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F57B9.1 Putative pyridoxamine 5'-phosphate oxidase [ Caenorhabditis elegans ]

Gene ID: 175973, updated on 23-Nov-2023

Summary

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Gene symbol
F57B9.1
Gene description
Putative pyridoxamine 5'-phosphate oxidase
Primary source
WormBase:WBGene00018996
Locus tag
CELE_F57B9.1
See related
AllianceGenome:WB:WBGene00018996
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Caenorhabditis elegans (strain: Bristol N2)
Lineage
Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
Summary
Predicted to enable pyridoxamine-phosphate oxidase activity. Predicted to be involved in pyridoxal phosphate biosynthetic process. Human ortholog(s) of this gene implicated in pyridoxamine 5'-phosphate oxidase deficiency. Orthologous to human PNPO (pyridoxamine 5'-phosphate oxidase). [provided by Alliance of Genome Resources, Apr 2022]
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Genomic context

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Location:
chromosome: III
Exon count:
4
Sequence:
Chromosome: III; NC_003281.10 (6962340..6963307)

Chromosome III - NC_003281.10Genomic Context describing neighboring genes Neighboring gene CCR4-NOT transcription complex subunit let-711 Neighboring gene putative 26S proteasome regulatory subunit rpn-6.1 Neighboring gene PAN (PolyA-specific riboNucLease) subunit Neighboring gene ncRNA Neighboring gene ncRNA

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_003281.10

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Systematic interactome mapping and genetic perturbation analysis of a C. elegans TGF-beta signaling network. Tewari M, et al. Mol Cell, 2004 Feb 27. PMID 14992718
  2. Interactome analysis of Caenorhabditis elegans synapses by TurboID-based proximity labeling. Artan M, et al. J Biol Chem, 2021 Sep. PMID 34416233, Free PMC Article
  3. Genome sequence of the nematode C. elegans: a platform for investigating biology. C. elegans Sequencing Consortium. Science, 1998 Dec 11. PMID 9851916
  4. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article

GeneRIFs: Gene References Into Functions

Pathways from PubChem

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Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Markers

Homology

Gene Ontology Provided by WormBase

Function Evidence Code Pubs
enables FMN binding IEA
Inferred from Electronic Annotation
more info
  
enables oxidoreductase activity IEA
Inferred from Electronic Annotation
more info
  
enables pyridoxamine phosphate oxidase activity IBA
Inferred from Biological aspect of Ancestor
more info
  
enables pyridoxamine phosphate oxidase activity IEA
Inferred from Electronic Annotation
more info
  
Process Evidence Code Pubs
involved_in cellular aromatic compound metabolic process IEA
Inferred from Electronic Annotation
more info
  
involved_in organic hydroxy compound metabolic process IEA
Inferred from Electronic Annotation
more info
  
involved_in pyridoxal phosphate biosynthetic process IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in pyridoxine biosynthetic process IEA
Inferred from Electronic Annotation
more info
  
involved_in vitamin B6 metabolic process IEA
Inferred from Electronic Annotation
more info
  

General protein information

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Preferred Names
Putative pyridoxamine 5'-phosphate oxidase
NP_001370689.1
  • Confirmed by transcript evidence

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_003281.10 Reference assembly

    Range
    6962340..6963307
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001382904.2 → NP_001370689.1  Putative pyridoxamine 5'-phosphate oxidase [Caenorhabditis elegans]

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    Q20939
    Conserved Domains (1) summary
    TIGR00558
    Location:32 → 226
    pdxH; pyridoxamine-phosphate oxidase
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q20939.2

Gene LinkOut

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