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Ablim2 actin-binding LIM protein 2 [ Mus musculus (house mouse) ]

Gene ID: 231148, updated on 5-Mar-2024

Summary

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Official Symbol
Ablim2provided by MGI
Official Full Name
actin-binding LIM protein 2provided by MGI
Primary source
MGI:MGI:2385758
See related
Ensembl:ENSMUSG00000029095 AllianceGenome:MGI:2385758
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
C230091L11
Summary
Predicted to enable actin filament binding activity. Acts upstream of or within positive regulation of transcription by RNA polymerase II. Located in myofibril. Is expressed in several structures, including brain; diaphragm; early conceptus; oocyte; and skeletal muscle. Orthologous to human ABLIM2 (actin binding LIM protein family member 2). [provided by Alliance of Genome Resources, Apr 2022]
Expression
Broad expression in cortex adult (RPKM 21.7), frontal lobe adult (RPKM 17.1) and 17 other tissues See more
Orthologs
human all
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Genomic context

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Location:
5 B3; 5 18.75 cM
Exon count:
26
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCm39 (GCF_000001635.27) 5 NC_000071.7 (35915200..36042323)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 5 NC_000071.6 (35757855..35884979)

Chromosome 5 - NC_000071.7Genomic Context describing neighboring genes Neighboring gene STARR-seq mESC enhancer starr_12860 Neighboring gene HtrA serine peptidase 3 Neighboring gene STARR-positive B cell enhancer ABC_E8820 Neighboring gene SH3 domain and tetratricopeptide repeats 1 Neighboring gene predicted gene, 31888 Neighboring gene STARR-positive B cell enhancer ABC_E8050 Neighboring gene H2A histone family, pseudogene 1 Neighboring gene actin filament associated protein 1 Neighboring gene CapStarr-seq enhancer MGSCv37_chr5:36316611-36316857 Neighboring gene STARR-positive B cell enhancer mm9_chr5:36376513-36376814 Neighboring gene sortilin-related VPS10 domain containing receptor 2 Neighboring gene CapStarr-seq enhancer MGSCv37_chr5:36431991-36432296 Neighboring gene predicted gene, 52811

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Bibliography

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Related articles in PubMed

  1. Genomic organisation and tissue specific expression of ABLIM2 gene in human, mouse and rat. Klimov E, et al. Biochim Biophys Acta, 2005 Jul 25. PMID 16005990
  2. Two novel members of the ABLIM protein family, ABLIM-2 and -3, associate with STARS and directly bind F-actin. Barrientos T, et al. J Biol Chem, 2007 Mar 16. PMID 17194709
  3. Vti1b promotes TRPV1 sensitization during inflammatory pain. Sondermann JR, et al. Pain, 2019 Feb. PMID 30335684
  4. Interactome Analysis Reveals Regulator of G Protein Signaling 14 (RGS14) is a Novel Calcium/Calmodulin (Ca(2+)/CaM) and CaM Kinase II (CaMKII) Binding Partner. Evans PR, et al. J Proteome Res, 2018 Apr 6. PMID 29518331, Free PMC Article
  5. Comprehensive identification of phosphorylation sites in postsynaptic density preparations. Trinidad JC, et al. Mol Cell Proteomics, 2006 May. PMID 16452087

See all (23) citations in PubMed

GeneRIFs: Gene References Into Functions

What's a GeneRIF?
  1. ABLIM-2 and -3 associate with STARS and directly bind F-actin
    Title: Two novel members of the ABLIM protein family, ABLIM-2 and -3, associate with STARS and directly bind F-actin.
  2. The highest expression of both isoforms was observed in rat brain and eye and in mouse embryos. ABLIM2 protein was necessary for the normal functioning of neurons.
    Title: Genomic organisation and tissue specific expression of ABLIM2 gene in human, mouse and rat.
Submit: New GeneRIF Correction

Variation

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Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)
  • Endonuclease-mediated (2) 

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Markers

Homology

Gene Ontology Provided by MGI

Function Evidence Code Pubs
enables actin binding IEA
Inferred from Electronic Annotation
more info
  
enables actin filament binding IBA
Inferred from Biological aspect of Ancestor
more info
  
enables metal ion binding IEA
Inferred from Electronic Annotation
more info
  
Process Evidence Code Pubs
involved_in cytoskeleton organization IEA
Inferred from Electronic Annotation
more info
  
involved_in lamellipodium assembly IBA
Inferred from Biological aspect of Ancestor
more info
  
acts_upstream_of_or_within positive regulation of transcription by RNA polymerase II IMP
Inferred from Mutant Phenotype
more info
 PubMed 
acts_upstream_of transcription by RNA polymerase II IMP
Inferred from Mutant Phenotype
more info
 PubMed 
Component Evidence Code Pubs
is_active_in actin cytoskeleton IBA
Inferred from Biological aspect of Ancestor
more info
  
located_in actin cytoskeleton ISO
Inferred from Sequence Orthology
more info
 PubMed 
located_in cytoplasm IEA
Inferred from Electronic Annotation
more info
  
located_in myofibril IDA
Inferred from Direct Assay
more info
 PubMed 

General protein information

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Preferred Names
actin-binding LIM protein 2
Names
abLIM-2
actin-binding LIM protein family member 2

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001177696.1 → NP_001171167.1  actin-binding LIM protein 2 isoform 1

    Status: VALIDATED

    Description
    Transcript Variant: This variant (1) represents the longest transcript and encodes the longest isoform (1).
    Source sequence(s)
    AC141898
    Consensus CDS
    CCDS51473.1
    UniProtKB/TrEMBL
    E9Q4K0, Q19VH2
    Related
    ENSMUSP00000123525.2, ENSMUST00000129347.8
    Conserved Domains (6) summary
    cd09327
    Location:24 → 75
    LIM1_abLIM; The first LIM domain of actin binding LIM (abLIM) proteins
    cd09328
    Location:80 → 135
    LIM2_abLIM; The second LIM domain on actin binding LIM (abLIM) proteins
    cd09329
    Location:153 → 204
    LIM3_abLIM; The third LIM domain of actin binding LIM (abLIM) proteins
    cd09330
    Location:212 → 267
    LIM4_abLIM; The fourth LIM domain of actin binding LIM (abLIM) proteins
    pfam02209
    Location:630 → 664
    VHP; Villin headpiece domain
    pfam16182
    Location:296 → 628
    AbLIM_anchor; Putative adherens-junction anchoring region of AbLIM

