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CTSB cathepsin B [ Macaca fascicularis (crab-eating macaque) ]

Gene ID: 101865017, updated on 3-Apr-2024

Summary

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Gene symbol
CTSB
Gene description
cathepsin B
See related
Ensembl:ENSMFAG00000014829
Gene type
protein coding
RefSeq status
MODEL
Organism
Macaca fascicularis
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Cercopithecidae; Cercopithecinae; Macaca
Orthologs
human mouse all
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Genomic context

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Location:
chromosome: 8
Exon count:
13
Annotation release Status Assembly Chr Location
102 current MFA1912RKSv2 (GCF_012559485.2) 8 NC_052262.1 (7697052..7721035)
101 previous assembly Macaca_fascicularis_5.0 (GCF_000364345.1) 8 NC_022279.1 (8857024..8866111)

Chromosome 8 - NC_052262.1Genomic Context describing neighboring genes Neighboring gene defensin beta 135 Neighboring gene defensin beta 136 Neighboring gene farnesyl-diphosphate farnesyltransferase 1 Neighboring gene activated RNA polymerase II transcriptional coactivator p15-like

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Substitution rate and structural divergence of 5'UTR evolution: comparative analysis between human and cynomolgus monkey cDNAs. Osada N, et al. Mol Biol Evol, 2005 Oct. PMID 15944441
  2. Rate of evolution in brain-expressed genes in humans and other primates. Wang HY, et al. PLoS Biol, 2007 Feb. PMID 17194215, Free PMC Article
  3. Genome sequencing and comparison of two nonhuman primate animal models, the cynomolgus and Chinese rhesus macaques. Yan G, et al. Nat Biotechnol, 2011 Oct 16. PMID 22002653

GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables cysteine-type endopeptidase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in proteolysis involved in protein catabolic process IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in regulation of catalytic activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in extracellular space IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in lysosome IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
cathepsin B
XP_045253772.1
XP_045253773.1
XP_045253774.1
XP_045253775.1
XP_045253776.1
XP_045253777.1
XP_045253778.1
XP_045253779.1
XP_045253780.1

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Macaca fascicularis Annotation Release 102 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference MFA1912RKSv2 Primary Assembly

Genomic

  1. NC_052262.1 Reference MFA1912RKSv2 Primary Assembly

    Range
    7697052..7721035
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_045397842.1 → XP_045253777.1  cathepsin B isoform X1

    UniProtKB/Swiss-Prot
    Q4R5M2
    UniProtKB/TrEMBL
    G7PCE3
    Conserved Domains (2) summary
    cd02620
    Location:81 → 328
    Peptidase_C1A_CathepsinB; Cathepsin B group; composed of cathepsin B and similar proteins, including tubulointerstitial nephritis antigen (TIN-Ag). Cathepsin B is a lysosomal papain-like cysteine peptidase which is expressed in all tissues and functions primarily as an ...
    pfam08127
    Location:26 → 65
    Propeptide_C1; Peptidase family C1 propeptide

  2. XM_045397841.1 → XP_045253776.1  cathepsin B isoform X1

    UniProtKB/Swiss-Prot
    Q4R5M2
    UniProtKB/TrEMBL
    G7PCE3
    Conserved Domains (2) summary
    cd02620
    Location:81 → 328
    Peptidase_C1A_CathepsinB; Cathepsin B group; composed of cathepsin B and similar proteins, including tubulointerstitial nephritis antigen (TIN-Ag). Cathepsin B is a lysosomal papain-like cysteine peptidase which is expressed in all tissues and functions primarily as an ...
    pfam08127
    Location:26 → 65
    Propeptide_C1; Peptidase family C1 propeptide

  3. XM_045397840.1 → XP_045253775.1  cathepsin B isoform X1

    UniProtKB/Swiss-Prot
    Q4R5M2
    UniProtKB/TrEMBL
    G7PCE3
    Conserved Domains (2) summary
    cd02620
    Location:81 → 328
    Peptidase_C1A_CathepsinB; Cathepsin B group; composed of cathepsin B and similar proteins, including tubulointerstitial nephritis antigen (TIN-Ag). Cathepsin B is a lysosomal papain-like cysteine peptidase which is expressed in all tissues and functions primarily as an ...
    pfam08127
    Location:26 → 65
    Propeptide_C1; Peptidase family C1 propeptide

