FOXL2 forkhead box L2 [Canis lupus familiaris (dog)] - Gene

Summary

Gene symbol: FOXL2
Gene description: forkhead box L2
See related: Ensembl:ENSCAFG00845026802
Gene type: protein coding
RefSeq status: MODEL
Organism: Canis lupus familiaris (sub-species: familiaris)
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Carnivora; Caniformia; Canidae; Canis
Orthologs: human mouse all
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Genomic context

Location:: chromosome: 23

Exon count:: 2

Annotation release	Status	Assembly	Chr	Location
106	current	ROS_Cfam_1.0 (GCF_014441545.1)	23	NC_051827.1 (35688052..35689311, complement)
106	current	Dog10K_Boxer_Tasha (GCF_000002285.5)	23	NC_006605.4 (35138304..35139560, complement)
106	current	UU_Cfam_GSD_1.0 (GCF_011100685.1)	23	NC_049244.1 (35684283..35685539, complement)
106	current	UMICH_Zoey_3.1 (GCF_005444595.1)	23	NC_049283.1 (35368849..35370105, complement)
106	current	UNSW_CanFamBas_1.0 (GCF_013276365.1)	23	NC_049764.1 (35433498..35434751, complement)

Chromosome 23 - NC_051827.1 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

It was concluded that the conducted research did not prove an association between these polymorphisms and canine testicular or ovotesticular XX DSD.
Title: Polymorphism of the CTNNB1 and FOXL2 Genes is not Associated with Canine XX Testicular/Ovotesticular Disorder of Sex Development.

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General gene information

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Markers

Foxl2 (e-PCR), detects polymorphism
- UniSTS:463206

Homology

NCBI Orthologs

Orthologs from OrthoDB

Gene Ontology Provided by RefSeq

Function	Evidence Code	Pubs
enables DNA-binding transcription factor activity, RNA polymerase II-specific	IEA Inferred from Electronic Annotation more info	PubMed
enables RNA polymerase II cis-regulatory region sequence-specific DNA binding	IEA Inferred from Electronic Annotation more info	PubMed

Process	Evidence Code	Pubs
involved_in anatomical structure morphogenesis	IEA Inferred from Electronic Annotation more info	PubMed
involved_in cell differentiation	IEA Inferred from Electronic Annotation more info	PubMed
involved_in regulation of transcription by RNA polymerase II	IEA Inferred from Electronic Annotation more info	PubMed

General protein information

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Preferred Names: LOW QUALITY PROTEIN: forkhead box protein L2; forkhead box protein L2

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Canis lupus familiaris Annotation Release 106 details...

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference ROS_Cfam_1.0

Genomic

NC_051827.1 Reference ROS_Cfam_1.0

Range

35688052..35689311 complement

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GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

XM_038431632.1 → XP_038287560.1 forkhead box protein L2 isoform X2

Related

ENSCAFT00845047274.1

Conserved Domains (1) summary

cd20028
Location:56 → 144

FH_FOXL2; Forkhead (FH) domain found in Forkhead box protein L2 (FOXL2) and similar proteins
XM_038431631.1 → XP_038287559.1 forkhead box protein L2 isoform X1

Conserved Domains (1) summary

cd20028
Location:74 → 162

FH_FOXL2; Forkhead (FH) domain found in Forkhead box protein L2 (FOXL2) and similar proteins

Alternate UMICH_Zoey_3.1

Genomic

NC_049283.1 Alternate UMICH_Zoey_3.1

Range

35368849..35370105 complement

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GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

XM_038508121.1 → XP_038364049.1 forkhead box protein L2 isoform X2

Conserved Domains (1) summary

cd20028
Location:56 → 144

FH_FOXL2; Forkhead (FH) domain found in Forkhead box protein L2 (FOXL2) and similar proteins
XM_038508120.1 → XP_038364048.1 forkhead box protein L2 isoform X1

Conserved Domains (1) summary

cd20028
Location:73 → 161

FH_FOXL2; Forkhead (FH) domain found in Forkhead box protein L2 (FOXL2) and similar proteins

Alternate UNSW_CanFamBas_1.0

Genomic

NC_049764.1 Alternate UNSW_CanFamBas_1.0

Range

35433498..35434751 complement

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GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

XM_038634378.1 → XP_038490306.1 LOW QUALITY PROTEIN: forkhead box protein L2 isoform X2

Alternate UU_Cfam_GSD_1.0

Genomic

NC_049244.1 Alternate UU_Cfam_GSD_1.0

Range

35684283..35685539 complement

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GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

XM_038570188.1 → XP_038426116.1 forkhead box protein L2 isoform X2

Conserved Domains (1) summary

cd20028
Location:56 → 144

FH_FOXL2; Forkhead (FH) domain found in Forkhead box protein L2 (FOXL2) and similar proteins
XM_038570187.1 → XP_038426115.1 forkhead box protein L2 isoform X1

Conserved Domains (1) summary

cd20028
Location:73 → 161

FH_FOXL2; Forkhead (FH) domain found in Forkhead box protein L2 (FOXL2) and similar proteins

Alternate Dog10K_Boxer_Tasha Primary Assembly

Genomic

NC_006605.4 Alternate Dog10K_Boxer_Tasha Primary Assembly

Range

35138304..35139560 complement

Download

GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

XM_038457467.1 → XP_038313395.1 forkhead box protein L2 isoform X2

Conserved Domains (1) summary

cd20028
Location:56 → 144

FH_FOXL2; Forkhead (FH) domain found in Forkhead box protein L2 (FOXL2) and similar proteins
XM_014106522.3 → XP_013961997.2 forkhead box protein L2 isoform X1

Conserved Domains (1) summary

cd20028
Location:73 → 161

FH_FOXL2; Forkhead (FH) domain found in Forkhead box protein L2 (FOXL2) and similar proteins