  2. NM_001177697.1 → NP_001171168.1  actin-binding LIM protein 2 isoform 2

    Status: VALIDATED

    Description
    Transcript Variant: This variant (2) lacks three alternate exons and includes an alternate exon, compared to variant 1. The resulting isoform (2) lacks two internal segments and includes an additional internal segment, compared to isoform 1.
    Source sequence(s)
    AC141898, AK046243, AK046879
    Consensus CDS
    CCDS51475.1
    UniProtKB/TrEMBL
    Q3U409
    Related
    ENSMUSP00000109844.3, ENSMUST00000114206.9
    Conserved Domains (6) summary
    cd09327
    Location:24 → 75
    LIM1_abLIM; The first LIM domain of actin binding LIM (abLIM) proteins
    cd09328
    Location:80 → 135
    LIM2_abLIM; The second LIM domain on actin binding LIM (abLIM) proteins
    cd09329
    Location:153 → 204
    LIM3_abLIM; The third LIM domain of actin binding LIM (abLIM) proteins
    cd09330
    Location:212 → 267
    LIM4_abLIM; The fourth LIM domain of actin binding LIM (abLIM) proteins
    pfam02209
    Location:583 → 617
    VHP; Villin headpiece domain
    pfam16182
    Location:277 → 581
    AbLIM_anchor; Putative adherens-junction anchoring region of AbLIM

  3. NM_001177698.1 → NP_001171169.1  actin-binding LIM protein 2 isoform 4

    Status: VALIDATED

    Description
    Transcript Variant: This variant (4) lacks three alternate exons, compared to variant 1. The resulting isoform (4) lacks two internal segments, compared to isoform 1.
    Source sequence(s)
    AC141898
    Consensus CDS
    CCDS51474.1
    UniProtKB/TrEMBL
    E9Q0W6, Q3U409
    Related
    ENSMUSP00000098838.4, ENSMUST00000101280.10
    Conserved Domains (6) summary
    cd09327
    Location:24 → 75
    LIM1_abLIM; The first LIM domain of actin binding LIM (abLIM) proteins
    cd09328
    Location:80 → 135
    LIM2_abLIM; The second LIM domain on actin binding LIM (abLIM) proteins
    cd09329
    Location:153 → 204
    LIM3_abLIM; The third LIM domain of actin binding LIM (abLIM) proteins
    cd09330
    Location:212 → 267
    LIM4_abLIM; The fourth LIM domain of actin binding LIM (abLIM) proteins
    pfam02209
    Location:573 → 607
    VHP; Villin headpiece domain
    pfam16182
    Location:296 → 571
    AbLIM_anchor; Putative adherens-junction anchoring region of AbLIM

  4. NM_001177699.1 → NP_001171170.1  actin-binding LIM protein 2 isoform 5

    See identical proteins and their annotated locations for NP_001171170.1

    Status: VALIDATED

    Description
    Transcript Variant: This variant (5) lacks three alternate exons, compared to variant 1. The resulting isoform (5) lacks two internal segments, compared to isoform 1.
    Source sequence(s)
    AC141898, AY274116
    Consensus CDS
    CCDS51476.1
    UniProtKB/TrEMBL
    Q3U409
    Related
    ENSMUSP00000109842.2, ENSMUST00000114204.8
    Conserved Domains (6) summary
    cd09327
    Location:24 → 75
    LIM1_abLIM; The first LIM domain of actin binding LIM (abLIM) proteins
    cd09328
    Location:80 → 135
    LIM2_abLIM; The second LIM domain on actin binding LIM (abLIM) proteins
    cd09329
    Location:153 → 204
    LIM3_abLIM; The third LIM domain of actin binding LIM (abLIM) proteins
    cd09330
    Location:212 → 267
    LIM4_abLIM; The fourth LIM domain of actin binding LIM (abLIM) proteins
    pfam02209
    Location:572 → 606
    VHP; Villin headpiece domain
    pfam16182
    Location:277 → 570
    AbLIM_anchor; Putative adherens-junction anchoring region of AbLIM

  5. NM_001177700.1 → NP_001171171.1  actin-binding LIM protein 2 isoform 6

    See identical proteins and their annotated locations for NP_001171171.1

    Status: VALIDATED

    Description
    Transcript Variant: This variant (6) lacks four alternate exons, compared to variant 1. The resulting isoform (6) lacks three internal segments, compared to isoform 1.
    Source sequence(s)
    AC141898
    Consensus CDS
    CCDS51477.1
    UniProtKB/TrEMBL
    Q3U409
    Related
    ENSMUSP00000109843.2, ENSMUST00000114205.8
    Conserved Domains (6) summary
    cd09327
    Location:24 → 75
    LIM1_abLIM; The first LIM domain of actin binding LIM (abLIM) proteins
    cd09328
    Location:80 → 135
    LIM2_abLIM; The second LIM domain on actin binding LIM (abLIM) proteins
    cd09329
    Location:153 → 204
    LIM3_abLIM; The third LIM domain of actin binding LIM (abLIM) proteins
    cd09330
    Location:212 → 267
    LIM4_abLIM; The fourth LIM domain of actin binding LIM (abLIM) proteins
    pfam02209
    Location:539 → 573
    VHP; Villin headpiece domain
    pfam16182
    Location:277 → 537
    AbLIM_anchor; Putative adherens-junction anchoring region of AbLIM