  4. XM_045397839.1 → XP_045253774.1  cathepsin B isoform X1

    UniProtKB/Swiss-Prot
    Q4R5M2
    UniProtKB/TrEMBL
    G7PCE3
    Conserved Domains (2) summary
    cd02620
    Location:81 → 328
    Peptidase_C1A_CathepsinB; Cathepsin B group; composed of cathepsin B and similar proteins, including tubulointerstitial nephritis antigen (TIN-Ag). Cathepsin B is a lysosomal papain-like cysteine peptidase which is expressed in all tissues and functions primarily as an ...
    pfam08127
    Location:26 → 65
    Propeptide_C1; Peptidase family C1 propeptide

  5. XM_045397838.1 → XP_045253773.1  cathepsin B isoform X1

    UniProtKB/Swiss-Prot
    Q4R5M2
    UniProtKB/TrEMBL
    G7PCE3
    Conserved Domains (2) summary
    cd02620
    Location:81 → 328
    Peptidase_C1A_CathepsinB; Cathepsin B group; composed of cathepsin B and similar proteins, including tubulointerstitial nephritis antigen (TIN-Ag). Cathepsin B is a lysosomal papain-like cysteine peptidase which is expressed in all tissues and functions primarily as an ...
    pfam08127
    Location:26 → 65
    Propeptide_C1; Peptidase family C1 propeptide

  6. XM_045397844.1 → XP_045253779.1  cathepsin B isoform X1

    UniProtKB/Swiss-Prot
    Q4R5M2
    UniProtKB/TrEMBL
    G7PCE3
    Conserved Domains (2) summary
    cd02620
    Location:81 → 328
    Peptidase_C1A_CathepsinB; Cathepsin B group; composed of cathepsin B and similar proteins, including tubulointerstitial nephritis antigen (TIN-Ag). Cathepsin B is a lysosomal papain-like cysteine peptidase which is expressed in all tissues and functions primarily as an ...
    pfam08127
    Location:26 → 65
    Propeptide_C1; Peptidase family C1 propeptide

  7. XM_045397843.1 → XP_045253778.1  cathepsin B isoform X1

    UniProtKB/Swiss-Prot
    Q4R5M2
    UniProtKB/TrEMBL
    G7PCE3
    Conserved Domains (2) summary
    cd02620
    Location:81 → 328
    Peptidase_C1A_CathepsinB; Cathepsin B group; composed of cathepsin B and similar proteins, including tubulointerstitial nephritis antigen (TIN-Ag). Cathepsin B is a lysosomal papain-like cysteine peptidase which is expressed in all tissues and functions primarily as an ...
    pfam08127
    Location:26 → 65
    Propeptide_C1; Peptidase family C1 propeptide

  8. XM_045397837.1 → XP_045253772.1  cathepsin B isoform X1

    UniProtKB/Swiss-Prot
    Q4R5M2
    UniProtKB/TrEMBL
    G7PCE3
    Conserved Domains (2) summary
    cd02620
    Location:81 → 328
    Peptidase_C1A_CathepsinB; Cathepsin B group; composed of cathepsin B and similar proteins, including tubulointerstitial nephritis antigen (TIN-Ag). Cathepsin B is a lysosomal papain-like cysteine peptidase which is expressed in all tissues and functions primarily as an ...
    pfam08127
    Location:26 → 65
    Propeptide_C1; Peptidase family C1 propeptide

  9. XM_045397845.1 → XP_045253780.1  cathepsin B isoform X2

    Conserved Domains (1) summary
    cd02620
    Location:25 → 204
    Peptidase_C1A_CathepsinB; Cathepsin B group; composed of cathepsin B and similar proteins, including tubulointerstitial nephritis antigen (TIN-Ag). Cathepsin B is a lysosomal papain-like cysteine peptidase which is expressed in all tissues and functions primarily as an ...

Suppressed Reference Sequence(s)

The following Reference Sequences have been suppressed. Explain

  1. NM_001283485.1: Suppressed sequence

    Description
    NM_001283485.1: This RefSeq record was removed as a result of standard genome annotation processing. Contact info@ncbi.nlm.nih.gov for further information.
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q4R5M2.1 GenPept UniProtKB/Swiss-Prot:Q4R5M2

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