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tah18 putative NADPH-dependent diflavin oxidoreductase Tah18 [ Schizosaccharomyces pombe (fission yeast) ]

Gene ID: 2542966, updated on 13-Mar-2024

Summary

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Gene symbol
tah18
Gene description
putative NADPH-dependent diflavin oxidoreductase Tah18
Primary source
PomBase:SPAC1296.06
Locus tag
SPAC1296.06
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Schizosaccharomyces pombe (strain: 972h-)
Lineage
Eukaryota; Fungi; Dikarya; Ascomycota; Taphrinomycotina; Schizosaccharomycetes; Schizosaccharomycetales; Schizosaccharomycetaceae; Schizosaccharomyces
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Genomic context

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Location:
chromosome: I
Exon count:
5
Sequence:
Chromosome: I; NC_003424.3 (719380..721549)

Chromosome I - NC_003424.3Genomic Context describing neighboring genes Neighboring gene putative cyclin L family cyclin Neighboring gene putative spore wall assembly protein Neighboring gene tRNA-Glu Neighboring gene retromer complex subunit Vps17 Neighboring gene putative actin cortical patch component Lsb4 Neighboring gene putative Fe-responsive transcriptional regulator Neighboring gene putative karyopherin Kap111 Neighboring gene miscRNA

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_003424.3

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. A newly identified essential complex, Dre2-Tah18, controls mitochondria integrity and cell death after oxidative stress in yeast. Vernis L, et al. PLoS One, 2009. PMID 19194512, Free PMC Article
  2. The role of mitochondria and the CIA machinery in the maturation of cytosolic and nuclear iron-sulfur proteins. Lill R, et al. Eur J Cell Biol, 2015 Jul-Sep. PMID 26099175
  3. The genome sequence of Schizosaccharomyces pombe. Wood V, et al. Nature, 2002 Feb 21. PMID 11859360
  4. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by PomBase

Function Evidence Code Pubs
enables FMN binding IBA
Inferred from Biological aspect of Ancestor
more info
  
enables NADP binding ISS
Inferred from Sequence or Structural Similarity
more info
  
enables NADPH-hemoprotein reductase activity IEA
Inferred from Electronic Annotation
more info
  
enables flavin adenine dinucleotide binding IBA
Inferred from Biological aspect of Ancestor
more info
  
enables oxidoreductase activity IBA
Inferred from Biological aspect of Ancestor
more info
  
Process Evidence Code Pubs
involved_in [4Fe-4S] cluster assembly ISO
Inferred from Sequence Orthology
more info
 PubMed 
Component Evidence Code Pubs
is_active_in cytosol IBA
Inferred from Biological aspect of Ancestor
more info
  
is_active_in mitochondrion ISO
Inferred from Sequence Orthology
more info
 PubMed 

General protein information

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Preferred Names
putative NADPH-dependent diflavin oxidoreductase Tah18

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_003424.3 Reference assembly

    Range
    719380..721549
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001018445.2 → NP_593046.2  putative NADPH-dependent diflavin oxidoreductase Tah18 [Schizosaccharomyces pombe]

    See identical proteins and their annotated locations for NP_593046.2

    Status: PROVISIONAL

    UniProtKB/Swiss-Prot
    O94613
    Conserved Domains (3) summary
    COG0369
    Location:2 → 584
    CysJ; Sulfite reductase, alpha subunit (flavoprotein) [Inorganic ion transport and metabolism]
    pfam00258
    Location:8 → 145
    Flavodoxin_1; Flavodoxin
    cl06868
    Location:206 → 584
    FNR_like; Ferredoxin reductase (FNR), an FAD and NAD(P) binding protein, was intially identified as a chloroplast reductase activity, catalyzing the electron transfer from reduced iron-sulfur protein ferredoxin to NADP+ as the final step in the electron transport ...
Nucleotide Protein
Heading Accession and Version

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