  6. NM_177678.7 → NP_808346.3  actin-binding LIM protein 2 isoform 3

    See identical proteins and their annotated locations for NP_808346.3

    Status: VALIDATED

    Description
    Transcript Variant: This variant (3) lacks two alternate exons, compared to variant 1. The resulting isoform (3) lacks two internal segments, compared to isoform 1.
    Source sequence(s)
    AC141898, AK046243, AK046879
    Consensus CDS
    CCDS19235.1
    UniProtKB/Swiss-Prot
    B2RUF8, Q6H8P8, Q80WK6, Q8BL65, Q8BUT1, Q8BXI7
    UniProtKB/TrEMBL
    Q19VH2
    Related
    ENSMUSP00000050571.6, ENSMUST00000054598.12
    Conserved Domains (6) summary
    cd09327
    Location:24 → 75
    LIM1_abLIM; The first LIM domain of actin binding LIM (abLIM) proteins
    cd09328
    Location:80 → 135
    LIM2_abLIM; The second LIM domain on actin binding LIM (abLIM) proteins
    cd09329
    Location:153 → 204
    LIM3_abLIM; The third LIM domain of actin binding LIM (abLIM) proteins
    cd09330
    Location:212 → 267
    LIM4_abLIM; The fourth LIM domain of actin binding LIM (abLIM) proteins
    pfam02209
    Location:578 → 612
    VHP; Villin headpiece domain
    pfam16182
    Location:277 → 576
    AbLIM_anchor; Putative adherens-junction anchoring region of AbLIM

RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000071.7 Reference GRCm39 C57BL/6J

    Range
    35915200..36042323
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_006503906.2 → XP_006503969.1  actin-binding LIM protein 2 isoform X2

    UniProtKB/TrEMBL
    Q19VH2
    Conserved Domains (6) summary
    cd09327
    Location:24 → 75
    LIM1_abLIM; The first LIM domain of actin binding LIM (abLIM) proteins
    cd09328
    Location:80 → 135
    LIM2_abLIM; The second LIM domain on actin binding LIM (abLIM) proteins
    cd09329
    Location:153 → 204
    LIM3_abLIM; The third LIM domain of actin binding LIM (abLIM) proteins
    cd09330
    Location:212 → 267
    LIM4_abLIM; The fourth LIM domain of actin binding LIM (abLIM) proteins
    pfam02209
    Location:680 → 714
    VHP; Villin headpiece domain
    pfam16182
    Location:295 → 678
    AbLIM_anchor; Putative adherens-junction anchoring region of AbLIM

  2. XM_006503912.2 → XP_006503975.1  actin-binding LIM protein 2 isoform X13

    UniProtKB/TrEMBL
    Q19VH2
    Conserved Domains (6) summary
    cd09327
    Location:24 → 75
    LIM1_abLIM; The first LIM domain of actin binding LIM (abLIM) proteins
    cd09328
    Location:80 → 135
    LIM2_abLIM; The second LIM domain on actin binding LIM (abLIM) proteins
    cd09329
    Location:153 → 204
    LIM3_abLIM; The third LIM domain of actin binding LIM (abLIM) proteins
    cd09330
    Location:212 → 267
    LIM4_abLIM; The fourth LIM domain of actin binding LIM (abLIM) proteins
    pfam02209
    Location:640 → 674
    VHP; Villin headpiece domain
    pfam16182
    Location:295 → 638
    AbLIM_anchor; Putative adherens-junction anchoring region of AbLIM

  3. XM_030254381.2 → XP_030110241.1  actin-binding LIM protein 2 isoform X22

    UniProtKB/TrEMBL
    Q19VH2
    Conserved Domains (6) summary
    cd09327
    Location:24 → 75
    LIM1_abLIM; The first LIM domain of actin binding LIM (abLIM) proteins
    cd09328
    Location:80 → 135
    LIM2_abLIM; The second LIM domain on actin binding LIM (abLIM) proteins
    cd09329
    Location:153 → 204
    LIM3_abLIM; The third LIM domain of actin binding LIM (abLIM) proteins
    cd09330
    Location:212 → 267
    LIM4_abLIM; The fourth LIM domain of actin binding LIM (abLIM) proteins
    pfam02209
    Location:607 → 641
    VHP; Villin headpiece domain
    pfam16182
    Location:295 → 605
    AbLIM_anchor; Putative adherens-junction anchoring region of AbLIM

  4. XM_006503907.2 → XP_006503970.1  actin-binding LIM protein 2 isoform X4

    UniProtKB/TrEMBL
    Q19VH2
    Conserved Domains (6) summary
    cd09327
    Location:24 → 75
    LIM1_abLIM; The first LIM domain of actin binding LIM (abLIM) proteins
    cd09328
    Location:80 → 135
    LIM2_abLIM; The second LIM domain on actin binding LIM (abLIM) proteins
    cd09329
    Location:153 → 204
    LIM3_abLIM; The third LIM domain of actin binding LIM (abLIM) proteins
    cd09330
    Location:212 → 267
    LIM4_abLIM; The fourth LIM domain of actin binding LIM (abLIM) proteins
    pfam02209
    Location:669 → 703
    VHP; Villin headpiece domain
    pfam16182
    Location:295 → 667
    AbLIM_anchor; Putative adherens-junction anchoring region of AbLIM

  5. XM_006503908.2 → XP_006503971.1  actin-binding LIM protein 2 isoform X6

    UniProtKB/TrEMBL
    Q19VH2
    Conserved Domains (6) summary
    cd09327
    Location:24 → 75
    LIM1_abLIM; The first LIM domain of actin binding LIM (abLIM) proteins
    cd09328
    Location:80 → 135
    LIM2_abLIM; The second LIM domain on actin binding LIM (abLIM) proteins
    cd09329
    Location:153 → 204
    LIM3_abLIM; The third LIM domain of actin binding LIM (abLIM) proteins
    cd09330
    Location:212 → 267
    LIM4_abLIM; The fourth LIM domain of actin binding LIM (abLIM) proteins
    pfam02209
    Location:661 → 695
    VHP; Villin headpiece domain
    pfam16182
    Location:276 → 659
    AbLIM_anchor; Putative adherens-junction anchoring region of AbLIM

