Gene description

fumarate hydratase

Locus Tag

Mb1128c

Gene type

protein coding

RefSeq status

PROVISIONAL

Organism

Mycobacterium bovis AF2122/97

Lineage

Bacteria; Actinobacteria; Actinobacteridae; Actinomycetales; Corynebacterineae; Mycobacteriaceae; Mycobacterium; Mycobacterium tuberculosis complex

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Names

fumarate hydratase

NP_854784.1

EC 4.2.1.2

class II family (does not require metal); tetrameric enzyme; fumarase C; reversibly converts (S)-malate to fumarate and water; functions in the TCA cycle

Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

This section includes genomic Reference Sequences (RefSeqs) from all assemblies on which this gene is annotated, such as RefSeqs for chromosomes and scaffolds (contigs) from both reference and alternate assemblies. Model RNAs and proteins are also reported here.

mRNA and Protein(s)

1. NP_854784.1 fumarate hydratase [Mycobacterium bovis AF2122/97]

   UniProtKB/Swiss-Prot

   Q7U0N6

   Conserved Domains (2) summary

   cd01362
   Location:11 – 463
   Blast Score: 1640

   Fumarase_classII; Class II fumarases. This group contains proteins similar to Escherichia coli fumarase C and the human mitochondrial fumarase. These proteins are members of the Lyase class I family. Members of this family for the most part catalyze similar beta...

   PRK00485
   Location:7 – 465
   Blast Score: 1978

   fumC; fumarate hydratase; Reviewed