activity IBA
Inferred from Biological aspect of Ancestor
more info
  
Process Evidence Code Pubs
involved_in adenylate cyclase-activating G protein-coupled receptor signaling pathway IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in cell surface receptor signaling pathway IEA
Inferred from Electronic Annotation
more info
  
Component Evidence Code Pubs
located_in membrane IEA
Inferred from Electronic Annotation
more info
  

General protein information

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Preferred Names
adhesion G-protein coupled receptor F3
Names
G protein-coupled receptor 113
probable G-protein coupled receptor 113

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001106712.2 → NP_001100182.1  adhesion G-protein coupled receptor F3 isoform 2

    See identical proteins and their annotated locations for NP_001100182.1

    Status: VALIDATED

    Source sequence(s)
    JAXUCZ010000006
    UniProtKB/TrEMBL
    A6HAE0, D3Z8X5
    Related
    ENSRNOP00000034976.4, ENSRNOT00000032829.5
    Conserved Domains (3) summary
    smart00303
    Location:544 → 591
    GPS; G-protein-coupled receptor proteolytic site domain
    cl02422
    Location:265 → 307
    HRM; Hormone receptor domain
    cl21561
    Location:599 → 843
    7tm_4; Olfactory receptor

  2. NM_001414912.1 → NP_001401841.1  adhesion G-protein coupled receptor F3 isoform 1 precursor

    Status: VALIDATED

    Source sequence(s)
    JAXUCZ010000006
    UniProtKB/TrEMBL
    A0A096MKI0
    Related
    ENSRNOP00000068523.2, ENSRNOT00000076512.3

RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCr8

Genomic

  1. NC_086024.1 Reference GRCr8

    Range
    31853018..31864441
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
Nucleotide Protein Strain
Heading Accession and Version

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