  6. XM_036165035.1 → XP_036020928.1  actin-binding LIM protein 2 isoform X18

    UniProtKB/TrEMBL
    Q19VH2
    Conserved Domains (6) summary
    cd09327
    Location:24 → 75
    LIM1_abLIM; The first LIM domain of actin binding LIM (abLIM) proteins
    cd09328
    Location:80 → 135
    LIM2_abLIM; The second LIM domain on actin binding LIM (abLIM) proteins
    cd09329
    Location:153 → 204
    LIM3_abLIM; The third LIM domain of actin binding LIM (abLIM) proteins
    cd09330
    Location:212 → 267
    LIM4_abLIM; The fourth LIM domain of actin binding LIM (abLIM) proteins
    pfam02209
    Location:621 → 655
    VHP; Villin headpiece domain
    pfam16182
    Location:276 → 620
    AbLIM_anchor; Putative adherens-junction anchoring region of AbLIM

  7. XM_036165042.1 → XP_036020935.1  actin-binding LIM protein 2 isoform X28

    UniProtKB/TrEMBL
    Q19VH2
    Conserved Domains (6) summary
    cd09327
    Location:24 → 75
    LIM1_abLIM; The first LIM domain of actin binding LIM (abLIM) proteins
    cd09328
    Location:80 → 135
    LIM2_abLIM; The second LIM domain on actin binding LIM (abLIM) proteins
    cd09329
    Location:153 → 204
    LIM3_abLIM; The third LIM domain of actin binding LIM (abLIM) proteins
    cd09330
    Location:212 → 267
    LIM4_abLIM; The fourth LIM domain of actin binding LIM (abLIM) proteins
    pfam02209
    Location:588 → 622
    VHP; Villin headpiece domain
    pfam16182
    Location:276 → 587
    AbLIM_anchor; Putative adherens-junction anchoring region of AbLIM

  8. XM_006503909.2 → XP_006503972.1  actin-binding LIM protein 2 isoform X9

    UniProtKB/TrEMBL
    Q19VH2
    Conserved Domains (6) summary
    cd09327
    Location:24 → 75
    LIM1_abLIM; The first LIM domain of actin binding LIM (abLIM) proteins
    cd09328
    Location:80 → 135
    LIM2_abLIM; The second LIM domain on actin binding LIM (abLIM) proteins
    cd09329
    Location:153 → 204
    LIM3_abLIM; The third LIM domain of actin binding LIM (abLIM) proteins
    cd09330
    Location:212 → 267
    LIM4_abLIM; The fourth LIM domain of actin binding LIM (abLIM) proteins
    pfam02209
    Location:650 → 684
    VHP; Villin headpiece domain
    pfam16182
    Location:276 → 648
    AbLIM_anchor; Putative adherens-junction anchoring region of AbLIM

  9. XM_030254383.2 → XP_030110243.1  actin-binding LIM protein 2 isoform X32

    UniProtKB/TrEMBL
    Q19VH2
    Conserved Domains (6) summary
    cd09327
    Location:24 → 75
    LIM1_abLIM; The first LIM domain of actin binding LIM (abLIM) proteins
    cd09328
    Location:80 → 135
    LIM2_abLIM; The second LIM domain on actin binding LIM (abLIM) proteins
    cd09329
    Location:153 → 204
    LIM3_abLIM; The third LIM domain of actin binding LIM (abLIM) proteins
    cd09330
    Location:212 → 267
    LIM4_abLIM; The fourth LIM domain of actin binding LIM (abLIM) proteins
    pfam02209
    Location:559 → 593
    VHP; Villin headpiece domain
    pfam16182
    Location:276 → 557
    AbLIM_anchor; Putative adherens-junction anchoring region of AbLIM

  10. XM_006503922.2 → XP_006503985.1  actin-binding LIM protein 2 isoform X33

    UniProtKB/TrEMBL
    Q19VH2
    Conserved Domains (6) summary
    smart00153
    Location:525 → 560
    VHP; Villin headpiece domain
    cd09327
    Location:24 → 75
    LIM1_abLIM; The first LIM domain of actin binding LIM (abLIM) proteins
    cd09328
    Location:80 → 135
    LIM2_abLIM; The second LIM domain on actin binding LIM (abLIM) proteins
    cd09329
    Location:153 → 204
    LIM3_abLIM; The third LIM domain of actin binding LIM (abLIM) proteins
    cd09330
    Location:212 → 267
    LIM4_abLIM; The fourth LIM domain of actin binding LIM (abLIM) proteins
    pfam16182
    Location:276 → 523
    AbLIM_anchor; Putative adherens-junction anchoring region of AbLIM

  11. XM_006503916.2 → XP_006503979.1  actin-binding LIM protein 2 isoform X21

    UniProtKB/TrEMBL
    Q19VH2
    Related
    ENSMUSP00000109848.3, ENSMUST00000114210.9
    Conserved Domains (6) summary
    cd09327
    Location:24 → 75
    LIM1_abLIM; The first LIM domain of actin binding LIM (abLIM) proteins
    cd09328
    Location:80 → 135
    LIM2_abLIM; The second LIM domain on actin binding LIM (abLIM) proteins
    cd09329
    Location:153 → 204
    LIM3_abLIM; The third LIM domain of actin binding LIM (abLIM) proteins
    cd09330
    Location:212 → 267
    LIM4_abLIM; The fourth LIM domain of actin binding LIM (abLIM) proteins
    pfam02209
    Location:610 → 644
    VHP; Villin headpiece domain
    pfam16182
    Location:276 → 608
    AbLIM_anchor; Putative adherens-junction anchoring region of AbLIM

  12. XM_030254382.2 → XP_030110242.1  actin-binding LIM protein 2 isoform X27

    UniProtKB/TrEMBL
    Q19VH2
    Conserved Domains (6) summary
    cd09327
    Location:24 → 75
    LIM1_abLIM; The first LIM domain of actin binding LIM (abLIM) proteins
    cd09328
    Location:80 → 135
    LIM2_abLIM; The second LIM domain on actin binding LIM (abLIM) proteins
    cd09329
    Location:153 → 204
    LIM3_abLIM; The third LIM domain of actin binding LIM (abLIM) proteins
    cd09330
    Location:212 → 267
    LIM4_abLIM; The fourth LIM domain of actin binding LIM (abLIM) proteins
    pfam02209
    Location:592 → 626
    VHP; Villin headpiece domain
    pfam16182
    Location:276 → 590
    AbLIM_anchor; Putative adherens-junction anchoring region of AbLIM

