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Nop14 NOP14 nucleolar protein [ Rattus norvegicus (Norway rat) ]

Gene ID: 289724, updated on 13-Apr-2024

Summary

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Official Symbol
Nop14provided by RGD
Official Full Name
NOP14 nucleolar proteinprovided by RGD
Primary source
RGD:1305605
See related
Ensembl:ENSRNOG00000012147 AllianceGenome:RGD:1305605
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Rattus norvegicus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
Also known as
Nol14; RGD1305605
Summary
Predicted to enable enzyme binding activity. Predicted to be involved in maturation of SSU-rRNA. Predicted to be located in nucleoplasm. Predicted to be part of Noc4p-Nop14p complex and small-subunit processome. Predicted to be active in nucleolus. Orthologous to human NOP14 (NOP14 nucleolar protein). [provided by Alliance of Genome Resources, Apr 2022]
Expression
Biased expression in Spleen (RPKM 53.4), Thymus (RPKM 50.1) and 9 other tissues See more
Orthologs
human mouse all
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Genomic context

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Location:
14q21
Exon count:
18
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCr8 (GCF_036323735.1) 14 NC_086032.1 (80305912..80327053)
RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 14 NC_051349.1 (76081313..76102454)
106 previous assembly Rnor_6.0 (GCF_000001895.5) 14 NC_005113.4 (81340141..81361277)

Chromosome 14 - NC_086032.1Genomic Context describing neighboring genes Neighboring gene huntingtin Neighboring gene uncharacterized LOC134481857 Neighboring gene G protein-coupled receptor kinase 4 Neighboring gene major facilitator superfamily domain containing 10 Neighboring gene adducin 1 Neighboring gene uncharacterized LOC120096505 Neighboring gene SH3-domain binding protein 2

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
  • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
  • BioProject: PRJNA238328
  • Publication: PMID 24510058
  • Analysis date: Mon Jun 6 17:44:12 2016

Bibliography

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Related articles in PubMed

  1. A high-confidence interaction map identifies SIRT1 as a mediator of acetylation of USP22 and the SAGA coactivator complex. Armour SM, et al. Mol Cell Biol, 2013 Apr. PMID 23382074, Free PMC Article
  2. The mRNA-bound proteome and its global occupancy profile on protein-coding transcripts. Baltz AG, et al. Mol Cell, 2012 Jun 8. PMID 22681889
  3. Defining the membrane proteome of NK cells. Ghosh D, et al. J Mass Spectrom, 2010 Jan. PMID 19946888
  4. Insights into RNA biology from an atlas of mammalian mRNA-binding proteins. Castello A, et al. Cell, 2012 Jun 8. PMID 22658674
  5. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Markers

Homology

Gene Ontology Provided by RGD

Function Evidence Code Pubs
enables enzyme binding ISO
Inferred from Sequence Orthology
more info
  
Process Evidence Code Pubs
involved_in maturation of SSU-rRNA IBA
Inferred from Biological aspect of Ancestor
more info
  
Component Evidence Code Pubs
part_of Noc4p-Nop14p complex IBA
Inferred from Biological aspect of Ancestor
more info
  
is_active_in nucleolus IBA
Inferred from Biological aspect of Ancestor
more info
  
located_in nucleolus ISO
Inferred from Sequence Orthology
more info
  
located_in nucleoplasm IEA
Inferred from Electronic Annotation
more info
  
located_in nucleoplasm ISO
Inferred from Sequence Orthology
more info
  
part_of small-subunit processome IBA
Inferred from Biological aspect of Ancestor
more info
  

General protein information

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Preferred Names
nucleolar protein 14
Names
NOP14 nucleolar protein homolog

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001394594.1 → NP_001381523.1  nucleolar protein 14

    Status: VALIDATED

    Source sequence(s)
    JAXUCZ010000014
    UniProtKB/TrEMBL
    A0A0G2K0Z9, A6IK19
    Related
    ENSRNOP00000071645.1, ENSRNOT00000082612.2
    Conserved Domains (1) summary
    pfam04147
    Location:26 → 851
    Nop14; Nop14-like family

RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCr8

Genomic

  1. NC_086032.1 Reference GRCr8

    Range
    80305912..80327053
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

RNA

  1. XR_005492920.2 RNA Sequence

Suppressed Reference Sequence(s)

The following Reference Sequences have been suppressed. Explain

  1. NM_001106013.1: Suppressed sequence

    Description
    NM_001106013.1: This RefSeq was removed because it is a nonsense-mediated mRNA decay (NMD) candidate.
Nucleotide Protein Strain
Heading Accession and Version

Gene LinkOut

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