  13. XM_036165027.1 → XP_036020920.1  actin-binding LIM protein 2 isoform X8

    UniProtKB/TrEMBL
    Q19VH2
    Conserved Domains (6) summary
    cd09327
    Location:29 → 80
    LIM1_abLIM; The first LIM domain of actin binding LIM (abLIM) proteins
    cd09328
    Location:85 → 140
    LIM2_abLIM; The second LIM domain on actin binding LIM (abLIM) proteins
    cd09329
    Location:158 → 209
    LIM3_abLIM; The third LIM domain of actin binding LIM (abLIM) proteins
    cd09330
    Location:217 → 272
    LIM4_abLIM; The fourth LIM domain of actin binding LIM (abLIM) proteins
    pfam02209
    Location:652 → 686
    VHP; Villin headpiece domain
    pfam16182
    Location:300 → 651
    AbLIM_anchor; Putative adherens-junction anchoring region of AbLIM

  14. XM_036165033.1 → XP_036020926.1  actin-binding LIM protein 2 isoform X16

    UniProtKB/TrEMBL
    Q19VH2
    Conserved Domains (5) summary
    cd09327
    Location:29 → 80
    LIM1_abLIM; The first LIM domain of actin binding LIM (abLIM) proteins
    cd09328
    Location:85 → 140
    LIM2_abLIM; The second LIM domain on actin binding LIM (abLIM) proteins
    cd09329
    Location:158 → 209
    LIM3_abLIM; The third LIM domain of actin binding LIM (abLIM) proteins
    cd09330
    Location:217 → 272
    LIM4_abLIM; The fourth LIM domain of actin binding LIM (abLIM) proteins
    pfam16182
    Location:300 → 657
    AbLIM_anchor; Putative adherens-junction anchoring region of AbLIM

  15. XM_036165039.1 → XP_036020932.1  actin-binding LIM protein 2 isoform X24

    UniProtKB/TrEMBL
    Q19VH2
    Conserved Domains (5) summary
    cd09327
    Location:29 → 80
    LIM1_abLIM; The first LIM domain of actin binding LIM (abLIM) proteins
    cd09328
    Location:85 → 140
    LIM2_abLIM; The second LIM domain on actin binding LIM (abLIM) proteins
    cd09329
    Location:158 → 209
    LIM3_abLIM; The third LIM domain of actin binding LIM (abLIM) proteins
    cd09330
    Location:217 → 272
    LIM4_abLIM; The fourth LIM domain of actin binding LIM (abLIM) proteins
    pfam16182
    Location:300 → 632
    AbLIM_anchor; Putative adherens-junction anchoring region of AbLIM

  16. XM_036165043.1 → XP_036020936.1  actin-binding LIM protein 2 isoform X29

    UniProtKB/TrEMBL
    Q3U409
    Conserved Domains (5) summary
    cd09327
    Location:29 → 80
    LIM1_abLIM; The first LIM domain of actin binding LIM (abLIM) proteins
    cd09328
    Location:85 → 140
    LIM2_abLIM; The second LIM domain on actin binding LIM (abLIM) proteins
    cd09329
    Location:158 → 209
    LIM3_abLIM; The third LIM domain of actin binding LIM (abLIM) proteins
    cd09330
    Location:217 → 272
    LIM4_abLIM; The fourth LIM domain of actin binding LIM (abLIM) proteins
    pfam16182
    Location:300 → 586
    AbLIM_anchor; Putative adherens-junction anchoring region of AbLIM

  17. XM_036165023.1 → XP_036020916.1  actin-binding LIM protein 2 isoform X1

    UniProtKB/TrEMBL
    Q19VH2
    Conserved Domains (6) summary
    cd09327
    Location:29 → 80
    LIM1_abLIM; The first LIM domain of actin binding LIM (abLIM) proteins
    cd09328
    Location:85 → 140
    LIM2_abLIM; The second LIM domain on actin binding LIM (abLIM) proteins
    cd09329
    Location:158 → 209
    LIM3_abLIM; The third LIM domain of actin binding LIM (abLIM) proteins
    cd09330
    Location:217 → 272
    LIM4_abLIM; The fourth LIM domain of actin binding LIM (abLIM) proteins
    pfam02209
    Location:685 → 719
    VHP; Villin headpiece domain
    pfam16182
    Location:300 → 684
    AbLIM_anchor; Putative adherens-junction anchoring region of AbLIM

  18. XM_036165030.1 → XP_036020923.1  actin-binding LIM protein 2 isoform X12

    UniProtKB/TrEMBL
    Q19VH2
    Conserved Domains (6) summary
    cd09327
    Location:29 → 80
    LIM1_abLIM; The first LIM domain of actin binding LIM (abLIM) proteins
    cd09328
    Location:85 → 140
    LIM2_abLIM; The second LIM domain on actin binding LIM (abLIM) proteins
    cd09329
    Location:158 → 209
    LIM3_abLIM; The third LIM domain of actin binding LIM (abLIM) proteins
    cd09330
    Location:217 → 272
    LIM4_abLIM; The fourth LIM domain of actin binding LIM (abLIM) proteins
    pfam02209
    Location:641 → 675
    VHP; Villin headpiece domain
    pfam16182
    Location:300 → 640
    AbLIM_anchor; Putative adherens-junction anchoring region of AbLIM

  19. XM_036165037.1 → XP_036020930.1  actin-binding LIM protein 2 isoform X20

    UniProtKB/TrEMBL
    Q19VH2
    Conserved Domains (6) summary
    cd09327
    Location:29 → 80
    LIM1_abLIM; The first LIM domain of actin binding LIM (abLIM) proteins
    cd09328
    Location:85 → 140
    LIM2_abLIM; The second LIM domain on actin binding LIM (abLIM) proteins
    cd09329
    Location:158 → 209
    LIM3_abLIM; The third LIM domain of actin binding LIM (abLIM) proteins
    cd09330
    Location:217 → 272
    LIM4_abLIM; The fourth LIM domain of actin binding LIM (abLIM) proteins
    pfam02209
    Location:612 → 646
    VHP; Villin headpiece domain
    pfam16182
    Location:300 → 611
    AbLIM_anchor; Putative adherens-junction anchoring region of AbLIM

  20. XM_036165034.1 → XP_036020927.1  actin-binding LIM protein 2 isoform X17

    UniProtKB/TrEMBL
    Q19VH2
    Conserved Domains (6) summary
    cd09327
    Location:29 → 80
    LIM1_abLIM; The first LIM domain of actin binding LIM (abLIM) proteins
    cd09328
    Location:85 → 140
    LIM2_abLIM; The second LIM domain on actin binding LIM (abLIM) proteins
    cd09329
    Location:158 → 209
    LIM3_abLIM; The third LIM domain of actin binding LIM (abLIM) proteins
    cd09330
    Location:217 → 272
    LIM4_abLIM; The fourth LIM domain of actin binding LIM (abLIM) proteins
    pfam02209
    Location:622 → 656
    VHP; Villin headpiece domain
    pfam16182
    Location:281 → 621
    AbLIM_anchor; Putative adherens-junction anchoring region of AbLIM

  21. XM_036165025.1 → XP_036020918.1  actin-binding LIM protein 2 isoform X5

    UniProtKB/TrEMBL
    Q19VH2
    Conserved Domains (6) summary
    cd09327
    Location:29 → 80
    LIM1_abLIM; The first LIM domain of actin binding LIM (abLIM) proteins
    cd09328
    Location:85 → 140
    LIM2_abLIM; The second LIM domain on actin binding LIM (abLIM) proteins
    cd09329
    Location:158 → 209
    LIM3_abLIM; The third LIM domain of actin binding LIM (abLIM) proteins
    cd09330
    Location:217 → 272
    LIM4_abLIM; The fourth LIM domain of actin binding LIM (abLIM) proteins
    pfam02209
    Location:666 → 700
    VHP; Villin headpiece domain
    pfam16182
    Location:281 → 665
    AbLIM_anchor; Putative adherens-junction anchoring region of AbLIM

  22. XM_036165028.1 → XP_036020921.1  actin-binding LIM protein 2 isoform X10

    UniProtKB/TrEMBL
    Q3U409
    Conserved Domains (6) summary
    cd09327
    Location:29 → 80
    LIM1_abLIM; The first LIM domain of actin binding LIM (abLIM) proteins
    cd09328
    Location:85 → 140
    LIM2_abLIM; The second LIM domain on actin binding LIM (abLIM) proteins
    cd09329
    Location:158 → 209
    LIM3_abLIM; The third LIM domain of actin binding LIM (abLIM) proteins
    cd09330
    Location:217 → 272
    LIM4_abLIM; The fourth LIM domain of actin binding LIM (abLIM) proteins
    pfam02209
    Location:646 → 680
    VHP; Villin headpiece domain
    pfam16182
    Location:300 → 645
    AbLIM_anchor; Putative adherens-junction anchoring region of AbLIM

  23. XM_036165032.1 → XP_036020925.1  actin-binding LIM protein 2 isoform X15

    UniProtKB/TrEMBL
    Q19VH2
    Conserved Domains (6) summary
    cd09327
    Location:29 → 80
    LIM1_abLIM; The first LIM domain of actin binding LIM (abLIM) proteins
    cd09328
    Location:85 → 140
    LIM2_abLIM; The second LIM domain on actin binding LIM (abLIM) proteins
    cd09329
    Location:158 → 209
    LIM3_abLIM; The third LIM domain of actin binding LIM (abLIM) proteins
    cd09330
    Location:217 → 272
    LIM4_abLIM; The fourth LIM domain of actin binding LIM (abLIM) proteins
    pfam02209
    Location:627 → 661
    VHP; Villin headpiece domain
    pfam16182
    Location:300 → 626
    AbLIM_anchor; Putative adherens-junction anchoring region of AbLIM

  24. XM_036165024.1 → XP_036020917.1  actin-binding LIM protein 2 isoform X3

    UniProtKB/TrEMBL
    Q19VH2
    Conserved Domains (6) summary
    cd09327
    Location:29 → 80
    LIM1_abLIM; The first LIM domain of actin binding LIM (abLIM) proteins
    cd09328
    Location:85 → 140
    LIM2_abLIM; The second LIM domain on actin binding LIM (abLIM) proteins
    cd09329
    Location:158 → 209
    LIM3_abLIM; The third LIM domain of actin binding LIM (abLIM) proteins
    cd09330
    Location:217 → 272
    LIM4_abLIM; The fourth LIM domain of actin binding LIM (abLIM) proteins
    pfam02209
    Location:674 → 708
    VHP; Villin headpiece domain
    pfam16182
    Location:300 → 673
    AbLIM_anchor; Putative adherens-junction anchoring region of AbLIM

  25. XM_036165041.1 → XP_036020934.1  actin-binding LIM protein 2 isoform X26

    UniProtKB/TrEMBL
    Q19VH2
    Conserved Domains (6) summary
    cd09327
    Location:29 → 80
    LIM1_abLIM; The first LIM domain of actin binding LIM (abLIM) proteins
    cd09328
    Location:85 → 140
    LIM2_abLIM; The second LIM domain on actin binding LIM (abLIM) proteins
    cd09329
    Location:158 → 209
    LIM3_abLIM; The third LIM domain of actin binding LIM (abLIM) proteins
    cd09330
    Location:217 → 272
    LIM4_abLIM; The fourth LIM domain of actin binding LIM (abLIM) proteins
    pfam02209
    Location:593 → 627
    VHP; Villin headpiece domain
    pfam16182
    Location:281 → 592
    AbLIM_anchor; Putative adherens-junction anchoring region of AbLIM

  26. XM_036165029.1 → XP_036020922.1  actin-binding LIM protein 2 isoform X11

    UniProtKB/TrEMBL
    Q19VH2
    Conserved Domains (6) summary
    cd09327
    Location:29 → 80
    LIM1_abLIM; The first LIM domain of actin binding LIM (abLIM) proteins
    cd09328
    Location:85 → 140
    LIM2_abLIM; The second LIM domain on actin binding LIM (abLIM) proteins
    cd09329
    Location:158 → 209
    LIM3_abLIM; The third LIM domain of actin binding LIM (abLIM) proteins
    cd09330
    Location:217 → 272
    LIM4_abLIM; The fourth LIM domain of actin binding LIM (abLIM) proteins
    pfam02209
    Location:645 → 679
    VHP; Villin headpiece domain
    pfam16182
    Location:300 → 644
    AbLIM_anchor; Putative adherens-junction anchoring region of AbLIM

  27. XM_036165040.1 → XP_036020933.1  actin-binding LIM protein 2 isoform X25

    UniProtKB/TrEMBL
    Q19VH2
    Conserved Domains (6) summary
    cd09327
    Location:29 → 80
    LIM1_abLIM; The first LIM domain of actin binding LIM (abLIM) proteins
    cd09328
    Location:85 → 140
    LIM2_abLIM; The second LIM domain on actin binding LIM (abLIM) proteins
    cd09329
    Location:158 → 209
    LIM3_abLIM; The third LIM domain of actin binding LIM (abLIM) proteins
    cd09330
    Location:217 → 272
    LIM4_abLIM; The fourth LIM domain of actin binding LIM (abLIM) proteins
    pfam02209
    Location:601 → 635
    VHP; Villin headpiece domain
    pfam16182
    Location:300 → 600
    AbLIM_anchor; Putative adherens-junction anchoring region of AbLIM

  28. XM_036165026.1 → XP_036020919.1  actin-binding LIM protein 2 isoform X7

    UniProtKB/TrEMBL
    Q19VH2
    Conserved Domains (6) summary
    cd09327
    Location:29 → 80
    LIM1_abLIM; The first LIM domain of actin binding LIM (abLIM) proteins
    cd09328
    Location:85 → 140
    LIM2_abLIM; The second LIM domain on actin binding LIM (abLIM) proteins
    cd09329
    Location:158 → 209
    LIM3_abLIM; The third LIM domain of actin binding LIM (abLIM) proteins
    cd09330
    Location:217 → 272
    LIM4_abLIM; The fourth LIM domain of actin binding LIM (abLIM) proteins
    pfam02209
    Location:655 → 689
    VHP; Villin headpiece domain
    pfam16182
    Location:281 → 654
    AbLIM_anchor; Putative adherens-junction anchoring region of AbLIM

  29. XM_036165045.1 → XP_036020938.1  actin-binding LIM protein 2 isoform X31

    UniProtKB/TrEMBL
    Q19VH2
    Conserved Domains (6) summary
    cd09327
    Location:29 → 80
    LIM1_abLIM; The first LIM domain of actin binding LIM (abLIM) proteins
    cd09328
    Location:85 → 140
    LIM2_abLIM; The second LIM domain on actin binding LIM (abLIM) proteins
    cd09329
    Location:158 → 209
    LIM3_abLIM; The third LIM domain of actin binding LIM (abLIM) proteins
    cd09330
    Location:217 → 272
    LIM4_abLIM; The fourth LIM domain of actin binding LIM (abLIM) proteins
    pfam02209
    Location:582 → 616
    VHP; Villin headpiece domain
    pfam16182
    Location:281 → 581
    AbLIM_anchor; Putative adherens-junction anchoring region of AbLIM

  30. XM_036165031.1 → XP_036020924.1  actin-binding LIM protein 2 isoform X14

    UniProtKB/TrEMBL
    Q19VH2
    Conserved Domains (6) summary
    cd09327
    Location:29 → 80
    LIM1_abLIM; The first LIM domain of actin binding LIM (abLIM) proteins
    cd09328
    Location:85 → 140
    LIM2_abLIM; The second LIM domain on actin binding LIM (abLIM) proteins
    cd09329
    Location:158 → 209
    LIM3_abLIM; The third LIM domain of actin binding LIM (abLIM) proteins
    cd09330
    Location:217 → 272
    LIM4_abLIM; The fourth LIM domain of actin binding LIM (abLIM) proteins
    pfam02209
    Location:634 → 668
    VHP; Villin headpiece domain
    pfam16182
    Location:300 → 633
    AbLIM_anchor; Putative adherens-junction anchoring region of AbLIM

  31. XM_036165038.1 → XP_036020931.1  actin-binding LIM protein 2 isoform X23

    UniProtKB/TrEMBL
    Q3U409
    Conserved Domains (6) summary
    cd09327
    Location:29 → 80
    LIM1_abLIM; The first LIM domain of actin binding LIM (abLIM) proteins
    cd09328
    Location:85 → 140
    LIM2_abLIM; The second LIM domain on actin binding LIM (abLIM) proteins
    cd09329
    Location:158 → 209
    LIM3_abLIM; The third LIM domain of actin binding LIM (abLIM) proteins
    cd09330
    Location:217 → 272
    LIM4_abLIM; The fourth LIM domain of actin binding LIM (abLIM) proteins
    pfam02209
    Location:606 → 640
    VHP; Villin headpiece domain
    pfam16182
    Location:300 → 605
    AbLIM_anchor; Putative adherens-junction anchoring region of AbLIM

  32. XM_036165044.1 → XP_036020937.1  actin-binding LIM protein 2 isoform X30

    UniProtKB/TrEMBL
    Q3U409
    Conserved Domains (6) summary
    cd09327
    Location:29 → 80
    LIM1_abLIM; The first LIM domain of actin binding LIM (abLIM) proteins
    cd09328
    Location:85 → 140
    LIM2_abLIM; The second LIM domain on actin binding LIM (abLIM) proteins
    cd09329
    Location:158 → 209
    LIM3_abLIM; The third LIM domain of actin binding LIM (abLIM) proteins
    cd09330
    Location:217 → 272
    LIM4_abLIM; The fourth LIM domain of actin binding LIM (abLIM) proteins
    pfam02209
    Location:587 → 621
    VHP; Villin headpiece domain
    pfam16182
    Location:281 → 586
    AbLIM_anchor; Putative adherens-junction anchoring region of AbLIM

  33. XM_036165036.1 → XP_036020929.1  actin-binding LIM protein 2 isoform X19

    UniProtKB/TrEMBL
    Q19VH2
    Conserved Domains (6) summary
    cd09327
    Location:29 → 80
    LIM1_abLIM; The first LIM domain of actin binding LIM (abLIM) proteins
    cd09328
    Location:85 → 140
    LIM2_abLIM; The second LIM domain on actin binding LIM (abLIM) proteins
    cd09329
    Location:158 → 209
    LIM3_abLIM; The third LIM domain of actin binding LIM (abLIM) proteins
    cd09330
    Location:217 → 272
    LIM4_abLIM; The fourth LIM domain of actin binding LIM (abLIM) proteins
    pfam02209
    Location:615 → 649
    VHP; Villin headpiece domain
    pfam16182
    Location:281 → 614
    AbLIM_anchor; Putative adherens-junction anchoring region of AbLIM

  34. XM_006503925.4 → XP_006503988.1  actin-binding LIM protein 2 isoform X34

    Conserved Domains (3) summary
    cl02475
    Location:1 → 24
    LIM; LIM is a small protein-protein interaction domain, containing two zinc fingers
    pfam02209
    Location:437 → 471
    VHP; Villin headpiece domain
    pfam16182
    Location:52 → 435
    AbLIM_anchor; Putative adherens-junction anchoring region of AbLIM

  35. XM_036165049.1 → XP_036020942.1  actin-binding LIM protein 2 isoform X40

    UniProtKB/TrEMBL
    D3Z0Y4
    Conserved Domains (3) summary
    pfam02209
    Location:364 → 398
    VHP; Villin headpiece domain
    pfam16182
    Location:52 → 363
    AbLIM_anchor; Putative adherens-junction anchoring region of AbLIM
    cl02475
    Location:1 → 24
    LIM; LIM is a small protein-protein interaction domain, containing two zinc fingers

  36. XM_006503926.4 → XP_006503989.1  actin-binding LIM protein 2 isoform X35

    Conserved Domains (3) summary
    smart00153
    Location:418 → 453
    VHP; Villin headpiece domain
    cl02475
    Location:1 → 24
    LIM; LIM is a small protein-protein interaction domain, containing two zinc fingers
    pfam16182
    Location:33 → 416
    AbLIM_anchor; Putative adherens-junction anchoring region of AbLIM

  37. XM_036165051.1 → XP_036020944.1  actin-binding LIM protein 2 isoform X42

    UniProtKB/TrEMBL
    D3Z0Y4
    Related
    ENSMUSP00000109841.2, ENSMUST00000114203.8
    Conserved Domains (3) summary
    smart00153
    Location:345 → 380
    VHP; Villin headpiece domain
    pfam16182
    Location:33 → 344
    AbLIM_anchor; Putative adherens-junction anchoring region of AbLIM
    cl02475
    Location:1 → 24
    LIM; LIM is a small protein-protein interaction domain, containing two zinc fingers

  38. XM_036165046.1 → XP_036020939.1  actin-binding LIM protein 2 isoform X36

    UniProtKB/TrEMBL
    D3Z0Y4
    Conserved Domains (3) summary
    pfam02209
    Location:397 → 431
    VHP; Villin headpiece domain
    pfam16182
    Location:52 → 396
    AbLIM_anchor; Putative adherens-junction anchoring region of AbLIM
    cl02475
    Location:1 → 24
    LIM; LIM is a small protein-protein interaction domain, containing two zinc fingers

  39. XM_036165048.1 → XP_036020941.1  actin-binding LIM protein 2 isoform X38

    UniProtKB/TrEMBL
    D3Z0Y4
    Conserved Domains (3) summary
    pfam02209
    Location:378 → 412
    VHP; Villin headpiece domain
    pfam16182
    Location:33 → 377
    AbLIM_anchor; Putative adherens-junction anchoring region of AbLIM
    cl02475
    Location:1 → 24
    LIM; LIM is a small protein-protein interaction domain, containing two zinc fingers

  40. XM_030254385.2 → XP_030110245.1  actin-binding LIM protein 2 isoform X43

    UniProtKB/TrEMBL
    D3Z0Y4
    Conserved Domains (3) summary
    smart00153
    Location:334 → 369
    VHP; Villin headpiece domain
    cl02475
    Location:1 → 24
    LIM; LIM is a small protein-protein interaction domain, containing two zinc fingers
    pfam16182
    Location:33 → 332
    AbLIM_anchor; Putative adherens-junction anchoring region of AbLIM

  41. XM_036165047.1 → XP_036020940.1  actin-binding LIM protein 2 isoform X37

    Conserved Domains (3) summary
    pfam02209
    Location:386 → 420
    VHP; Villin headpiece domain
    pfam16182
    Location:52 → 385
    AbLIM_anchor; Putative adherens-junction anchoring region of AbLIM
    cl02475
    Location:1 → 24
    LIM; LIM is a small protein-protein interaction domain, containing two zinc fingers

  42. XM_036165050.1 → XP_036020943.1  actin-binding LIM protein 2 isoform X41

    UniProtKB/TrEMBL
    D3Z0Y4
    Conserved Domains (3) summary
    pfam02209
    Location:349 → 383
    VHP; Villin headpiece domain
    pfam16182
    Location:33 → 348
    AbLIM_anchor; Putative adherens-junction anchoring region of AbLIM
    cl02475
    Location:1 → 24
    LIM; LIM is a small protein-protein interaction domain, containing two zinc fingers

  43. XM_030254384.2 → XP_030110244.1  actin-binding LIM protein 2 isoform X39

    UniProtKB/TrEMBL
    D3Z0Y4
    Conserved Domains (3) summary
    smart00153
    Location:367 → 402
    VHP; Villin headpiece domain
    cl02475
    Location:1 → 24
    LIM; LIM is a small protein-protein interaction domain, containing two zinc fingers
    pfam16182
    Location:33 → 365
    AbLIM_anchor; Putative adherens-junction anchoring region of AbLIM

RNA

  1. XR_004942495.1 RNA Sequence

Nucleotide Protein Strain
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q8BL65.1 GenPept UniProtKB/Swiss-Prot:Q8BL65

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